TonEBP modulates the protective effect of taurine in ischemia-induced cytotoxicity in cardiomyocytes

Cell Death and Disease

Volumn 6, Issue 12, 2015, Pages

  Yang, Y J ^a   Han, Y Y ^a   Chen, K ^a   Zhang, Y ^a   Liu, X ^a   Li, S ^a   Wang, K Q ^a   Ge, J B ^a   Liu, W ^a   Zuo, J ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

TAURINE; TRANSCRIPTION FACTOR NFAT;

ANIMAL; CARDIAC MUSCLE CELL; CYTOLOGY; DRUG EFFECTS; MALE; METABOLISM; MYOCARDIAL ISCHEMIA; PATHOLOGY; RANDOMIZATION; SPRAGUE DAWLEY RAT;

ANIMALS; MALE; MYOCARDIAL ISCHEMIA; MYOCYTES, CARDIAC; NFATC TRANSCRIPTION FACTORS; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY; TAURINE;

EID: 85016677131     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/CDDIS.2015.372     Document Type: Article

References (36)

1. Van de Werf F, Crea F. The year in cardiology 2014: acute coronary syndromes. Eur Heart J 2015; 36: 342–346.
2. Voors AA, Ruschitzka F. The year in cardiology: heart failure 2014. Eur Heart J 2015; 36: 421–424.
3. Erbel R, Wijns W. The year in cardiology 2013: coronary intervention. Eur Heart J 2014; 35: 313–320.
4. Hayes KC. A review on the biological function of taurine. Nutr Rev 1976; 34: 161–165.
5. Wojcik OP, Koenig KL, Zeleniuch-Jacquotte A, Costa M, Chen Y. The potential protective effects of taurine on coronary heart disease. Atherosclerosis 2010; 208: 19–25.
6. Schaffer SW, Azuma J. Review: myocardial physiological effects of taurine and their significance. Adv Exp Med Biol 1992; 315: 105–120.
7. Schaffer SW, Jong CJ, Ito T, Azuma J. Effect of taurine on ischemia-reperfusion injury. Amino Acids 2014; 46: 21–30.
8. Schaffer SW, Jong CJ, Ramila KC, Azuma J. Physiological roles of taurine in heart and muscle. J Biomed Sci 2010; 17(Suppl 1): S2.
9. Das J, Roy A, Sil PC. Mechanism of the protective action of taurine in toxin and drug induced organ pathophysiology and diabetic complications: a review. Food Func 2012; 3: 1251–1264.
10. Ito T, Fujio Y, Hirata M, Takatani T, Matsuda T, Muraoka S et al. Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells. Biochem J 2004; 382(Pt 1): 177–182.
11. Ito T, Kimura Y, Uozumi Y, Takai M, Muraoka S, Matsuda T et al. Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy. J Mol Cell Cardiol 2008; 44: 927–937.
12. Yang Y, Zhang Y, Liu X, Zuo J, Wang K, Liu W et al. Exogenous taurine attenuates mitochondrial oxidative stress and endoplasmic reticulum stress in rat cardiomyocytes. Acta Biochimica et Biophysica Sinica (Shanghai) 2013; 45: 359–367.
13. Zhang Y, Yang L, Yang YJ, Liu XY, Jia JG, Qian JY et al. Low-dose taurine upregulates taurine transporter expression in acute myocardial ischemia. Int J Mol Med 2013; 31: 817–824.
14. Ito T, Oishi S, Takai M, Kimura Y, Uozumi Y, Fujio Y et al. Cardiac and skeletal muscle abnormality in taurine transporter-knockout mice. J Biomed Sci 2010; 17 (Suppl 1): S20.
15. Kendler BS. Supplemental conditionally essential nutrients in cardiovascular disease therapy. J Cardiovasc Nurs 2006; 21: 9–16.
16. Yamashita A, Singh SK, Kawate T, Jin Y, Gouaux E. Crystal structure of a bacterial homologue of Na+/Cl–dependent neurotransmitter transporters. Nature 2005; 437: 215–223.
17. Ho SN. The role of NFAT5/TonEBP in establishing an optimal intracellular environment. Arch Biochem Biophys 2003; 413: 151–157.
18. Woo SK, Lee SD, Kwon HM. TonEBP transcriptional activator in the cellular response to increased osmolality. Pflugers Archiv Eur J Physiol 2002; 444: 579–585.
19. Kennergren C, Mantovani V, Lonnroth P, Nystrom B, Berglin E, Hamberger A. Extracellular amino acids as markers of myocardial ischemia during cardioplegic heart arrest. Cardiology 1999; 91: 31–40.
