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Volumn 1, Issue 1, 2014, Pages 375-398

Vaccine development as a means to control dengue virus pathogenesis: Do we know enough?

Author keywords

Antibody; Cellular immunity; Flavivirus; Humoral immunity; Neutralization; Pathogenesis

Indexed keywords

ANTIBODY; CHIMERIC YELLOW FEVER DENGUE TETRAVALENT DENGUE VACCINE; DENGUE VACCINE; DNA PLASMID VACCINE; DNA VACCINE; LIVE VACCINE; SUBUNIT VACCINE; UNCLASSIFIED DRUG;

EID: 85016959543     PISSN: 2327056X     EISSN: 23270578     Source Type: Journal    
DOI: 10.1146/annurev-virology-031413-085453     Document Type: Article
Times cited : (14)

References (154)
  • 1
    • 0002128020 scopus 로고
    • An account of the bilious remitting fever, as it appeared in Philadelphia, in the summer and autumn of the year 1780
    • Philadelphia: Prichard & Hall
    • Rush AB. 1789. An account of the bilious remitting fever, as it appeared in Philadelphia, in the summer and autumn of the year 1780. In Medical Inquiries and Observations, pp. 104-17. Philadelphia: Prichard & Hall
    • (1789) Medical Inquiries and Observations , pp. 104-117
    • Rush, A.B.1
  • 2
    • 34548733678 scopus 로고    scopus 로고
    • Research on dengue and dengue-like illness in East Asia and theWestern Pacific during the first half of the 20th century
    • Kuno G. 2007. Research on dengue and dengue-like illness in East Asia and theWestern Pacific during the first half of the 20th century. Rev. Med. Virol. 17:327-41
    • (2007) Rev. Med. Virol. , vol.17 , pp. 327-341
    • Kuno, G.1
  • 3
    • 10944252079 scopus 로고    scopus 로고
    • Emerging flaviviruses: The spread and resurgence of Japanese encephalitis,West Nile and dengue viruses
    • Mackenzie JS, Gubler DJ, Petersen LR. 2004. Emerging flaviviruses: the spread and resurgence of Japanese encephalitis,West Nile and dengue viruses. Nat. Med. 10:S98-109
    • (2004) Nat. Med. , vol.10 , pp. S98-109
    • Mackenzie, J.S.1    Gubler, D.J.2    Petersen, L.R.3
  • 6
    • 0024446830 scopus 로고
    • Dengue haemorrhagic fever/dengue shock syndrome: Lessons from the Cuban epidemic, 1981
    • Kouri GP, Guzman MG, Bravo JR, Triana C. 1989. Dengue haemorrhagic fever/dengue shock syndrome: lessons from the Cuban epidemic, 1981. Bull. World Health Organ. 67:375-80
    • (1989) Bull. World Health Organ. , vol.67 , pp. 375-380
    • Kouri, G.P.1    Guzman, M.G.2    Bravo, J.R.3    Triana, C.4
  • 8
    • 78449257072 scopus 로고    scopus 로고
    • Dengue virus ensures its fusion in late endosomes using compartment-specific lipids
    • Zaitseva E, Yang ST, Melikov K, Pourmal S, Chernomordik LV. 2010. Dengue virus ensures its fusion in late endosomes using compartment-specific lipids. PLoS Pathog. 6:e1001131
    • (2010) PLoS Pathog. , vol.6 , pp. e1001131
    • Zaitseva, E.1    Yang, S.T.2    Melikov, K.3    Pourmal, S.4    Chernomordik, L.V.5
  • 10
    • 0037236396 scopus 로고    scopus 로고
    • Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus
    • Elshuber S, Allison SL, Heinz FX,Mandl CW. 2003. Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus. J. Gen. Virol. 84:183-91
    • (2003) J. Gen. Virol. , vol.84 , pp. 183-191
    • Elshuber, S.1    Allison, S.L.2    Heinz, F.X.3    Mandl, C.W.4
  • 11
    • 0030764780 scopus 로고    scopus 로고
    • Proteolytic activation of tick-borne encephalitis virus by furin
    • Stadler K, Allison SL, Schalich J, Heinz FX. 1997. Proteolytic activation of tick-borne encephalitis virus by furin. J. Virol. 71:8475-81
    • (1997) J. Virol. , vol.71 , pp. 8475-8481
    • Stadler, K.1    Allison, S.L.2    Schalich, J.3    Heinz, F.X.4
  • 12
    • 78650608263 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the early steps of flavivirus cell entry
    • Kaufmann B, Rossmann MG. 2011. Molecular mechanisms involved in the early steps of flavivirus cell entry. Microbes Infect. 13:1-9
    • (2011) Microbes Infect. , vol.13 , pp. 1-9
    • Kaufmann, B.1    Rossmann, M.G.2
  • 13
    • 44449143037 scopus 로고    scopus 로고
    • Maturation of West Nile virus modulates sensitivity to antibody-mediated neutralization
    • Nelson S, Jost CA, Xu Q, Ess J, Martin JE, et al. 2008. Maturation of West Nile virus modulates sensitivity to antibody-mediated neutralization. PLoS Pathog. 4:e1000060
    • (2008) PLoS Pathog. , vol.4 , pp. e1000060
    • Nelson, S.1    Jost, C.A.2    Xu, Q.3    Ess, J.4    Martin, J.E.5
  • 14
    • 41349112506 scopus 로고    scopus 로고
    • The flavivirus precursor membrane-envelope protein complex: Structure and maturation
    • Li L, Lok SM, Yu IM, Zhang Y, Kuhn RJ, et al. 2008. The flavivirus precursor membrane-envelope protein complex: structure and maturation. Science 319:1830-34
    • (2008) Science , vol.319 , pp. 1830-1834
    • Li, L.1    Lok, S.M.2    Yu, I.M.3    Zhang, Y.4    Kuhn, R.J.5
  • 15
    • 18344387519 scopus 로고    scopus 로고
    • Structure of dengue virus: Implications for flavivirus organization, maturation, and fusion
    • Kuhn RJ, Zhang W, Rossmann MG, Pletnev SV, Corver J, et al. 2002. Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell 108:717-25
    • (2002) Cell , vol.108 , pp. 717-725
    • Kuhn, R.J.1    Zhang, W.2    Rossmann, M.G.3    Pletnev, S.V.4    Corver, J.5
  • 16
    • 26944454471 scopus 로고    scopus 로고
    • Structural basis for neutralization of a therapeutic antibody against West Nile virus
    • Nybakken G, Oliphant T, Johnson S, Burke S, Diamond MS, Fremont DH. 2005. Structural basis for neutralization of a therapeutic antibody against West Nile virus. Nature 437:764-69
    • (2005) Nature , vol.437 , pp. 764-769
    • Nybakken, G.1    Oliphant, T.2    Johnson, S.3    Burke, S.4    Diamond, M.S.5    Fremont, D.H.6
  • 18
    • 78650495030 scopus 로고    scopus 로고
    • Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354
    • Kaufmann B, Vogt MR, Goudsmit J, Holdaway HA, Aksyuk AA, et al. 2010. Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proc. Natl. Acad. Sci. USA 107:18950-55
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 18950-18955
    • Kaufmann, B.1    Vogt, M.R.2    Goudsmit, J.3    Holdaway, H.A.4    Aksyuk, A.A.5
  • 19
    • 84860826712 scopus 로고    scopus 로고
    • Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions
    • de Alwis R, Smith SA,Olivarez NP,Messer WB, Huynh JP, et al. 2012. Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. Proc. Natl. Acad. Sci. USA 109:7439-44
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 7439-7444
    • De Alwis, R.1    Smith, S.A.2    Olivarez, N.P.3    Messer, W.B.4    Huynh, J.P.5
  • 20
    • 84862850400 scopus 로고    scopus 로고
    • The structural basis for serotype-specific neutralization of dengue virus by a human antibody
    • Teoh EP, Kukkaro P, Teo EW, Lim AP, Tan TT, et al. 2012. The structural basis for serotype-specific neutralization of dengue virus by a human antibody. Sci. Transl. Med. 4:139ra183
    • (2012) Sci. Transl. Med. , vol.4 , pp. 139ra183
    • Teoh, E.P.1    Kukkaro, P.2    Teo, E.W.3    Lim, A.P.4    Tan, T.T.5
  • 21
    • 33744919581 scopus 로고    scopus 로고
    • High seroprevalence of antibodies against dengue virus in a prospective study of schoolchildren in Managua, Nicaragua
    • Balmaseda A, Hammond SN, Tellez Y, Imhoff L, Rodriguez Y, et al. 2006. High seroprevalence of antibodies against dengue virus in a prospective study of schoolchildren in Managua, Nicaragua. Trop. Med. Int. Health 11:935-42
    • (2006) Trop. Med. Int. Health , vol.11 , pp. 935-942
    • Balmaseda, A.1    Hammond, S.N.2    Tellez, Y.3    Imhoff, L.4    Rodriguez, Y.5
