Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 44, 2010, Pages 18950-18955

  Kaufmann, Bärbel ^a   Vogt, Matthew R ^b   Goudsmit, Jaap ^c   Holdaway, Heather A ^a   Aksyuk, Anastasia A ^a   Chipman, Paul R ^a   Kuhn, Richard J ^a   Diamond, Michael S ^b   Rossmann, Michael G ^a  

^a PURDUE UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c CRUCELL HOLLAND BV   (Netherlands)

Author keywords

Antibody; Cryoelectron microscopy; Flavivirus

Indexed keywords

CR 4354; EPITOPE; GLYCOPROTEIN; HOMODIMER; MONOCLONAL ANTIBODY; MONOMER; UNCLASSIFIED DRUG; VIRUS PROTEIN;

BINDING SITE; CONFERENCE PAPER; CROSS LINKING; CRYOELECTRON MICROSCOPY; ENDOSOME; FLAVIVIRUS INFECTION; HUMAN; HUMORAL IMMUNITY; LIFE CYCLE; NONHUMAN; PH; PRIORITY JOURNAL; VIRUS NEUTRALIZATION; WEST NILE FLAVIVIRUS;

FLAVIVIRUS; WEST NILE VIRUS;

EID: 78650495030     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1011036107     Document Type: Article

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