Phenotype and tissue residency of lymphocytes in the murine oral mucosa

Frontiers in Immunology

Volumn 8, Issue MAR, 2017, Pages

  Park, Joo Young ^a   Chung, Hyunsoo ^a   Choi, Youngnim ^b   Park, Jung Hyun ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Seoul National University   (South Korea)

Author keywords

Cell isolation; Cellular immunity; Collagenases; Flow cytometry; Maxillofacial; Monocytes

Indexed keywords

CD103 ANTIGEN; CD11B ANTIGEN; CD69 ANTIGEN; FINGOLIMOD; LIBERASE; THERMOLYSIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BONE MARROW CELL; CD8+ T LYMPHOCYTE; CELL COMPOSITION; CELL ISOLATION; CELLULAR DISTRIBUTION; CLINICAL PROTOCOL; FEMALE; FLOW CYTOMETRY; IMMUNOSURVEILLANCE; LEUKOCYTE; LYMPHOCYTE; LYMPHOCYTE SUBPOPULATION; MALE; MOUSE; NONHUMAN; PHENOTYPE; T LYMPHOCYTE; TISSUE DISTRIBUTION;

EID: 85017256443     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2017.00250     Document Type: Article

References (46)

1. Takahashi N. Oral microbiome metabolism: from "who are they?" to "what are they doing?". J Dent Res (2015) 94(12):1628-37. doi:10.1177/0022034515606045
2. Paster BJ, Boches SK, Galvin JL, Ericson RE, Lau CN, Levanos VA, et al. Bacterial diversity in human subgingival plaque. J Bacteriol (2001) 183(12):3770-83. doi:10.1128/JB.183.12.3770-3783.2001
3. Kistler JO, Booth V, Bradshaw DJ, Wade WG. Bacterial community development in experimental gingivitis. PLoS One (2013) 8(8):e71227. doi:10.1371/journal.pone.0071227
4. Novak N, Haberstok J, Bieber T, Allam JP. The immune privilege of the oral mucosa. Trends Mol Med (2008) 14(5):191-8. doi:10.1016/j.molmed.2008.03.001
5. Corthesy B, Spertini F. Secretory immunoglobulin A: from mucosal protection to vaccine development. Biol Chem (1999) 380(11):1251-62. doi:10.1515/BC.1999.160
6. Fabian TK, Hermann P, Beck A, Fejerdy P, Fabian G. Salivary defense proteins: their network and role in innate and acquired oral immunity. Int J Mol Sci (2012) 13(4):4295-320. doi:10.3390/ijms13044295
7. Gorr SU. Antimicrobial peptides of the oral cavity. Periodontol 2000 (2009) 51:152-80. doi:10.1111/j.1600-0757.2009.00310.x
8. Diamond G, Beckloff N, Ryan LK. Host defense peptides in the oral cavity and the lung: similarities and differences. J Dent Res (2008) 87(10):915-27. doi:10.1177/154405910808701011
9. Hovav AH. Dendritic cells of the oral mucosa. Mucosal Immunol (2014) 7(1):27-37. doi:10.1038/mi.2013.42
10. Squier CA, Kremer MJ. Biology of oral mucosa and esophagus. J Natl Cancer Inst Monogr (2001) 29:7-15. doi:10.1093/oxfordjournals.jncimonographs.a003443
11. Dawson DV, Drake DR, Hill JR, Brogden KA, Fischer CL, Wertz PW. Organization, barrier function and antimicrobial lipids of the oral mucosa. Int J Cosmet Sci (2013) 35(3):220-3. doi:10.1111/ics.12038
12. Mascarell L, Lombardi V, Zimmer A, Louise A, Tourdot S, Van Overtvelt L, et al. Mapping of the lingual immune system reveals the presence of both regulatory and effector CD4+T cells. Clin Exp Allergy (2009) 39(12):1910-9. doi:10.1111/j.1365-2222.2009.03337.x
13. Heath WR, Carbone FR. The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells. Nat Immunol (2013) 14(10):978-85. doi:10.1038/ni.2680
