Impaired mitochondrial biogenesis precedes heart failure in right ventricular hypertrophy in congenital heart disease

Circulation: Heart Failure

Volumn 4, Issue 6, 2011, Pages 707-713

  Karamanlidis, Georgios ^a   Bautista Hernandez, Victor ^b   Fynn Thompson, Francis ^b   Del Nido, Pedro ^b   Tian, Rong ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Congenital heart disease; Mitochondrial biogenesis; MtDNA; PGC 1; RV failure

Indexed keywords

CITRATE SYNTHASE; MESSENGER RNA; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; PROTEIN; SUCCINATE DEHYDROGENASE; TFB1M PROTEIN; TFB2M PROTEIN; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR NRF2A; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ADOLESCENT; ADULT; ARTICLE; CELL ULTRASTRUCTURE; CHILD; CONGENITAL HEART DISEASE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HEART RIGHT VENTRICLE FAILURE; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE PRESSURE; HUMAN; HUMAN TISSUE; MALE; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL DNA REPLICATION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD; CASE CONTROL STUDY; DISEASE COURSE; DNA REPLICATION; ENZYMOLOGY; GENETICS; HEART DISEASE; HEART FAILURE; HEART MITOCHONDRION; INFANT; METABOLISM; PATHOLOGY; PROGNOSIS; ULTRASTRUCTURE;

ADOLESCENT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CITRATE (SI)-SYNTHASE; DISEASE PROGRESSION; DNA REPLICATION; DNA, MITOCHONDRIAL; FEMALE; HEART DISEASES; HEART FAILURE; HUMANS; HYPERTROPHY, RIGHT VENTRICULAR; INFANT; MALE; MITOCHONDRIA, HEART; PROGNOSIS; SUCCINATE DEHYDROGENASE; YOUNG ADULT;

EID: 84855598935     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.111.961474     Document Type: Article

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