The role of TonEBP in regulation of AAD expression and dopamine production in renal proximal tubule cells upon hypertonic challenge

Biochemical and Biophysical Research Communications

Volumn 414, Issue 3, 2011, Pages 598-603

  Hsin, Yi Hong ^a   Tang, Cheng Hao ^b   Lai, Hsing Tzu ^a   Lee, Tsug Han ^a,c  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b NATIONAL MUSEUM OF MARINE BIOLOGY AND AQUARIUM   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

AAD; Hypertonic stress; TonEBP; Transcriptional regulation

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; AROMATIC LEVO AMINO ACID DECARBOXYLASE; DOPAMINE; HYPERTONIC SOLUTION; ISOTONIC SOLUTION; MEMBRANE PROTEIN; PEPTIDES AND PROTEINS; SHORT HAIRPIN RNA; SMIT PROTEIN; TAURINE TRANSPORTER; TONEBP PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CELL NUCLEUS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOPAMINE METABOLISM; ENZYME ACTIVATION; ENZYME REGULATION; EPITHELIUM CELL; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; HYPEROSMOTIC STRESS; KIDNEY PROXIMAL TUBULE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CELLS, CULTURED; DOPA DECARBOXYLASE; DOPAMINE; HUMANS; KIDNEY TUBULES, PROXIMAL; SALINE SOLUTION, HYPERTONIC; SODIUM-POTASSIUM-EXCHANGING ATPASE; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS;

EID: 80054911565     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.09.128     Document Type: Article

References (32)