14. Masopust D, Vezys V, Marzo AL, Lefrancois L. Preferential localization of effector memory cells in nonlymphoid tissue. Science (2001) 291(5512):2413-7. doi:10.1126/science.1058867
15. Gebhardt T, Wakim LM, Eidsmo L, Reading PC, Heath WR, Carbone FR. Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus. Nat Immunol (2009) 10(5):524-30. doi:10.1038/ni.1718
16. Masopust D, Choo D, Vezys V, Wherry EJ, Duraiswamy J, Akondy R, et al. Dynamic T cell migration program provides resident memory within intestinal epithelium. J Exp Med (2010) 207(3):553-64. doi:10.1084/jem.20090858
17. Edelson BT, Kc W, Juang R, Kohyama M, Benoit LA, Klekotka PA, et al. Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells. J Exp Med (2010) 207(4):823-36. doi:10.1084/jem.20091627
18. Allam JP, Duan Y, Heinemann F, Winter J, Gotz W, Deschner J, et al. IL-23-producing CD68(+) macrophage-like cells predominate within an IL-17-polarized infiltrate in chronic periodontitis lesions. J Clin Periodontol (2011) 38(10):879-86. doi:10.1111/j.1600-051X.2011.01752.x
19. Capucha T, Mizraji G, Segev H, Blecher-Gonen R, Winter D, Khalaileh A, et al. Distinct murine mucosal Langerhans cell subsets develop from pre-dendritic cells and monocytes. Immunity (2015) 43(2):369-81. doi:10.1016/j.immuni.2015.06.017
20. Mascarell L, Lombardi V, Louise A, Saint-Lu N, Chabre H, Moussu H, et al. Oral dendritic cells mediate antigen-specific tolerance by stimulating T(H)1 and regulatory CD(4+) T cells. J Allergy ClinImmunol (2008) 122(3):603-9. doi:10.1016/j.jaci.2008.06.034
21. Mascarell L, Saint-Lu N, Moussu H, Zimmer A, Louise A, Lone Y, et al. Oral macrophage-like cells play a key role in tolerance induction following sublingual immunotherapy of asthmatic mice. Mucosal Immunol (2011) 4(6):638-47. doi:10.1038/mi.2011.28
22. Song JH, Kim JI, Kwon HJ, Shim DH, Parajuli N, Cuburu N, et al. CCR7-CCL19/CCL21-regulated dendritic cells are responsible for effectiveness of sublingual vaccination. J Immunol (2009) 182(11):6851-60. doi:10.4049/jimmunol.0803568
23. Goodyear AW, Kumar A, Dow S, Ryan EP. Optimization of murine small intestine leukocyte isolation for global immune phenotype analysis. J Immunol Methods (2014) 405:97-108. doi:10.1016/j.jim.2014.01.014
24. Steinert EM, Schenkel JM, Fraser KA, Beura LK, Manlove LS, Igyarto BZ, et al. Quantifying memory CD8 T cells reveals regionalization of immunosurveillance. Cell (2015) 161(4):737-49. doi:10.1016/j.cell.2015.03.031
25. Pandiyan P, Bhaskaran N, Zhang Y, Weinberg A. Isolation of T cells from mouse oral tissues. Biol Proced Online (2014) 16(1):4. doi:10.1186/1480-9222-16-4
26. Chao CC, Jensen R, Dailey MO. Mechanisms of L-selectin regulation by activated T cells. J Immunol (1997) 159(4):1686-94.
27. Vareille M, Kieninger E, Edwards MR, Regamey N. The airway epithelium: soldier in the fight against respiratory viruses. Clin Microbiol Rev (2011) 24(1):210-29. doi:10.1128/CMR.00014-10
28. Lee YJ, Wang H, Starrett GJ, Phuong V, Jameson SC, Hogquist KA. Tissue-specific distribution of iNKT cells impacts their cytokine response. Immunity (2015) 43(3):566-78. doi:10.1016/j.immuni.2015.06.025
29. Lynch L, Nowak M, Varghese B, Clark J, Hogan AE, Toxavidis V, et al. Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production. Immunity (2012) 37(3):574-87. doi:10.1016/j.immuni.2012.06.016
