Lipid Nanoparticle Systems for Enabling Gene Therapies

Molecular Therapy

Volumn 25, Issue 7, 2017, Pages 1467-1475

  Cullis, Pieter R ^a   Hope, Michael J ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Acuitas Therapeutics   (Canada)

Author keywords

gene editing; gene therapy; genetic drugs; lipid nanoparticles; mRNA; siRNA

Indexed keywords

LIPID NANOPARTICLE; MESSENGER RNA; NANOCARRIER; PLASMID DNA; PREALBUMIN; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VACCINE; ANTINEOPLASTIC AGENT; LIPID; NANOPARTICLE;

AMYLOIDOSIS; CLINICAL RESEARCH; DRUG APPROVAL; FOOD AND DRUG ADMINISTRATION; GENE EDITING; GENE SILENCING; GENE THERAPY; HUMAN; LIVER CELL; NANOTECHNOLOGY; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; REVIEW; ADMINISTRATION AND DOSAGE; ANIMAL; ATHEROSCLEROSIS; CHEMISTRY; CLINICAL TRIAL (TOPIC); DRUG DELIVERY SYSTEM; DRUG EFFECTS; FAMILIAL AMYLOID POLYNEUROPATHY; GENETICS; HEPATITIS B; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PATHOLOGY; PLASMID; PROCEDURES;

AMYLOID NEUROPATHIES, FAMILIAL; ANIMALS; ANTINEOPLASTIC AGENTS; ATHEROSCLEROSIS; CARCINOMA, HEPATOCELLULAR; CLINICAL TRIALS AS TOPIC; DRUG DELIVERY SYSTEMS; GENETIC THERAPY; HEPATITIS B; HEPATOCYTES; HUMANS; LIPIDS; LIVER NEOPLASMS; NANOPARTICLES; PLASMIDS; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 85017559707     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1016/j.ymthe.2017.03.013     Document Type: Review

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