Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope

PLoS Pathogens

Volumn 8, Issue 10, 2012, Pages

  Austin, S Kyle ^a   Dowd, Kimberly A ^b   Shrestha, Bimmi ^a   Nelson, Christopher A ^a   Edeling, Melissa A ^a   Johnson, Syd ^c   Pierson, Theodore C ^b   Diamond, Michael S ^a   Fremont, Daved H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c Analytical Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; NEUTRALIZING ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ARTICLE; BINDING AFFINITY; CONFORMATION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; DENGUE VIRUS 1; GENOTYPE; HUMAN; HUMAN CELL; MOLECULAR DOCKING; PROTEIN DOMAIN; VIRION; VIRUS NEUTRALIZATION;

ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; BINDING SITES, ANTIBODY; DENGUE; DENGUE VIRUS; EPITOPE MAPPING; EPITOPES; HUMANS; PROTEIN STRUCTURE, TERTIARY; VIRAL ENVELOPE PROTEINS;

DENGUE VIRUS;

EID: 84868111424     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002930     Document Type: Article

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