  • 23
    • 0036642434 scopus 로고    scopus 로고
    • Epidemiology of inapparent and symptomatic acute dengue virus infection: A prospective study of primary school children in Kamphaeng Phet, Thailand
    • Endy TP, Chunsuttiwat S,Nisalak A, LibratyDH, Green S, et al. 2002. Epidemiology of inapparent and symptomatic acute dengue virus infection: a prospective study of primary school children in Kamphaeng Phet, Thailand. Am. J. Epidemiol. 156:40-51
    • (2002) Am. J. Epidemiol. , vol.156 , pp. 40-51
    • Endy, T.P.1    Chunsuttiwat, S.2    Nisalak, A.3    Libraty, D.H.4    Green, S.5
  • 24
    • 76949113583 scopus 로고
    • Research on dengue duringWorld War II
    • Sabin AB. 1952. Research on dengue duringWorld War II. Am. J. Trop. Med. Hyg. 1:30-50
    • (1952) Am. J. Trop. Med. Hyg. , vol.1 , pp. 30-50
    • Sabin, A.B.1
  • 25
    • 33845323694 scopus 로고    scopus 로고
    • Post-infectious fatigue syndrome in dengue infection
    • Seet RC, Quek AM, Lim EC. 2007. Post-infectious fatigue syndrome in dengue infection. J. Clin. Virol. 38:1-6
    • (2007) J. Clin. Virol. , vol.38 , pp. 1-6
    • Seet, R.C.1    Quek, A.M.2    Lim, E.C.3
  • 26
    • 35748929379 scopus 로고    scopus 로고
    • Dengue
    • Halstead SB. 2007. Dengue. Lancet 370:1644-52
    • (2007) Lancet , vol.370 , pp. 1644-1652
    • Halstead, S.B.1
  • 28
    • 0033970916 scopus 로고    scopus 로고
    • Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity
    • Vaughn DW, Green S, Kalayanarooj S, Innis BL, Nimmannitya S, et al. 2000. Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. J. Infect. Dis. 181:2-9
    • (2000) J. Infect. Dis. , vol.181 , pp. 2-9
    • Vaughn, D.W.1    Green, S.2    Kalayanarooj, S.3    Innis, B.L.4    Nimmannitya, S.5
  • 29
    • 0034003808 scopus 로고    scopus 로고
    • Prospective study of the duration and magnitude of viraemia in children hospitalised during the 1996-1997 dengue-2 outbreak in French Polynesia
    • Murgue B, Roche C, Chungue E, Deparis X. 2000. Prospective study of the duration and magnitude of viraemia in children hospitalised during the 1996-1997 dengue-2 outbreak in French Polynesia. J. Med. Virol. 60:432-38
    • (2000) J. Med. Virol. , vol.60 , pp. 432-438
    • Murgue, B.1    Roche, C.2    Chungue, E.3    Deparis, X.4
  • 30
    • 0036569001 scopus 로고    scopus 로고
    • Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections
    • Libraty DH, Endy TP, Houng HS, Green S, Kalayanarooj S, et al. 2002. Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections. J. Infect. Dis. 185:1213-21
    • (2002) J. Infect. Dis. , vol.185 , pp. 1213-1221
    • Libraty, D.H.1    Endy, T.P.2    Houng, H.S.3    Green, S.4    Kalayanarooj, S.5
  • 31
    • 0035245276 scopus 로고    scopus 로고
    • Acute management of dengue shock syndrome: A randomized double-blind comparison of 4 intravenous fluid regimens in the first hour
    • Ngo NT, Cao XT, Kneen R, Wills B, Nguyen VM, et al. 2001. Acute management of dengue shock syndrome: a randomized double-blind comparison of 4 intravenous fluid regimens in the first hour. Clin. Infect. Dis. 32:204-13
    • (2001) Clin. Infect. Dis. , vol.32 , pp. 204-213
    • Ngo, N.T.1    Cao, X.T.2    Kneen, R.3    Wills, B.4    Nguyen, V.M.5
  • 34
    • 0032840738 scopus 로고    scopus 로고
    • A prospective seroepidemiologic study on dengue in children four to nine years of age in Yogyakarta, Indonesia. I. Studies in 1995-1996
    • Graham RR, JuffrieM, Tan R, Hayes CG, Laksono I, et al. 1999. A prospective seroepidemiologic study on dengue in children four to nine years of age in Yogyakarta, Indonesia. I. Studies in 1995-1996. Am. J. Trop. Med. Hyg. 61:412-19
    • (1999) Am. J. Trop. Med. Hyg. , vol.61 , pp. 412-419
    • Graham, R.R.1    Juffrie, M.2    Tan, R.3    Hayes, C.G.4    Laksono, I.5
  • 36
    • 34447641805 scopus 로고    scopus 로고
    • Maternal antibody and viral factors in the pathogenesis of dengue virus in infants
    • Simmons CP, Chau TN, Thuy TT, Tuan NM, Hoang DM, et al. 2007. Maternal antibody and viral factors in the pathogenesis of dengue virus in infants. J. Infect. Dis. 196:416-24
    • (2007) J. Infect. Dis. , vol.196 , pp. 416-424
    • Simmons, C.P.1    Chau, T.N.2    Thuy, T.T.3    Tuan, N.M.4    Hoang, D.M.5
  • 37
    • 0023864994 scopus 로고
    • Evidence that maternal dengue antibodies are important in the development of dengue hemorrhagic fever in infants
    • Kliks SC, Nimmanitya S, Nisalak A, Burke DS. 1988. Evidence that maternal dengue antibodies are important in the development of dengue hemorrhagic fever in infants. Am. J. Trop.Med. Hyg. 38:411-19
    • (1988) Am. J. Trop.Med. Hyg. , vol.38 , pp. 411-419
    • Kliks, S.C.1    Nimmanitya, S.2    Nisalak, A.3    Burke, D.S.4
  • 38
    • 70449122704 scopus 로고    scopus 로고
    • A prospective nested case-control study of dengue in infants: Rethinking and refining the antibody-dependent enhancement dengue hemorrhagic fever model
    • Libraty DH, Acosta LP, Tallo V, Segubre-Mercado E, Bautista A, et al. 2009. A prospective nested case-control study of dengue in infants: rethinking and refining the antibody-dependent enhancement dengue hemorrhagic fever model. PLoS Med. 6:e1000171
    • (2009) PLoS Med. , vol.6 , pp. e1000171
    • Libraty, D.H.1    Acosta, L.P.2    Tallo, V.3    Segubre-Mercado, E.4    Bautista, A.5
  • 39
    • 39749143370 scopus 로고    scopus 로고
    • Concurrent infections by all four dengue virus serotypes during an outbreak of dengue in 2006 in Delhi, India
    • Bharaj P, Chahar HS, Pandey A, Diddi K, Dar L, et al. 2008. Concurrent infections by all four dengue virus serotypes during an outbreak of dengue in 2006 in Delhi, India. Virol. J. 5:1
    • (2008) Virol. J. , vol.5 , pp. 1
    • Bharaj, P.1    Chahar, H.S.2    Pandey, A.3    Diddi, K.4    Dar, L.5
  • 40
    • 55049084757 scopus 로고    scopus 로고
    • Geographic expansion of dengue: The impact of international travel
    • Wilder-Smith A, Gubler DJ. 2008. Geographic expansion of dengue: the impact of international travel. Med. Clin. N. Am. 92:1377-90
    • (2008) Med. Clin. N. Am. , vol.92 , pp. 1377-1390
    • Wilder-Smith, A.1    Gubler, D.J.2
  • 41
    • 50849098592 scopus 로고    scopus 로고
    • Global spread and persistence of dengue
    • Kyle JL, Harris E. 2008. Global spread and persistence of dengue. Annu. Rev. Microbiol. 62:71-92
    • (2008) Annu. Rev. Microbiol. , vol.62 , pp. 71-92
    • Kyle, J.L.1    Harris, E.2
  • 42
    • 0000003107 scopus 로고
    • Production of immunity to dengue with virusmodified by propagation in mice
    • Sabin AB, Schlesinger RW. 1945. Production of immunity to dengue with virusmodified by propagation in mice. Science 101:640-42
    • (1945) Science , vol.101 , pp. 640-642
    • Sabin, A.B.1    Schlesinger, R.W.2
  • 43
    • 85025396219 scopus 로고
    • The use of yellow fever virus modified by in vitro cultivation for human immunization
    • Theiler M, Smith HH. 1937. The use of yellow fever virus modified by in vitro cultivation for human immunization. J. Exp. Med. 65:787-800
    • (1937) J. Exp. Med. , vol.65 , pp. 787-800
    • Theiler, M.1    Smith, H.H.2
  • 44
    • 84891086828 scopus 로고    scopus 로고
    • Dengue virus vaccine development
    • Yauch LE, Shresta S. 2014. Dengue virus vaccine development. Adv. Virus Res. 88:315-72
    • (2014) Adv. Virus Res. , vol.88 , pp. 315-372
    • Yauch, L.E.1    Shresta, S.2
  • 45
    • 67049086866 scopus 로고    scopus 로고
    • Yellow fever vaccine-how does it work and why do rare cases of serious adverse events take place?