20. Yang Y, Yang L, Zhang Y, Gu X, Xu D, Fang F et al. Taurine detected using high-resolution magic angle spinning (1)H nuclear magnetic resonance: a potential indicator of early myocardial infarction. Exp Ther Med 2013; 5: 683–688.
21. Modi P, Suleiman MS, Reeves BC, Pawade A, Parry AJ, Angelini GD et al. Free amino acids in hearts of pediatric patients with congenital heart disease: the effects of cyanosis, age, and pathology. Ann Thorac Surg 2006; 81: 943–949.
22. Han X, Chesney RW. Stress-responsive gene TauT and acute kidney injury. J Biomed Sci 2010; 17(Suppl 1): S28.
23. Ito T, Fujio Y, Schaffer SW, Azuma J. Involvement of transcriptional factor TonEBP in the regulation of the taurine transporter in the cardiomyocyte. Adv Exp Med Biol 2009; 643: 523–532.
24. Kempson SA, Beck JA, Lammers PE, Gens JS, Montrose MH. Membrane insertion of betaine/GABA transporter during hypertonic stress correlates with nuclear accumulation of TonEBP. Biochimica et Biophysica Acta 2005; 1712: 71–80.
25. Tong EH, Guo JJ, Huang AL, Liu H, Hu CD, Chung SS et al. Regulation of nucleocytoplasmic trafficking of transcription factor OREBP/TonEBP/NFAT5. J Biol Chem 2006; 281: 23870–23879.
26. Gallazzini M, Heussler GE, Kunin M, Izumi Y, Burg MB, Ferraris JD. High NaCl-induced activation of CDK5 increases phosphorylation of the osmoprotective transcription factor TonEBP/OREBP at threonine 135, which contributes to its rapid nuclear localization. Mol Biol Cell 2011; 22: 703–714.
27. Loyher ML, Mutin M, Woo SK, Kwon HM, Tappaz ML. Transcription factor tonicity-responsive enhancer-binding protein (TonEBP) which transactivates osmoprotective genes is expressed and upregulated following acute systemic hypertonicity in neurons in brain. Neuroscience 2004; 124: 89–104.
28. Hsin YH, Tang CH, Lai HT, Lee TH. The role of TonEBP in regulation of AAD expression and dopamine production in renal proximal tubule cells upon hypertonic challenge. Biochem Biophys Res Commun 2011; 414: 598–603.
29. Kojima R, Randall JD, Ito E, Manshio H, Suzuki Y, Gullans SR. Regulation of expression of the stress response gene, Osp94: identification of the tonicity response element and intracellular signalling pathways. Biocheml J 2004; 380(Pt 3): 783–794.
30. Tsai TT, Danielson KG, Guttapalli A, Oguz E, Albert TJ, Shapiro IM et al. TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc. J Biol Chem 2006; 281: 25416–25424.
31. Nakayama Y, Peng T, Sands JM, Bagnasco SM. The TonE/TonEBP pathway mediates tonicity-responsive regulation of UT-A urea transporter expression. J Biol Chem 2000; 275: 38275–38280.
32. Zhou X, Ferraris JD, Cai Q, Agarwal A, Burg MB. Increased reactive oxygen species contribute to high NaCl-induced activation of the osmoregulatory transcription factor TonEBP/OREBP. Am J Physiol Renal Physiol 2005; 289: F377–F385.
33. Kim SJ, Kim H, Park J, Chung I, Kwon HM, Choi WS et al. Tonicity response element binding protein associated with neuronal cell death in the experimental diabetic retinopathy. Int J Ophthalmol 2014; 7: 935–940.
34. Wang H, Ferraris JD, Klein JD, Sands JM, Burg MB, Zhou X. PKC-alpha contributes to high NaCl-induced activation of NFAT5 (TonEBP/OREBP) through MAPK ERK1/2. Am J Physiol Renal Physiol 2015; 308: F140–F148.
35. Cui M, Tang X, Christian WV, Yoon Y, Tieu K. Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. J Biol Chem 2010; 285: 11740–11752.
36. Liu FT, Chen Y, Yang YJ, Yang L, Yu M, Zhao J et al. Involvement of mortalin/GRP75/ mthsp70 in the mitochondrial impairments induced by A53T mutant alpha-synuclein. Brain Res 2015; 1604: 52–61.