Conformational equilibria of light-activated rhodopsin in nanodiscs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 16, 2017, Pages E3268-E3275

  Van Eps, Ned ^a,b,c   Caro, Lydia N ^c,f   Morizumi, Takefumi ^c   Kusnetzow, Ana Karin ^a,b,g   Szczepek, Michal ^d   Hofmann, Klaus Peter ^d   Bayburt, Timothy H ^e   Sligar, Stephen G ^e   Ernst, Oliver P ^c   Hubbell, Wayne L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JULES STEIN EYE INSTITUTE   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^f UNIVERSITÉ DE STRASBOURG   (France)

^g Crinetics Pharmaceuticals   (United States)

Author keywords

Conformational heterogeneity; Double electron electron resonance; GPCR; Nanodiscs; Rhodopsin

Indexed keywords

DODECYL MALTOSIDE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; LIPID; MALTOSE; NANODISC; PHOSPHOLIPID; PROTON; RECEPTOR; RHODOPSIN; TRANSDUCIN; UNCLASSIFIED DRUG; NANOMATERIAL; SPIN LABEL;

ARTICLE; CELL SURFACE; CONTROLLED STUDY; CYTOPLASM; ELECTRON RESONANCE SPECTROSCOPY; ELECTRON SPIN RESONANCE; EQUILIBRIUM CONSTANT; LIGHT; MEMBRANE; MICELLE; MOLECULAR RECOGNITION; NONHUMAN; PH; PHOTOACTIVATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS; SPECTRUM; SPIN LABELING; ANIMAL; BOVINE; CHEMISTRY; METABOLISM; PROTEIN SECONDARY STRUCTURE; RADIATION RESPONSE;

ANIMALS; CATTLE; LIGHT; NANOSTRUCTURES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RHODOPSIN; SPIN LABELS; TRANSDUCIN;

EID: 85017577400     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1620405114     Document Type: Article

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