    • Barrett AD, Teuwen DE. 2009. Yellow fever vaccine-how does it work and why do rare cases of serious adverse events take place? Curr. Opin. Immunol. 21:308-13
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 308-313
    • Barrett, A.D.1    Teuwen, D.E.2
  • 46
    • 80052406004 scopus 로고    scopus 로고
    • From research to phase III: Preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine
    • Guy B, Barrere B, Malinowski C, Saville M, Teyssou R, Lang J. 2011. From research to phase III: preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine. Vaccine 29:7229-41
    • (2011) Vaccine , vol.29 , pp. 7229-7241
    • Guy, B.1    Barrere, B.2    Malinowski, C.3    Saville, M.4    Teyssou, R.5    Lang, J.6
  • 47
  • 48
    • 84892649729 scopus 로고    scopus 로고
    • Comparison of the live attenuated yellow fever vaccine 17D-204 strain to its virulent parental strain Asibi by deep sequencing
    • Beck A, Tesh RB, Wood TG, Widen SG, Ryman KD, Barrett AD. 2013. Comparison of the live attenuated yellow fever vaccine 17D-204 strain to its virulent parental strain Asibi by deep sequencing. J. Infect. Dis. 209:334-44
    • (2013) J. Infect. Dis. , vol.209 , pp. 334-344
    • Beck, A.1    Tesh, R.B.2    Wood, T.G.3    Widen, S.G.4    Ryman, K.D.5    Barrett, A.D.6
  • 49
    • 0346817393 scopus 로고    scopus 로고
    • Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys
    • Whitehead SS, Hanley KA, Blaney JE Jr, Gilmore LE, Elkins WR, Murphy BR. 2003. Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys. Vaccine 21:4307-16
    • (2003) Vaccine , vol.21 , pp. 4307-4316
    • Whitehead, S.S.1    Hanley, K.A.2    Blaney, J.E.3    Gilmore, L.E.4    Elkins, W.R.5    Murphy, B.R.6
  • 50
    • 33745237160 scopus 로고    scopus 로고
    • Live attenuated chimeric yellow fever dengue type 2 (ChimeriVaxTM-DEN2) vaccine: Phase i clinical trial for safety and immunogenicity: Effect of yellow fever pre-immunity in induction of cross neutralizing antibody responses to all 4 dengue serotypes
    • Guirakhoo F, Kitchener S, Morrison D, Forrat R, McCarthy K, et al. 2006. Live attenuated chimeric yellow fever dengue type 2 (ChimeriVaxTM-DEN2) vaccine: phase I clinical trial for safety and immunogenicity: effect of yellow fever pre-immunity in induction of cross neutralizing antibody responses to all 4 dengue serotypes. Hum. Vaccines 2:60-67
    • (2006) Hum. Vaccines , vol.2 , pp. 60-67
    • Guirakhoo, F.1    Kitchener, S.2    Morrison, D.3    Forrat, R.4    McCarthy, K.5
  • 51
    • 75649131888 scopus 로고    scopus 로고
    • A novel tetravalent dengue vaccine is well tolerated and immunogenic against all 4 serotypes in flavivirus-naive adults
    • Morrison D, Legg TJ, Billings CW, Forrat R, Yoksan S, Lang J. 2010. A novel tetravalent dengue vaccine is well tolerated and immunogenic against all 4 serotypes in flavivirus-naive adults. J. Infect. Dis. 201:370-77
    • (2010) J. Infect. Dis. , vol.201 , pp. 370-377
    • Morrison, D.1    Legg, T.J.2    Billings, C.W.3    Forrat, R.4    Yoksan, S.5    Lang, J.6
  • 52
    • 84868211668 scopus 로고    scopus 로고
    • Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: A randomised, controlled phase 2b trial
    • Sabchareon A, Wallace D, Sirivichayakul C, Limkittikul K, Chanthavanich P, et al. 2012. Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial. Lancet 380:1559-67
    • (2012) Lancet , vol.380 , pp. 1559-1567
    • Sabchareon, A.1    Wallace, D.2    Sirivichayakul, C.3    Limkittikul, K.4    Chanthavanich, P.5
  • 53
    • 80052406524 scopus 로고    scopus 로고
    • Development and clinical evaluation of multiple investigational monovalent DENV vaccines to identify components for inclusion in a live attenuated tetravalent DENV vaccine
    • Durbin AP, Kirkpatrick BD, Pierce KK, Schmidt AC, Whitehead SS. 2011. Development and clinical evaluation of multiple investigational monovalent DENV vaccines to identify components for inclusion in a live attenuated tetravalent DENV vaccine. Vaccine 29:7242-50
    • (2011) Vaccine , vol.29 , pp. 7242-7250
    • Durbin, A.P.1    Kirkpatrick, B.D.2    Pierce, K.K.3    Schmidt, A.C.4    Whitehead, S.S.5
  • 54
    • 0035215425 scopus 로고    scopus 로고
    • A live attenuated recombinant dengue-4 virus vaccine candidate with restricted capacity for dissemination in mosquitoes and lack of transmission from vaccinees to mosquitoes
    • Troyer JM, Hanley KA, Whitehead SS, Strickman D, Karron RA, et al. 2001. A live attenuated recombinant dengue-4 virus vaccine candidate with restricted capacity for dissemination in mosquitoes and lack of transmission from vaccinees to mosquitoes. Am. J. Trop. Med. Hyg. 65:414-19
    • (2001) Am. J. Trop. Med. Hyg. , vol.65 , pp. 414-419
    • Troyer, J.M.1    Hanley, K.A.2    Whitehead, S.S.3    Strickman, D.4    Karron, R.A.5
  • 55
    • 0035211999 scopus 로고    scopus 로고
    • Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3'-untranslated region
    • Durbin AP, Karron RA, Sun W, Vaughn DW, Reynolds MJ, et al. 2001. Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3'-untranslated region. Am. J. Trop. Med. Hyg. 65:405-13
    • (2001) Am. J. Trop. Med. Hyg. , vol.65 , pp. 405-413
    • Durbin, A.P.1    Karron, R.A.2    Sun, W.3    Vaughn, D.W.4    Reynolds, M.J.5
  • 56
    • 84874264885 scopus 로고    scopus 로고
    • A single dose of any of four different live attenuated tetravalent dengue vaccines is safe and immunogenic in flavivirus-naive adults: A randomized, double-blind clinical trial
    • Durbin AP, Kirkpatrick BD, Pierce KK, Elwood D, Larsson CJ, et al. 2013. A single dose of any of four different live attenuated tetravalent dengue vaccines is safe and immunogenic in flavivirus-naive adults: a randomized, double-blind clinical trial. J. Infect. Dis. 207:957-65
    • (2013) J. Infect. Dis. , vol.207 , pp. 957-965
    • Durbin, A.P.1    Kirkpatrick, B.D.2    Pierce, K.K.3    Elwood, D.4    Larsson, C.J.5
  • 57
    • 0029916970 scopus 로고    scopus 로고
    • Testing of a dengue 2 liveattenuated vaccine (strain 16681 PDK 53) in ten American volunteers
