PKC-α contributes to high NaCl-induced activation of NFAT5 (TonEBP/OREBP) through MAPK ERK1/2

American Journal of Physiology - Renal Physiology

Volumn 308, Issue 2, 2015, Pages F140-F148

  Wang, Hong ^a   Ferraris, Joan D ^b   Klein, Janet D ^c   Sands, Jeff M ^c   Burg, Maurice B ^b   Zhou, Xiaoming ^a  

^a Uniformed Services University of the Health Sciences   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hypertonicity; Inner medulla; Nuclear factor of activated T cells 5; Osmotic response element binding protein; Serine 591 phosphorylated Src homology 2 domaincontaining phosphatase 1; Src homology 2 domain containing phosphatase 1; Tonicity responsive enhancer binding protein; Urinary concentration

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE C ALPHA; SMALL INTERFERING RNA; SODIUM CHLORIDE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT5; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; NUCLEAR FACTOR OF ACTIVATED T CELLS 5;

ANIMAL TISSUE; ARTICLE; ENZYME PHOSPHORYLATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; INTERSTITIAL FLUID; KIDNEY CORTEX; KIDNEY MEDULLA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; C57BL MOUSE; ENZYMOLOGY; KIDNEY; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION; EMBRYO; ENZYME ACTIVATION; IMMUNOPRECIPITATION; KIDNEY INNER MEDULLA; PROTEIN PHOSPHORYLATION; URINE OSMOLALITY; WESTERN BLOTTING;

ANIMALS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEK293 CELLS; HUMANS; KIDNEY; MAP KINASE SIGNALING SYSTEM; MICE, INBRED C57BL; NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; SODIUM CHLORIDE;

EID: 84920993725     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00471.2014     Document Type: Article

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