30. Barrett AW, Cruchley AT, Williams DM. Oral mucosal Langerhans' cells. Crit Rev Oral Biol Med (1996) 7(1):36-58. doi:10.1177/10454411960070010301
31. Ginhoux F, Jung S. Monocytes and macrophages: developmental pathways and tissue homeostasis. Nat Rev Immunol (2014) 14(6):392-404. doi:10.1038/nri3671
32. Sunderkotter C, Nikolic T, Dillon MJ, Van Rooijen N, Stehling M, Drevets DA, et al. Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol (2004) 172(7):4410-7. doi:10.4049/jimmunol.172.7.4410
33. Chorro L, Geissmann F. Development and homeostasis of 'resident' myeloid cells: the case of the Langerhans cell. Trends Immunol (2010) 31(12):438-45. doi:10.1016/j.it.2010.09.003
34. Baaten BJ, Li CR, Deiro MF, Lin MM, Linton PJ, Bradley LM. CD44 regulates survival and memory development in Th1 cells. Immunity (2010) 32(1):104-15. doi:10.1016/j.immuni.2009.10.011
35. Agace WW, Higgins JM, Sadasivan B, Brenner MB, Parker CM. T-lymphocyte-epithelial-cell interactions: integrin alpha(E)(CD103)beta(7), LEEP-CAM and chemokines. Curr Opin Cell Biol (2000) 12(5):563-8. doi:10.1016/S0955-0674(00)00132-0
36. Park CO, Kupper TS. The emerging role of resident memory T cells in protective immunity and inflammatory disease. Nat Med (2015) 21(7):688-97. doi:10.1038/nm.3883
37. Schenkel JM, Fraser KA, Vezys V, Masopust D. Sensing and alarm function of resident memory CD8(+) T cells. Nat Immunol (2013) 14(5):509-13. doi:10.1038/ni.2568
38. Chiba K. FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors. Pharmacol Ther (2005) 108(3):308-19. doi:10.1016/j.pharmthera.2005.05.002
39. Bankovich AJ, Shiow LR, Cyster JG. CD69 suppresses sphingosine 1-phosophate receptor-1 (S1P1) function through interaction with membrane helix 4. J Biol Chem (2010) 285(29):22328-37. doi:10.1074/jbc.M110.123299
40. Cutler CW, Jotwani R. Dendritic cells at the oral mucosal interface. J Dent Res (2006) 85(8):678-89. doi:10.1177/154405910608500801
41. Tanaka Y, Nagashima H, Bando K, Lu L, Ozaki A, Morita Y, et al. Oral CD103-CD11b+ classical dendritic cells present sublingual antigen and induce Foxp3+ regulatory T cells in draining lymph nodes. Mucosal Immunol (2017) 10(1):79-90. doi:10.1038/mi.2016.46
42. Birkedal-Hansen H, Moore WG, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A, et al. Matrix metalloproteinases: a review. Crit Rev Oral Biol Med (1993) 4(2):197-250. doi:10.1177/10454411930040020401
43. Benya RV, Schmidt LN, Sahi J, Layden TJ, Rao MC. Isolation, characterization, and attachment of rabbit distal colon epithelial cells. Gastroenterology (1991) 101(3):692-702. doi:10.1016/0016-5085(91)90527-R
44. Schwab SR, Cyster JG. Finding a way out: lymphocyte egress from lymphoid organs. Nat Immunol (2007) 8(12):1295-301. doi:10.1038/ni1545
45. Shiow LR, Rosen DB, Brdickova N, Xu Y, An J, Lanier LL, et al. CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature (2006) 440(7083):540-4. doi:10.1038/nature04606
46. Takamura S, Yagi H, Hakata Y, Motozono C, McMaster SR, Masumoto T, et al. Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance. J Exp Med (2016) 213(13):3057-73. doi:10.1084/jem.20160938