    • Vaughn DW, Hoke CH Jr, Yoksan S, LaChance R, Innis BL, et al. 1996. Testing of a dengue 2 liveattenuated vaccine (strain 16681 PDK 53) in ten American volunteers. Vaccine 14:329-36
    • (1996) Vaccine , vol.14 , pp. 329-336
    • Vaughn, D.W.1    Hoke, C.H.2    Yoksan, S.3    Lachance, R.4    Innis, B.L.5
  • 58
    • 0034063918 scopus 로고    scopus 로고
    • Attenuationmarkers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3
    • Butrapet S, HuangCY, Pierro DJ, Bhamarapravati N, Gubler DJ, KinneyRM.2000. Attenuationmarkers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3. J. Virol. 74:3011-19
    • (2000) J. Virol. , vol.74 , pp. 3011-3019
    • Butrapet, S.1    Huang, C.Y.2    Pierro, D.J.3    Bhamarapravati, N.4    Gubler, D.J.5    Kinney, R.M.6
  • 59
    • 84878507105 scopus 로고    scopus 로고
    • Genetic and phenotypic characterization of manufacturing seeds for a tetravalent dengue vaccine (DENVax)
    • Huang CY, Kinney RM, Livengood JA, Bolling B, Arguello JJ, et al. 2013. Genetic and phenotypic characterization of manufacturing seeds for a tetravalent dengue vaccine (DENVax). PLoS Negl. Trop. Dis. 7:e2243
    • (2013) PLoS Negl. Trop. Dis. , vol.7 , pp. e2243
    • Huang, C.Y.1    Kinney, R.M.2    Livengood, J.A.3    Bolling, B.4    Arguello, J.J.5
  • 60
    • 80052410152 scopus 로고    scopus 로고
    • The development of recombinant subunit envelope-based vaccines to protect against dengue virus induced disease
    • Coller BA, Clements DE, Bett AJ, Sagar SL, Ter Meulen JH. 2011. The development of recombinant subunit envelope-based vaccines to protect against dengue virus induced disease. Vaccine 29:7267-75
    • (2011) Vaccine , vol.29 , pp. 7267-7275
    • Coller, B.A.1    Clements, D.E.2    Bett, A.J.3    Sagar, S.L.4    Ter Meulen, J.H.5
  • 61
    • 32344443602 scopus 로고    scopus 로고
    • Immunogenicity and safety of two live-attenuated tetravalent dengue vaccine formulations in healthy Australian adults
    • Kitchener S, Nissen M, Nasveld P, Forrat R, Yoksan S, et al. 2006. Immunogenicity and safety of two live-attenuated tetravalent dengue vaccine formulations in healthy Australian adults. Vaccine 24:1238-41
    • (2006) Vaccine , vol.24 , pp. 1238-1241
    • Kitchener, S.1    Nissen, M.2    Nasveld, P.3    Forrat, R.4    Yoksan, S.5
  • 62
    • 77649270249 scopus 로고    scopus 로고
    • Development of a recombinant tetravalent dengue virus vaccine: Immunogenicity and efficacy studies in mice and monkeys
    • Clements DE,Coller BA, LiebermanMM,Ogata S,WangG, et al. 2010. Development of a recombinant tetravalent dengue virus vaccine: immunogenicity and efficacy studies in mice and monkeys. Vaccine 28:2705-15
    • (2010) Vaccine , vol.28 , pp. 2705-2715
    • Clements, D.E.1    Coller, B.A.2    Lieberman, M.M.3    Ogata, S.4    Wang, G.5
  • 63
    • 80052404085 scopus 로고    scopus 로고
    • Development of dengue DNA vaccines
    • Danko JR, Beckett CG, Porter KR. 2011. Development of dengue DNA vaccines. Vaccine 29:7261-66
    • (2011) Vaccine , vol.29 , pp. 7261-7266
    • Danko, J.R.1    Beckett, C.G.2    Porter, K.R.3
  • 64
    • 0030928465 scopus 로고    scopus 로고
    • Inoculation of plasmids expressing the dengue-2 envelope gene elicit neutralizing antibodies in mice
    • Kochel T, Wu SJ, Raviprakash K, Hobart P, Hoffman S, et al. 1997. Inoculation of plasmids expressing the dengue-2 envelope gene elicit neutralizing antibodies in mice. Vaccine 15:547-52
    • (1997) Vaccine , vol.15 , pp. 547-552
    • Kochel, T.1    Wu, S.J.2    Raviprakash, K.3    Hobart, P.4    Hoffman, S.5
  • 65
    • 0031862714 scopus 로고    scopus 로고
    • Protective efficacy of a dengue 2 DNA vaccine in mice and the effect of CpG immuno-stimulatory motifs on antibody responses
    • Porter KR,KochelTJ,WuSJ, Raviprakash K, Phillips I,Hayes CG. 1998. Protective efficacy of a dengue 2 DNA vaccine in mice and the effect of CpG immuno-stimulatory motifs on antibody responses. Arch. Virol. 143:997-1003
    • (1998) Arch. Virol. , vol.143 , pp. 997-1003
    • Porter, K.R.1    Kochel, T.J.2    Wu, S.J.3    Raviprakash, K.4    Phillips, I.5    Hayes, C.G.6
  • 66
    • 0033990759 scopus 로고    scopus 로고
    • A DNA vaccine expressing dengue type 2 virus premembrane and envelope genes induces neutralizing antibody and memory B cells in mice
    • Konishi E, Yamaoka M, Kurane I, Mason PW. 2000. A DNA vaccine expressing dengue type 2 virus premembrane and envelope genes induces neutralizing antibody and memory B cells in mice. Vaccine 18:1133-39
    • (2000) Vaccine , vol.18 , pp. 1133-1139
    • Konishi, E.1    Yamaoka, M.2    Kurane, I.3    Mason, P.W.4
  • 67
    • 0035265843 scopus 로고    scopus 로고
    • Molecular organization of a recombinant subviral particle from tick-borne encephalitis virus
    • Ferlenghi I, Clarke M, Ruttan T, Allison SL, Schalich J, et al. 2001. Molecular organization of a recombinant subviral particle from tick-borne encephalitis virus. Mol. Cell 7:593-602
    • (2001) Mol. Cell , vol.7 , pp. 593-602
    • Ferlenghi, I.1    Clarke, M.2    Ruttan, T.3    Allison, S.L.4    Schalich, J.5
  • 68
    • 84862244480 scopus 로고    scopus 로고
    • Manipulation of immunodominant dengue virus e protein epitopes reduces potential antibody-dependent enhancement
    • Hughes HR, Crill WD, Chang GJ. 2012. Manipulation of immunodominant dengue virus E protein epitopes reduces potential antibody-dependent enhancement. Virol. J. 9:115
    • (2012) Virol. J. , vol.9 , pp. 115
    • Hughes, H.R.1    Crill, W.D.2    Chang, G.J.3
  • 69
    • 78751572962 scopus 로고    scopus 로고
    • Evaluation of a prototype dengue-1 DNA vaccine in a phase 1 clinical trial
    • Beckett CG, Tjaden J, Burgess T, Danko JR, Tamminga C, et al. 2011. Evaluation of a prototype dengue-1 DNA vaccine in a phase 1 clinical trial. Vaccine 29:960-68
    • (2011) Vaccine , vol.29 , pp. 960-968
    • Beckett, C.G.1    Tjaden, J.2    Burgess, T.3    Danko, J.R.4    Tamminga, C.5
  • 70
    • 84974727310 scopus 로고    scopus 로고
    • Flaviviruses
    • ed.DMKnipe,PMHowley, Philadelphia: LippincottWilliams & Wilkins. 6th ed
    • PiersonTC, DiamondMS. 2013. Flaviviruses. In Fields Virology, ed.DMKnipe,PMHowley, pp. 747-94. Philadelphia: LippincottWilliams & Wilkins. 6th ed.
