Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy

Journal of Molecular and Cellular Cardiology

Volumn 44, Issue 5, 2008, Pages 927-937

  Ito, Takashi ^a   Kimura, Yasushi ^a   Uozumi, Yoriko ^a   Takai, Mika ^a   Muraoka, Satoko ^a   Matsuda, Takahisa ^a   Ueki, Kei ^b   Yoshiyama, Minoru ^c   Ikawa, Masahito ^d   Okabe, Masaru ^d   Schaffer, Stephen W ^e   Fujio, Yasushi ^a   Azuma, Junichi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b SRL INC   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Atrophy; Cardiomyopathy; Cell volume; Heart; Mitochondrial defect; Osmoregulation; Taurine; Taurine transporter; Transgenic mice

Indexed keywords

CALGRANULIN B; CALVASCULIN; MITOCHONDRIAL PROTEIN; TAURINE TRANSPORTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; ELECTROCARDIOGRAM; GENE DISRUPTION; HEART FAILURE; HEART MUSCLE CELL; MOUSE; NONHUMAN; OSMOREGULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING;

ANIMALS; ATROPHY; CARDIOMYOPATHIES; CELL SIZE; DOWN-REGULATION; GENE TARGETING; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MUSCLE, SKELETAL; MYOCARDIUM; MYOCYTES, CARDIAC; MYOFIBRILS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SIZE; OSMOTIC PRESSURE; PHYSICAL CONDITIONING, ANIMAL; PHYSICAL ENDURANCE; SUCCINATE DEHYDROGENASE; TAURINE;

MUS; MUS MUSCULUS;

EID: 42749093925     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2008.03.001     Document Type: Article

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