Single-cell genome-wide bisulfite sequencing uncovers extensive heterogeneity in the mouse liver methylome

Genome Biology

Volumn 17, Issue 1, 2016, Pages

  Gravina, Silvia ^a,b   Dong, Xiao ^a   Yu, Bo ^a,c   Vijg, Jan ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b ILLUMINA INC   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Epigenetic instability; Epivariations; Single cell DNA methylomics; Single cell epigenomics

Indexed keywords

5 METHYLCYTOSINE; HISTONE H3;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENETIC HETEROGENEITY; GENOMICS; INTRON; LIVER; LIVER CELL; MALE; METHYLOMICS; MOUSE; NONHUMAN; PROMOTER REGION; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS; SINGLE CELL WHOLE GENOME BISULFITE SEQUENCING; SOMATIC MUTATION; ANIMAL; GENETICS; GENOME; HIGH THROUGHPUT SEQUENCING; METABOLISM; MUTATION; PROCEDURES;

5-METHYLCYTOSINE; ANIMALS; CPG ISLANDS; DNA METHYLATION; GENETIC HETEROGENEITY; GENOME; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; LIVER; MICE; MUTATION; PROMOTER REGIONS, GENETIC; SINGLE-CELL ANALYSIS;

EID: 84977525598     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-1011-3     Document Type: Article

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