    • (2013) Fields Virology , pp. 747-794
    • Pierson, T.C.1    Diamond, M.S.2
  • 71
    • 50849120046 scopus 로고    scopus 로고
    • Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: Implications for vaccine development
    • Pierson TC, Fremont DH, Kuhn RJ, Diamond MS. 2008. Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development. Cell Host Microbe 4:229-38
    • (2008) Cell Host Microbe , vol.4 , pp. 229-238
    • Pierson, T.C.1    Fremont, D.H.2    Kuhn, R.J.3    Diamond, M.S.4
  • 72
    • 0025037999 scopus 로고
    • Molecular evolution and distribution of dengue viruses type 1 and 2 in nature
    • Rico-Hesse R. 1990. Molecular evolution and distribution of dengue viruses type 1 and 2 in nature. Virology 174:479-93
    • (1990) Virology , vol.174 , pp. 479-493
    • Rico-Hesse, R.1
  • 73
    • 0037404062 scopus 로고    scopus 로고
    • The origin, emergence and evolutionary genetics of dengue virus
    • Holmes EC, Twiddy SS. 2003. The origin, emergence and evolutionary genetics of dengue virus. Infect. Genet. Evol. 3:19-28
    • (2003) Infect. Genet. Evol. , vol.3 , pp. 19-28
    • Holmes, E.C.1    Twiddy, S.S.2
  • 74
    • 77957192264 scopus 로고    scopus 로고
    • Genotype specific neutralization and protection by antibodies against dengue virus type 3
    • Brien JD, Austin SK, Sukupolvi-Petty S, O'Brien KM, Johnson S, et al. 2010. Genotype specific neutralization and protection by antibodies against dengue virus type 3. J. Virol. 84:10630-43
    • (2010) J. Virol. , vol.84 , pp. 10630-10643
    • Brien, J.D.1    Austin, S.K.2    Sukupolvi-Petty, S.3    O'brien, K.M.4    Johnson, S.5
  • 76
    • 70350347088 scopus 로고    scopus 로고
    • Structural basis for the preferential binding of immature flaviviruses by a fusion-loop specific antibody
    • Cherrier MV, Kaufmann B, Nybakken GE, Lok SM, Warren JT, et al. 2009. Structural basis for the preferential binding of immature flaviviruses by a fusion-loop specific antibody. EMBO J. 28:3269-76
    • (2009) EMBO J. , vol.28 , pp. 3269-3276
    • Cherrier, M.V.1    Kaufmann, B.2    Nybakken, G.E.3    Lok, S.M.4    Warren, J.T.5
  • 77
    • 77954972691 scopus 로고    scopus 로고
    • Influence of pr-M cleavage on the heterogeneity of extracellular dengue virus particles
    • Junjhon J, Edwards TJ, Utaipat U, Bowman VD, Holdaway HA, et al. 2010. Influence of pr-M cleavage on the heterogeneity of extracellular dengue virus particles. J. Virol. 84:8353-58
    • (2010) J. Virol. , vol.84 , pp. 8353-8358
    • Junjhon, J.1    Edwards, T.J.2    Utaipat, U.3    Bowman, V.D.4    Holdaway, H.A.5
  • 78
    • 84859500348 scopus 로고    scopus 로고
    • Degrees of maturity: The complex structure and biology of flaviviruses
    • Pierson TC, DiamondMS. 2012. Degrees of maturity: the complex structure and biology of flaviviruses. Curr. Opin. Virol. 2:168-75
    • (2012) Curr. Opin. Virol. , vol.2 , pp. 168-175
    • Pierson, T.C.1    Diamond, M.S.2
  • 79
    • 80655143443 scopus 로고    scopus 로고
    • The infectivity of prM-containing partially mature West Nile virus does not require the activity of cellular furin-like proteases
    • Mukherjee S, Lin TY, Dowd KA, Manhart CJ, Pierson TC. 2011. The infectivity of prM-containing partially mature West Nile virus does not require the activity of cellular furin-like proteases. J. Virol. 85:12067-72
    • (2011) J. Virol. , vol.85 , pp. 12067-12072
    • Mukherjee, S.1    Lin, T.Y.2    Dowd, K.A.3    Manhart, C.J.4    Pierson, T.C.5
  • 80
    • 45849095234 scopus 로고    scopus 로고
    • How do proteins interact?
    • Boehr DD, Wright PE. 2008. How do proteins interact? Science 320:1429-30
    • (2008) Science , vol.320 , pp. 1429-1430
    • Boehr, D.D.1    Wright, P.E.2
  • 81
    • 84876549863 scopus 로고    scopus 로고
    • Assembly, stability and dynamics of virus capsids
    • Mateu MG. 2013. Assembly, stability and dynamics of virus capsids. Arch. Biochem. Biophys. 531:65-79
    • (2013) Arch. Biochem. Biophys. , vol.531 , pp. 65-79
    • Mateu, M.G.1
  • 83
    • 84868111424 scopus 로고    scopus 로고
    • Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope
    • Austin SK, Dowd KA, Shrestha B, Nelson CA, Edeling MA, et al. 2012. Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope. PLoS Pathog. 8:e1002930
    • (2012) PLoS Pathog. , vol.8 , pp. e1002930
    • Austin, S.K.1    Dowd, K.A.2    Shrestha, B.3    Nelson, C.A.4    Edeling, M.A.5
  • 86
    • 79959812241 scopus 로고    scopus 로고
    • A dynamic landscape for antibody binding modulates antibody-mediated neutralization ofWest Nile virus
    • Dowd KA, Jost CA, Durbin AP, Whitehead SS, Pierson TC. 2011. A dynamic landscape for antibody binding modulates antibody-mediated neutralization ofWest Nile virus. PLoS Pathog. 7:e1002111
    • (2011) PLoS Pathog. , vol.7 , pp. e1002111
    • Dowd, K.A.1    Jost, C.A.2    Durbin, A.P.3    Whitehead, S.S.4    Pierson, T.C.5
  • 89
    • 0031985001 scopus 로고    scopus 로고
    • Evidence of viral capsid dynamics using limited proteolysis and mass spectrometry
    • Bothner B, Dong XF, Bibbs L, Johnson JE, Siuzdak G. 1998. Evidence of viral capsid dynamics using limited proteolysis and mass spectrometry. J. Biol. Chem. 273:673-76
    • (1998) J. Biol. Chem. , vol.273 , pp. 673-676
    • Bothner, B.1    Dong, X.F.2    Bibbs, L.3    Johnson, J.E.4    Siuzdak, G.5
  • 90
    • 67650453769 scopus 로고    scopus 로고
    • Antibodies to the buried N terminus of rhinovirus VP4 exhibit cross-serotypic neutralization
    • Katpally U, Fu TM, Freed DC, Casimiro DR, Smith TJ. 2009. Antibodies to the buried N terminus of rhinovirus VP4 exhibit cross-serotypic neutralization. J. Virol. 83:7040-48
    • (2009) J. Virol. , vol.83 , pp. 7040-7048
    • Katpally, U.1    Fu, T.M.2    Freed, D.C.3    Casimiro, D.R.4    Smith, T.J.5
  • 91
    • 84901992641 scopus 로고    scopus 로고
    • The mechanism and significance of cell type-dependent neutralization of flaviviruses
    • In press
    • Mukherjee S, Dowd KA, Manhart CJ, Ledgerwood JE, Durbin AP, et al. 2014. The mechanism and significance of cell type-dependent neutralization of flaviviruses. J. Virol. In press. doi: 10.1128/JVI.03690-13
    • (2014) J. Virol.
    • Mukherjee, S.1    Dowd, K.A.2    Manhart, C.J.3    Ledgerwood, J.E.4    Durbin, A.P.5
  • 92
    • 0028070971 scopus 로고
    • Antibody-dependent enhancement of infection and the pathogenesis of viral disease
    • Morens DM. 1994. Antibody-dependent enhancement of infection and the pathogenesis of viral disease. Clin. Infect. Dis. 19:500-12
    • (1994) Clin. Infect. Dis. , vol.19 , pp. 500-512
    • Morens, D.M.1
  • 93
    • 84879685472 scopus 로고    scopus 로고
    • Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: An historical perspective and role of antibody-dependent enhancement of infection
    • Guzman MG, Alvarez M, Halstead SB. 2013. Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: an historical perspective and role of antibody-dependent enhancement of infection. Arch. Virol. 158:1445-59
    • (2013) Arch. Virol. , vol.158 , pp. 1445-1459
    • Guzman, M.G.1    Alvarez, M.2    Halstead, S.B.3
  • 94
    • 80355133197 scopus 로고    scopus 로고
    • Infection and activation of human peripheral blood monocytes by dengue viruses through the mechanism of antibody-dependent enhancement
    • Sun P, Bauza K, Pal S, Liang Z,Wu SJ, et al. 2011. Infection and activation of human peripheral blood monocytes by dengue viruses through the mechanism of antibody-dependent enhancement. Virology 421:245-52
    • (2011) Virology , vol.421 , pp. 245-252
    • Sun, P.1    Bauza, K.2    Pal, S.3    Liang, Z.4    Wu, S.J.5
  • 95
    • 78650735911 scopus 로고    scopus 로고
    • Humanantibodies against dengue enhance dengue viral infectivity without suppressing type i interferon secretion in primary human monocytes
