Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 13, Issue 4, 2017, Pages 1377-1387

  Kulkarni, Jayesh A ^a   Myhre, Johnathan Layne ^a   Chen, Sam ^a   Tam, Yuen Yi C ^a   Danescu, Adrian ^a   Richman, Joy M ^a   Cullis, Pieter R ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Gene delivery; Gene expression; Lipid nanoparticles; Nanomedicine; Plasmid

Indexed keywords

BIOMOLECULES; CELL CULTURE; DNA; GENE TRANSFER; GENES; LIPIDS; LIPOSOMES; MAMMALS; MEDICAL NANOTECHNOLOGY; MOLECULAR BIOLOGY; NANOPARTICLES;

GENE DELIVERY; IONIZABLE AMINO LIPIDS; LIPID NANOPARTICLES; PLASMID; PRIMARY CELL CULTURES; REPORTER-GENE EXPRESSION; TRANSFECTION EFFICIENCY; TRANSFECTION REAGENTS;

GENE EXPRESSION;

1,3 DIOXOLANE; ENHANCED GREEN FLUORESCENT PROTEIN; LIPID; LIPID NANOPARTICLE; LIPOFECTAMINE; NANOPARTICLE; PLASMID DNA; UNCLASSIFIED DRUG; DNA;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENE SILENCING; HELA CELL LINE; IN VITRO GENE TRANSFER; IN VIVO GENE TRANSFER; LIMB BUD; LIPID COMPOSITION; MAMMAL CELL; MEMBRANE FUSION; MICROINJECTION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIMARY CELL; PRIMARY CELL CULTURE; REPORTER GENE; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CHEMISTRY; CHICK EMBRYO; DRUG DELIVERY SYSTEM; GENETIC TRANSFECTION; HUMAN; MOUSE; PLASMID; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CHICK EMBRYO; DNA; DRUG DELIVERY SYSTEMS; HELA CELLS; HUMANS; LIPIDS; MICE; NANOPARTICLES; PLASMIDS; TRANSFECTION;

EID: 85017117510     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2016.12.014     Document Type: Article

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