Transcription could be the key to the selection advantage of mitochondrial deletion mutants in aging

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 8, 2014, Pages 2972-2977

  Kowald, Axel ^a   Kirkwood, Thomas B L ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Mathematical model; Mitochondrial mutations

Indexed keywords

DNA POLYMERASE; MESSENGER RNA; MITOCHONDRIAL DNA;

ANIMAL CELL; ARTICLE; BIOINFORMATICS; DNA DEGRADATION; DNA REPLICATION; DNA SEQUENCE; DNA SYNTHESIS; DNA TRANSCRIPTION; HUMAN; HUMAN TISSUE; LIFE EXPECTANCY; MITOCHONDRIAL DELETION; MITOCHONDRIAL DYNAMICS; NONHUMAN; PRIORITY JOURNAL;

MATHEMATICAL MODEL; MITOCHONDRIAL MUTATIONS;

AGING; COMPUTER SIMULATION; DNA REPLICATION; DNA, MITOCHONDRIAL; MITOCHONDRIA; MODELS, BIOLOGICAL; SEQUENCE DELETION; TRANSCRIPTION, GENETIC;

EID: 84896810730     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1314970111     Document Type: Article

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