    • KouZ,Lim JY, Beltramello M, QuinnM,ChenH, et al. 2011.Humanantibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes. Virology 410:240-47
    • (2011) Virology , vol.410 , pp. 240-247
    • Kou, Z.1    Lim, J.Y.2    Beltramello, M.3    Quinn, M.4    Chen, H.5
  • 96
    • 34147133789 scopus 로고    scopus 로고
    • The stoichiometry of antibodymediated neutralization and enhancement ofWest Nile virus infection
    • Pierson TC, Xu Q, Nelson S, Oliphant T, Nybakken GE, et al. 2007. The stoichiometry of antibodymediated neutralization and enhancement ofWest Nile virus infection. Cell Host Microbe 1:135-45
    • (2007) Cell Host Microbe , vol.1 , pp. 135-145
    • Pierson, T.C.1    Xu, Q.2    Nelson, S.3    Oliphant, T.4    Nybakken, G.E.5
  • 97
    • 84857855597 scopus 로고    scopus 로고
    • Dengue virus infection-enhancing activity in serum samples with neutralizing activity as determined by using FcγR-expressing cells
    • MoiML, Lim CK, Chua KB, Takasaki T, Kurane I. 2012. Dengue virus infection-enhancing activity in serum samples with neutralizing activity as determined by using FcγR-expressing cells. PLoS Negl. Trop. Dis. 6:e1536
    • (2012) PLoS Negl. Trop. Dis. , vol.6 , pp. e1536
    • Moi, M.L.1    Lim, C.K.2    Chua, K.B.3    Takasaki, T.4    Kurane, I.5
  • 98
    • 33749454503 scopus 로고    scopus 로고
    • Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human FcγRIA (CD64) or FcγRIIA (CD32)
    • Rodrigo WW, Jin X, Blackley SD, Rose RC, Schlesinger JJ. 2006. Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human FcγRIA (CD64) or FcγRIIA (CD32). J. Virol. 80:10128-38
    • (2006) J. Virol. , vol.80 , pp. 10128-10138
    • Rodrigo, W.W.1    Jin, X.2    Blackley, S.D.3    Rose, R.C.4    Schlesinger, J.J.5
  • 99
    • 70449095877 scopus 로고    scopus 로고
    • Dengue virus neutralization is modulated by IgG antibody subclass and Fcγreceptor subtype
    • Rodrigo WW, Block OK, Lane C, Sukupolvi-Petty S, Goncalvez AP, et al. 2009. Dengue virus neutralization is modulated by IgG antibody subclass and Fcγreceptor subtype. Virology 394:175-82
    • (2009) Virology , vol.394 , pp. 175-182
    • Rodrigo, W.W.1    Block, O.K.2    Lane, C.3    Sukupolvi-Petty, S.4    Goncalvez, A.P.5
  • 100
    • 84878061100 scopus 로고    scopus 로고
    • Dengue virus neutralization in cells expressing Fcγreceptors
    • Chawla T, Chan KR, Zhang SL, Tan HC, Lim AP, et al. 2013. Dengue virus neutralization in cells expressing Fcγreceptors. PLoS ONE 8:e65231
    • (2013) PLoS ONE , vol.8 , pp. e65231
    • Chawla, T.1    Chan, K.R.2    Zhang, S.L.3    Tan, H.C.4    Lim, A.P.5
  • 102
    • 77956605864 scopus 로고    scopus 로고
    • The human immune response to dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity
    • Beltramello M, Williams KL, Simmons CP, Macagno A, Simonelli L, et al. 2010. The human immune response to dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe 8:271-83
    • (2010) Cell Host Microbe , vol.8 , pp. 271-283
    • Beltramello, M.1    Williams, K.L.2    Simmons, C.P.3    Macagno, A.4    Simonelli, L.5
  • 104
    • 36349025968 scopus 로고    scopus 로고
    • Comparison of plaque-and flow cytometry-based methods for measuring dengue virus neutralization
    • Kraus AA, Messer W, Haymore LB, de Silva AM. 2007. Comparison of plaque-and flow cytometry-based methods for measuring dengue virus neutralization. J. Clin. Microbiol. 45:3777-80
    • (2007) J. Clin. Microbiol. , vol.45 , pp. 3777-3780
    • Kraus, A.A.1    Messer, W.2    Haymore, L.B.3    De Silva, A.M.4
  • 106
    • 0027180431 scopus 로고
    • The Fc portion of antibody to yellow fever virus NS1 is a determinant of protection against YF encephalitis in mice
    • Schlesinger JJ, Foltzer M, Chapman S. 1993. The Fc portion of antibody to yellow fever virus NS1 is a determinant of protection against YF encephalitis in mice. Virology 192:132-41
    • (1993) Virology , vol.192 , pp. 132-141
    • Schlesinger, J.J.1    Foltzer, M.2    Chapman, S.3
  • 107
    • 36749028784 scopus 로고    scopus 로고
    • Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specificmanner
    • Mehlhop E, Ansarah-Sobrinho C, Johnson S, EngleM, Fremont DH, et al. 2007. Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specificmanner. Cell Host Microbe 2:417-26
    • (2007) Cell Host Microbe , vol.2 , pp. 417-426
    • Mehlhop, E.1    Ansarah-Sobrinho, C.2    Johnson, S.3    Engle, M.4    Fremont, D.H.5
  • 108
    • 72649088588 scopus 로고    scopus 로고
    • Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization ofWest Nile virus
    • Mehlhop E, Nelson S, Jost CA, Gorlatov S, Johnson S, et al. 2009. Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization ofWest Nile virus. Cell Host Microbe 6:381-91
    • (2009) Cell Host Microbe , vol.6 , pp. 381-391
    • Mehlhop, E.1    Nelson, S.2    Jost, C.A.3    Gorlatov, S.4    Johnson, S.5
  • 109
    • 21044448356 scopus 로고    scopus 로고
    • Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus
    • Oliphant T, Engle M, Nybakken G, Doane C, Johnson S, et al. 2005. Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus. Nat. Med. 11:522-30
    • (2005) Nat. Med. , vol.11 , pp. 522-530
    • Oliphant, T.1    Engle, M.2    Nybakken, G.3    Doane, C.4    Johnson, S.5
  • 110
    • 80655146256 scopus 로고    scopus 로고
    • Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fc-γreceptor and complement-dependent effector mechanisms
    • Vogt MR, Dowd KA, Engle M, Tesh RB, Johnson S, et al. 2011. Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fc-γreceptor and complement-dependent effector mechanisms. J. Virol. 22:11567-80
    • (2011) J. Virol. , vol.22 , pp. 11567-11580
    • Vogt, M.R.1    Dowd, K.A.2    Engle, M.3    Tesh, R.B.4    Johnson, S.5
  • 111
    • 34548176969 scopus 로고    scopus 로고
    • Antibody recognition of cell surface-associated NS1 triggers Fc-γ receptor mediated phagocytosis and clearance of WNV infected cells
    • Chung KM, Thompson BS, Fremont DH, Diamond MS. 2007. Antibody recognition of cell surface-associated NS1 triggers Fc-γ receptor mediated phagocytosis and clearance of WNV infected cells. J. Virol. 81:9551-55
    • (2007) J. Virol. , vol.81 , pp. 9551-9555
    • Chung, K.M.1    Thompson, B.S.2    Fremont, D.H.3    Diamond, M.S.4
  • 112
    • 37849009012 scopus 로고    scopus 로고
    • Infection-enhancing and-neutralizing activities of mouse monoclonal antibodies against dengue type 2 and 4 viruses are controlled by complement levels
    • Yamanaka A, Kosugi S, Konishi E. 2008. Infection-enhancing and-neutralizing activities of mouse monoclonal antibodies against dengue type 2 and 4 viruses are controlled by complement levels. J. Virol. 82:927-37
    • (2008) J. Virol. , vol.82 , pp. 927-937
    • Yamanaka, A.1    Kosugi, S.2    Konishi, E.3
  • 113
    • 34047221846 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity mediated by plasma obtained before secondary dengue virus infections: Potential involvement in early control of viral replication
    • Laoprasopwattana K, LibratyDH, Endy TP, Nisalak A, Chunsuttiwat S, et al. 2007. Antibody-dependent cellular cytotoxicity mediated by plasma obtained before secondary dengue virus infections: potential involvement in early control of viral replication. J. Infect. Dis. 195:1108-16
    • (2007) J. Infect. Dis. , vol.195 , pp. 1108-1116
    • Laoprasopwattana, K.1    Libraty, D.H.2    Endy, T.P.3    Nisalak, A.4    Chunsuttiwat, S.5
  • 114
    • 0032994359 scopus 로고    scopus 로고
    • Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashion
    • FlamandM,Megret F,Mathieu M, Lepault J,Rey FA,DeubelV. 1999. Dengue virus type 1 nonstructural glycoprotein NS1 is secreted from mammalian cells as a soluble hexamer in a glycosylation-dependent fashion. J. Virol. 73:6104-10