1. Burg M.B., Ferraris J.D., Dmitrieva N.I. Cellular response to hyperosmotic stresses. Physiol. Rev. 2007, 87:1441-1474.
2. Handler J.S., Kwon H.M. Cell and molecular biology of organic osmolyte accumulation in hypertonic renal cells. Nephron 2001, 87:106-110.
3. Rim J.S., Atta M.G., Dahl S.C., Berry G.T., Handler J.S., Kwon H.M. Transcription of the sodium/myo-inositol cotransporter gene is regulated by multiple tonicity-responsive enhancers spread over 50kilobase pairs in the 5'-flanking region. J. Biol. Chem. 1998, 273:20615-20621.
4. Miyakawa H., Woo S.K., Chen C.P., Dahl S.C., Handler J.S., Kwon H.M. Cis- and trans-acting factors regulating transcription of the BGT1 gene in response to hypertonicity. Am. J. Physiol. 1998, 274:F753-F761.
5. Lopez-Rodriguez C., Aramburu J., Jin L., Rakeman A.S., Michino M., Rao A. Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress. Immunity 2001, 15:47-58.
6. Gallazzini M., Karim Z., Bichara M. Regulation of ROMK (Kir 1.1) channel expression in kidney thick ascending limb by hypertonicity: role of TonEBP and MAPK pathways. Nephron Physiol. 2006, 104:126-135.
7. Kultz D., Csonka L. What sets the TonE during osmotic stress?. Proc. Natl. Acad. Sci. USA 1999, 96:1814-1816.
8. +-ATPase activity and endocytosis by modulating the recruitment of adaptor protein 2 and clathrin. Proc. Natl. Acad. Sci. USA 2000, 97:3242-3247.
9. Carey R.M. Theodore cooper lecture: renal dopamine system: paracrine regulator of sodium homeostasis and blood pressure. Hypertension 2001, 38:297-302.
10. Hayashi M., Yamaji Y., Kitajima W., Saruta T. Effects of high salt intake on dopamine production in rat kidney. Am. J. Physiol. 1991, 260:E675-E679.
11. Alper R.H., Moore K.E. Injection of hypertonic saline or mannitol accelerates the dehydration-induced activation of dopamine synthesis in the neurointermediate lobe of the rat hypophysis. Neuroendocrinology 1982, 35:469-474.
12. Sakai M., Fujii T., Karasawa N., Arai R., Nagatsu I. Enhanced expression of tyrosine hydroxylase and aromatic l-amino acid decarboxylase in cerebellar Purkinje cells of mouse after hyperosmotic stimuli. Neurosci. Lett. 1995, 194:142-144.
13. Kwon M.S., Lee S.D., Kim J.A., Colla E., Choi Y.J., Suh P.G., Kwon H.M. Novel nuclear localization signal regulated by ambient tonicity in vertebrates. J. Biol. Chem. 2008, 283:22400-22409.
14. Nakayama Y., Peng T., Sands J.M., Bagnasco S.M. The TonE/TonEBP pathway mediates tonicity-responsive regulation of UT-A urea transporter expression. J. Biol. Chem. 2000, 275:38275-38280.
15. +-ATPase responses and its potential role in triggering ion reabsorption in kidneys for homeostasis of marine euryhaline milkfish (Chanos chanos) when acclimated to hypotonic fresh water. J. Comp. Physiol. B 2010, 180:813-824.
16. Zhang Z., Cohen D.M. NaCl but not urea activates p38 and jun kinase in mIMCD3 murine inner medullary cells. Am. J. Physiol 1996, 271:F1234-F1238.
17. Kojima R., Taniguchi H., Tsuzuki A., Nakamura K., Sakakura Y., Ito M. Hypertonicity-induced expression of monocyte chemoattractant protein-1 through a novel cis-acting element and MAPK signaling pathways. J. Immunol. 2010, 184:5253-5262.
18. Pedemonte C.H., Efendiev R., Bertorello A.M. Inhibition of Na, K-ATPase by dopamine in proximal tubule epithelial cells. Semin. Nephrol. 2005, 25:322-327.
19. Jeon U.S., Kim J.A., Sheen M.R., Kwon H.M. How tonicity regulates genes: story of TonEBP transcriptional activator. Acta Physiol. (Oxf) 2006, 187:241-247.
20. Woo S.K., Lee S.D., Kwon H.M. TonEBP transcriptional activator in the cellular response to increased osmolality. Pflugers Arch. 2002, 444:579-585.
21. Miyakawa H., Woo S.K., Dahl S.C., Handler J.S., Kwon H.M. Tonicity-responsive enhancer binding protein, A rel-like protein that stimulates transcription in response to hypertonicity. Proc. Natl. Acad. Sci. USA 1999, 96:2538-2542.
22. Dahl S.C., Handler J.S., Kwon H.M. Hypertonicity-induced phosphorylation and nuclear localization of the transcription factor TonEBP. Am. J. Physiol. Cell Physiol. 2001, 280:C248-C253.
23. Favale N.O., Casali C.I., Lepera L.G., Pescio L.G., Fernandez-Tome M.C. Hypertonic induction of COX2 expression requires TonEBP/NFAT5 in renal epithelial cells. Biochem. Biophys. Res. Commun. 2009, 381:301-305.
24. Navarro P., Chiong M., Volkwein K., Moraga F., Ocaranza M.P., Jalil J.E., Lim S.W., Kim J.A., Kwon H.M., Lavandero S. Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes. Biochem. Biophys. Res. Commun. 2008, 372:326-330.
25. Pestana M., Jardim H., Correia F., Vieira-Coelho M.A., Soares-da-Silva P. Renal dopaminergic mechanisms in renal parenchymal diseases and hypertension. Nephrol. Dial. Transplant. 2001, 16(Suppl. 1):53-59.
26. Vieira-Coelho M.A., Hussain T., Kansra V., Serrao M.P., Guimaraes J.T., Pestana M., Soares-Da-Silva P., Lokhandwala M.F. Aging, high salt intake, and renal dopaminergic activity in Fischer 344 rats. Hypertension 1999, 34:666-672.
27. Dawson R., Felheim R., Phillips M.I. Characterization of the synthesis and release of dopamine in LLC-PK1 cells. Ren. Physiol. Biochem. 1994, 17:85-100.
28. Ko B.C., Ruepp B., Bohren K.M., Gabbay K.H., Chung S.S. Identification and characterization of multiple osmotic response sequences in the human aldose reductase gene. J. Biol. Chem. 1997, 272:16431-16437.
29. Hussain T., Lokhandwala M.F. Renal dopamine receptors and hypertension. Exp. Biol. Med. (Maywood.) 2003, 228:134-142.
30. Pinho M.J., Gomes P., Serrao M.P., Bonifacio M.J., Soares-da-Silva P. Organ-specific overexpression of renal LAT2 and enhanced tubular L-DOPA uptake precede the onset of hypertension. Hypertension 2003, 42:613-618.
31. Zeng C., Sanada H., Watanabe H., Eisner G.M., Felder R.A., Jose P.A. Functional genomics of the dopaminergic system in hypertension. Physiol. Genomics 2004, 19:233-246.
32. +-ATPase endocytosis. J. Biol. Chem. 1998, 273:8814-8819.