Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment

Genome Biology

Volumn 18, Issue 1, 2017, Pages

  Wang, Tina ^a   Tsui, Brian ^a,e   Kreisberg, Jason F ^a   Robertson, Neil A ^b   Gross, Andrew M ^a,e   Yu, Michael Ku ^a,e   Carter, Hannah ^a,e   Brown Borg, Holly M ^c   Adams, Peter D ^b,d   Ideker, Trey ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^d BURNHAM INSTITUTE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; DNA methylation; Epigenetic aging; Epigenomics

Indexed keywords

RAPAMYCIN;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DWARFISM; EPIGENETICS; FEMALE; GENOME; HUMAN; HUMAN TISSUE; LIFE EXTENSION; LONGEVITY; MALE; METHYLOME; MOUSE; NONHUMAN; ANIMAL; CLUSTER ANALYSIS; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETIC EPIGENESIS; GENETICS; LIVER; METABOLISM; PROCEDURES;

AGING; ANIMALS; CALORIC RESTRICTION; CLUSTER ANALYSIS; CPG ISLANDS; DNA METHYLATION; DWARFISM; EPIGENESIS, GENETIC; EPIGENOMICS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; LIVER; LONGEVITY; MALE; MICE; SIROLIMUS;

EID: 85016465042     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-017-1186-2     Document Type: Article

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