    • (1999) J. Virol. , vol.73 , pp. 6104-6110
    • Flamand, M.1    Megret, F.2    Mathieu, M.3    Lepault, J.4    Rey, F.A.5    Deubel, V.6
  • 115
    • 0036164518 scopus 로고    scopus 로고
    • Enzyme-linked immunosorbent assay specific to dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections
    • Alcon S, Talarmin A, Debruyne M, Falconar A, Deubel V, Flamand M. 2002. Enzyme-linked immunosorbent assay specific to dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections. J. Clin. Microbiol. 40:376-81
    • (2002) J. Clin. Microbiol. , vol.40 , pp. 376-381
    • Alcon, S.1    Talarmin, A.2    Debruyne, M.3    Falconar, A.4    Deubel, V.5    Flamand, M.6
  • 116
    • 0037108657 scopus 로고    scopus 로고
    • High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever
    • Libraty DH, Young PR, Pickering D, Endy TP, Kalayanarooj S, et al. 2002. High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever. J. Infect. Dis. 186:1165-68
    • (2002) J. Infect. Dis. , vol.186 , pp. 1165-1168
    • Libraty, D.H.1    Young, P.R.2    Pickering, D.3    Endy, T.P.4    Kalayanarooj, S.5
  • 117
    • 0034088137 scopus 로고    scopus 로고
    • An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients
    • Young PR, Hilditch PA, Bletchly C, HalloranW. 2000. An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients. J. Clin. Microbiol. 38:1053-57
    • (2000) J. Clin. Microbiol. , vol.38 , pp. 1053-1057
    • Young, P.R.1    Hilditch, P.A.2    Bletchly, C.3    Halloran, W.4
  • 118
    • 0025997355 scopus 로고
    • Recombinant baculoviruses expressing yellow fever virus e and NS1 proteins elicit protective immunity in mice
    • Despres P, Dietrich J, Girard M, Bouloy M. 1991. Recombinant baculoviruses expressing yellow fever virus E and NS1 proteins elicit protective immunity in mice. J. Gen. Virol. 72:2811-16
    • (1991) J. Gen. Virol. , vol.72 , pp. 2811-2816
    • Despres, P.1    Dietrich, J.2    Girard, M.3    Bouloy, M.4
  • 119
    • 0023030604 scopus 로고
    • Protection against yellow fever in monkeys by immunization with yellow fever virus nonstructural protein NS1
    • Schlesinger JJ, BrandrissMW, Cropp CB,Monath TP. 1986. Protection against yellow fever in monkeys by immunization with yellow fever virus nonstructural protein NS1. J. Virol. 60:1153-55
    • (1986) J. Virol. , vol.60 , pp. 1153-1155
    • Schlesinger, J.J.1    Brandriss, M.W.2    Cropp, C.B.3    Monath, T.P.4
  • 120
    • 0025182390 scopus 로고
    • Protection of mice against yellow fever virus encephalitis by immunization with a vaccinia virus recombinant encoding the yellow fever virus non-structural proteins, NS1, NS2a and NS2b
    • Putnak JR, Schlesinger JJ. 1990. Protection of mice against yellow fever virus encephalitis by immunization with a vaccinia virus recombinant encoding the yellow fever virus non-structural proteins, NS1, NS2a and NS2b. J. Gen. Virol. 71:1697-702
    • (1990) J. Gen. Virol. , vol.71 , pp. 1697-1702
    • Putnak, J.R.1    Schlesinger, J.J.2
  • 121
    • 0023784098 scopus 로고
    • Synergistic interactions of anti-NS1 monoclonal antibodies protect passively immunized mice from lethal challenge with dengue 2 virus
    • Henchal EA, Henchal LS, Schlesinger JJ. 1988. Synergistic interactions of anti-NS1 monoclonal antibodies protect passively immunized mice from lethal challenge with dengue 2 virus. J. Gen. Virol. 69:2101-7
    • (1988) J. Gen. Virol. , vol.69 , pp. 2101-2107
    • Henchal, E.A.1    Henchal, L.S.2    Schlesinger, J.J.3
  • 122
    • 0025102185 scopus 로고
    • Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis
    • Falgout B, Bray M, Schlesinger JJ, Lai CJ. 1990. Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis. J. Virol. 64:4356-63
    • (1990) J. Virol. , vol.64 , pp. 4356-4363
    • Falgout, B.1    Bray, M.2    Schlesinger, J.J.3    Lai, C.J.4
  • 123
    • 31144442443 scopus 로고    scopus 로고
    • Antibodies against West Nile virus non-structural (NS)-1 protein prevent lethal infection through Fcγreceptor-dependent and independent mechanisms
    • Chung KM, Nybakken GE, Thompson BS, Engle MJ, Marri A, et al. 2006. Antibodies against West Nile virus non-structural (NS)-1 protein prevent lethal infection through Fcγreceptor-dependent and independent mechanisms. J. Virol. 80:1340-51
    • (2006) J. Virol. , vol.80 , pp. 1340-1351
    • Chung, K.M.1    Nybakken, G.E.2    Thompson, B.S.3    Engle, M.J.4    Marri, A.5
  • 124
    • 84894277002 scopus 로고    scopus 로고
    • Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system
    • Akey DL, Brown WC, Dutta S, Konwerski J, Jose J, et al. 2014. Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system. Science 343:881-85
    • (2014) Science , vol.343 , pp. 881-885
    • Akey, D.L.1    Brown, W.C.2    Dutta, S.3    Konwerski, J.4    Jose, J.5
  • 125
    • 84896535479 scopus 로고    scopus 로고
    • Structural basis of flavivirus NS1 assembly and antibody recognition
    • EdelingMA, DiamondMS, FremontDH. 2014. Structural basis of flavivirus NS1 assembly and antibody recognition. Proc. Natl. Acad. Sci. USA 111:4285-90
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 4285-4290
    • Edeling, M.A.1    Diamond, M.S.2    Fremont, D.H.3
  • 127
    • 77958487137 scopus 로고    scopus 로고
    • Plasticity and heterogeneity in the generation of memory Bcells and long-lived plasma cells: The influence of germinal center interactions and dynamics
    • Good-Jacobson KL, Shlomchik MJ. 2010. Plasticity and heterogeneity in the generation of memory Bcells and long-lived plasma cells: the influence of germinal center interactions and dynamics. J. Immunol. 185:3117-25
    • (2010) J. Immunol. , vol.185 , pp. 3117-3125
    • Good-Jacobson, K.L.1    Shlomchik, M.J.2
  • 128
    • 0031571728 scopus 로고    scopus 로고
    • Early neutralizing antibody response against mouse mammary tumor virus: Critical role of viral infection and superantigenreactive T cells
    • Luther SA, Maillard I, Luthi F, Scarpellino L, Diggelmann H, Acha-Orbea H. 1997. Early neutralizing antibody response against mouse mammary tumor virus: critical role of viral infection and superantigenreactive T cells. J. Immunol. 159:2807-14
    • (1997) J. Immunol. , vol.159 , pp. 2807-2814
    • Luther, S.A.1    Maillard, I.2    Luthi, F.3    Scarpellino, L.4    Diggelmann, H.5    Acha-Orbea, H.6
  • 129
    • 0347593991 scopus 로고    scopus 로고
    • A critical role for induced IgM in the protection against West Nile virus infection
    • Diamond MS, Sitati E, Friend L, Shrestha B, Higgs S, Engle M. 2003. A critical role for induced IgM in the protection against West Nile virus infection. J. Exp. Med. 198:1853-62
    • (2003) J. Exp. Med. , vol.198 , pp. 1853-1862
    • Diamond, M.S.1    Sitati, E.2    Friend, L.3    Shrestha, B.4    Higgs, S.5    Engle, M.6
  • 130
    • 84857963464 scopus 로고    scopus 로고
    • Rapid and massive virusspecific plasmablast responses during acute dengue virus infection in humans
    • Wrammert J, Onlamoon N, Akondy RS, Perng GC, Polsrila K, et al. 2012. Rapid and massive virusspecific plasmablast responses during acute dengue virus infection in humans. J. Virol. 86:2911-18
    • (2012) J. Virol. , vol.86 , pp. 2911-2918
    • Wrammert, J.1    Onlamoon, N.2    Akondy, R.S.3    Perng, G.C.4    Polsrila, K.5
  • 131
    • 84859200054 scopus 로고    scopus 로고
    • Dominant cross-reactive B cell response during secondary acute dengue virus infection in humans
    • Zompi S, MontoyaM, PohlMO, Balmaseda A,Harris E. 2012. Dominant cross-reactive B cell response during secondary acute dengue virus infection in humans. PLoS Negl. Trop. Dis. 6:e1568
    • (2012) PLoS Negl. Trop. Dis. , vol.6 , pp. e1568
    • Zompi, S.1    Montoya, M.2    Pohl, M.O.3    Balmaseda, A.4    Harris, E.5
  • 132
    • 0035873727 scopus 로고    scopus 로고
    • Extrafollicular plasmablast B cells play a key role in carrying retroviral infection to peripheral organs
    • Finke D, Baribaud F, Diggelmann H, Acha-Orbea H. 2001. Extrafollicular plasmablast B cells play a key role in carrying retroviral infection to peripheral organs. J. Immunol. 166:6266-75
    • (2001) J. Immunol. , vol.166 , pp. 6266-6275
    • Finke, D.1    Baribaud, F.2    Diggelmann, H.3    Acha-Orbea, H.4
  • 133
    • 0026060620 scopus 로고
    • Intraclonal generation of antibody mutants in germinal centres
    • Jacob J, Kelsoe G, Rajewsky K,Weiss U. 1991. Intraclonal generation of antibody mutants in germinal centres. Nature 354:389-92
    • (1991) Nature , vol.354 , pp. 389-392
    • Jacob, J.1    Kelsoe, G.2    Rajewsky, K.3    Weiss, U.4
  • 134
    • 1842405362 scopus 로고    scopus 로고
    • Lifetime of plasma cells in the bone marrow
    • Manz RA, Thiel A, Radbruch A. 1997. Lifetime of plasma cells in the bone marrow. Nature 388:133-34
    • (1997) Nature , vol.388 , pp. 133-134
    • Manz, R.A.1    Thiel, A.2    Radbruch, A.3
  • 135
    • 0028796357 scopus 로고
    • Bone marrow is a major site of long-term antibody production after acute viral infection
    • SlifkaMK,Matloubian M, AhmedR. 1995. Bone marrow is a major site of long-term antibody production after acute viral infection. J. Virol. 69:1895-902
    • (1995) J. Virol. , vol.69 , pp. 1895-1902
    • Slifka, M.K.1    Matloubian, M.2    Ahmed, R.3
  • 136
  • 137
    • 84055207530 scopus 로고    scopus 로고
    • Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection
    • Balakrishnan T, Bela-Ong DB, Toh YX, FlamandM, Devi S, et al. 2011. Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection. PLoS ONE 6:e29430
    • (2011) PLoS ONE , vol.6 , pp. e29430
    • Balakrishnan, T.1    Bela-Ong, D.B.2    Toh, Y.X.3    Flamand, M.4    Devi, S.5
  • 138
    • 84255191089 scopus 로고    scopus 로고
    • The human antibody response to dengue virus infection
    • WahalaWM,SilvaAM. 2011. The human antibody response to dengue virus infection. Viruses 3:2374-95
    • (2011) Viruses , vol.3 , pp. 2374-2395
    • Wahala, W.M.1    Silva, A.M.2
  • 139
    • 79961053789 scopus 로고    scopus 로고
    • Ligation of Fcγ receptor IIB inhibits antibody-dependent enhancement of dengue virus infection
    • Chan KR, Zhang SL, Tan HC, Chan YK, Chow A, et al. 2011. Ligation of Fcγ receptor IIB inhibits antibody-dependent enhancement of dengue virus infection. Proc. Natl. Acad. Sci. USA 108:12479-84
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 12479-12484
    • Chan, K.R.1    Zhang, S.L.2    Tan, H.C.3    Chan, Y.K.4    Chow, A.5
  • 141
    • 84855512128 scopus 로고    scopus 로고
    • Memory B cells but not long-lived plasma cells possess antigen specificities for viral escape mutants
    • Purtha WE, Tedder TF, Johnson S, Bhattacharya D, Diamond MS. 2011. Memory B cells but not long-lived plasma cells possess antigen specificities for viral escape mutants. J. Exp. Med. 208:2599-606
    • (2011) J. Exp. Med. , vol.208 , pp. 2599-2606
    • Purtha, W.E.1    Tedder, T.F.2    Johnson, S.3    Bhattacharya, D.4    Diamond, M.S.5
  • 142
    • 84883597357 scopus 로고    scopus 로고
    • Identifying protective dengue vaccines: Guide to mastering an empirical process
    • Halstead SB. 2013. Identifying protective dengue vaccines: guide to mastering an empirical process. Vaccine 31:4501-7
    • (2013) Vaccine , vol.31 , pp. 4501-4507
    • Halstead, S.B.1
  • 143
    • 78149481379 scopus 로고    scopus 로고
    • CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination
    • Yauch LE, Prestwood TR, May MM, Morar MM, Zellweger RM, et al. 2010. CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination. J. Immunol. 185:5405-16
    • (2010) J. Immunol. , vol.185 , pp. 5405-5416
    • Yauch, L.E.1    Prestwood, T.R.2    May, M.M.3    Morar, M.M.4    Zellweger, R.M.5
  • 145
    • 4544229451 scopus 로고    scopus 로고
    • Dengue-specific CD8+ T cells have both protective and pathogenic roles in dengue virus infection
    • An J, Zhou DS, Zhang JL, Morida H, Wang JL, Yasui K. 2004. Dengue-specific CD8+ T cells have both protective and pathogenic roles in dengue virus infection. Immunol. Lett. 95:167-74
    • (2004) Immunol. Lett. , vol.95 , pp. 167-174
    • An, J.1    Zhou, D.S.2    Zhang, J.L.3    Morida, H.4    Wang, J.L.5    Yasui, K.6
  • 146
    • 70349514677 scopus 로고    scopus 로고
    • Recombinant nucleocapsid-like particles from dengue-2 virus induce protective CD4+ and CD8+ cells against viral encephalitis in mice
    • Gil L, Lopez C, Lazo L, Valdes I, Marcos E, et al. 2009. Recombinant nucleocapsid-like particles from dengue-2 virus induce protective CD4+ and CD8+ cells against viral encephalitis in mice. Int. Immunol. 21:1175-83
    • (2009) Int. Immunol. , vol.21 , pp. 1175-1183
    • Gil, L.1    Lopez, C.2    Lazo, L.3    Valdes, I.4    Marcos, E.5
  • 147
    • 77957344542 scopus 로고    scopus 로고
    • Nucleocapsid-like particles of dengue-2 virus enhance the immune response against a recombinant protein of dengue-4 virus
    • Lazo L, Gil L, Lopez C, Valdes I, Marcos E, et al. 2010. Nucleocapsid-like particles of dengue-2 virus enhance the immune response against a recombinant protein of dengue-4 virus. Arch. Virol. 155:1587-95
    • (2010) Arch. Virol. , vol.155 , pp. 1587-1595
    • Lazo, L.1    Gil, L.2    Lopez, C.3    Valdes, I.4    Marcos, E.5
  • 148
    • 79960839437 scopus 로고    scopus 로고
    • A human challenge model for dengue infection reveals a possible protective role for sustained interferon γlevels during the acute phase of illness
    • Gunther VJ, Putnak R, Eckels KH, Mammen MP, Scherer JM, et al. 2011. A human challenge model for dengue infection reveals a possible protective role for sustained interferon γlevels during the acute phase of illness. Vaccine 29:3895-904
    • (2011) Vaccine , vol.29 , pp. 3895-3904
    • Gunther, V.J.1    Putnak, R.2    Eckels, K.H.3    Mammen, M.P.4    Scherer, J.M.5
  • 150
    • 84878446213 scopus 로고    scopus 로고
    • Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells
    • Weiskopf D, Angelo MA, de Azeredo EL, Sidney J, Greenbaum JA, et al. 2013. Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells. Proc. Natl. Acad. Sci. USA 110:E2046-53
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. E2046-E2053
    • Weiskopf, D.1    Angelo, M.A.2    De Azeredo, E.L.3    Sidney, J.4    Greenbaum, J.A.5
  • 152
    • 79960835805 scopus 로고    scopus 로고
    • Immunity to dengue virus: A tale of original antigenic sin and tropical cytokine storms
    • Rothman AL. 2011. Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms. Nat. Rev. Immunol. 11:532-43
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 532-543
    • Rothman, A.L.1
  • 153
    • 77953646070 scopus 로고    scopus 로고
    • Timing of CD8+ T cell responses in relation to commencement of capillary leakage in children with dengue
    • Dung NT, Duyen HT, Thuy NT, Ngoc TV, Chau NV, et al. 2010. Timing of CD8+ T cell responses in relation to commencement of capillary leakage in children with dengue. J. Immunol. 184:7281-87
    • (2010) J. Immunol. , vol.184 , pp. 7281-7287
    • Dung, N.T.1    Duyen, H.T.2    Thuy, N.T.3    Ngoc, T.V.4    Chau, N.V.5
  • 154
    • 84860164276 scopus 로고    scopus 로고
    • Cross-reactivity and expansion of dengue-specific T cells during acute primary and secondary infections in humans
    • Friberg H, Bashyam H, Toyosaki-Maeda T, Potts JA, Greenough T, et al. 2011. Cross-reactivity and expansion of dengue-specific T cells during acute primary and secondary infections in humans. Sci. Rep. 1:51
    • (2011) Sci. Rep. , vol.1 , pp. 51
    • Friberg, H.1    Bashyam, H.2    Toyosaki-Maeda, T.3    Potts, J.A.4    Greenough, T.5


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