-
1
-
-
84931573012
-
Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling
-
Ma YS, Hsiao YP, Lin JH, Hsu SC, Chueh FS, Weng SW, Lai KC, Lin JG and Chung JG: Crude extract of Rheum palmatum L inhibits migration and invasion of LS1034 human colon cancer cells acts through the inhibition of matrix metalloproteinase-2/-9 by MAPK signaling. Environ Toxicol 30: 852-863, 2014.
-
(2014)
Environ Toxicol
, vol.30
, pp. 852-863
-
-
Ma, Y.S.1
Hsiao, Y.P.2
Lin, J.H.3
Hsu, S.C.4
Chueh, F.S.5
Weng, S.W.6
Lai, K.C.7
Lin, J.G.8
Chung, J.G.9
-
2
-
-
79952113311
-
Surgical and combined treatment of patients with metastatic liver and lymph nodes invasion by colorectal cancer
-
(in Russian)
-
Patiutko IuI, Pylev AL, Sagaidak IV, Poliakov AN, Chuchuev ES, Abgarian MG and Shishkina NA: Surgical and combined treatment of patients with metastatic liver and lymph nodes invasion by colorectal cancer. Khirurgiia (Mosk) 7: 49-54, 2010 (in Russian).
-
(2010)
Khirurgiia (Mosk)
, vol.7
, pp. 49-54
-
-
Iui, P.1
Pylev, A.L.2
Sagaidak, I.V.3
Poliakov, A.N.4
Chuchuev, E.S.5
Abgarian, M.G.6
Shishkina, N.A.7
-
3
-
-
84883645320
-
Baicalein inhibits the invasion and metastatic capabilities of hepatocellular carcinoma cells via down-regulation of the ERK pathway
-
Chen K, Zhang S, Ji Y, Li J, An P, Ren H, Liang R, Yang J and Li Z : Baicalein inhibits the invasion and metastatic capabilities of hepatocellular carcinoma cells via down-regulation of the ERK pathway. PLoS One 8: e72927, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e72927
-
-
Chen, K.1
Zhang, S.2
Ji, Y.3
Li, J.4
An, P.5
Ren, H.6
Liang, R.7
Yang, J.8
Li, Z.9
-
4
-
-
78650424066
-
Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
-
G ialeli C, Theocharis AD and Karamanos NK: Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting. FEBS J 278: 16-27, 2011.
-
(2011)
FEBS J
, vol.278
, pp. 16-27
-
-
Gialeli, C.1
Theocharis, A.D.2
Karamanos, N.K.3
-
5
-
-
0033590636
-
Constitutive activation of the 41-/43-kDa mitogen-Activated protein kinase signaling pathway in human tumors
-
Hoshino R, Chatani Y, Yamori T, Tsuruo T, Oka H, Yoshida O, Shimada Y, Ari-i S, Wada H, Fujimoto J, et al: Constitutive activation of the 41-/43-kDa mitogen-Activated protein kinase signaling pathway in human tumors. Oncogene 18: 813-822, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 813-822
-
-
Hoshino, R.1
Chatani, Y.2
Yamori, T.3
Tsuruo, T.4
Oka, H.5
Yoshida, O.6
Shimada, Y.7
Ari-I, S.8
Wada, H.9
Fujimoto, J.10
-
6
-
-
84895926310
-
9-Hydroxypheophorbide α-mediated photodynamic therapy induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in Hep-2 cells via ROS-mediated suppression of the ERK pathway
-
Z hang H, Shen B, Swinarska JT, Li W, Xiao K and He P: 9-Hydroxypheophorbide α-mediated photodynamic therapy induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in Hep-2 cells via ROS-mediated suppression of the ERK pathway. Photodiagn Photodyn Ther 11: 55-62, 2014.
-
(2014)
Photodiagn Photodyn Ther
, vol.11
, pp. 55-62
-
-
Zhang, H.1
Shen, B.2
Swinarska, J.T.3
Li, W.4
Xiao, K.5
He, P.6
-
7
-
-
79955977302
-
High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells
-
Kress TR, Raabe T and Feller SM: High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells. Cell Commun Signal 8: 1, 2010.
-
(2010)
Cell Commun Signal
, vol.8
, pp. 1
-
-
Kress, T.R.1
Raabe, T.2
Feller, S.M.3
-
8
-
-
0345357221
-
The ERK pathway involves positive and negative regulations of HT-29 colorectal cancer cell growth by extracellular zinc
-
Park KS, Lee NG, Lee KH, Seo JT and Choi KY: The ERK pathway involves positive and negative regulations of HT-29 colorectal cancer cell growth by extracellular zinc. Am J Physiol Gastrointest Liver Physiol 285: G1181-G1188, 2003.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.285
, pp. G1181-G1188
-
-
Park, K.S.1
Lee, N.G.2
Lee, K.H.3
Seo, J.T.4
Choi, K.Y.5
-
9
-
-
84899575323
-
Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells
-
Kim HC, Kim YS, Oh HW, Kim K, Oh SS, Kim JT, Kim BY, Lee SJ, Choe YK, Kim DH, et al: Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells. Oncotarget 5: 519-529, 2014.
-
(2014)
Oncotarget
, vol.5
, pp. 519-529
-
-
Kim, H.C.1
Kim, Y.S.2
Oh, H.W.3
Kim, K.4
Oh, S.S.5
Kim, J.T.6
Kim, B.Y.7
Lee, S.J.8
Choe, Y.K.9
Kim, D.H.10
-
10
-
-
84890062212
-
Targeting the ERK pathway reduces liver metastasis of Smad4-inactivated colorectal cancer
-
Ai X, Wu Y, Zhang W, Zhang Z, Jin G, Zhao J, Yu J, Lin Y, Zhang W, Liang H, et al: Targeting the ERK pathway reduces liver metastasis of Smad4-inactivated colorectal cancer. Cancer Biol Ther 14: 1059-1067, 2013.
-
(2013)
Cancer Biol Ther
, vol.14
, pp. 1059-1067
-
-
Ai, X.1
Wu, Y.2
Zhang, W.3
Zhang, Z.4
Jin, G.5
Zhao, J.6
Yu, J.7
Lin, Y.8
Zhang, W.9
Liang, H.10
-
11
-
-
77956226747
-
Flavonoid baicalein suppresses adhesion, migration and invasion of MDA-MB-231 human breast cancer cells
-
Wang L, Ling Y, Chen Y, Li CL, Feng F, You QD, Lu N and Guo QL: Flavonoid baicalein suppresses adhesion, migration and invasion of MDA-MB-231 human breast cancer cells. Cancer Lett 297: 42-48, 2010.
-
(2010)
Cancer Lett
, vol.297
, pp. 42-48
-
-
Wang, L.1
Ling, Y.2
Chen, Y.3
Li, C.L.4
Feng, F.5
You, Q.D.6
Lu, N.7
Guo, Q.L.8
-
12
-
-
84885042534
-
Baicalein, an active component of Scutellaria baicalensis Georgi, induces apoptosis in human colon cancer cells and prevents AOM/DSS-induced colon cancer in mice
-
Kim DH, Hossain MA, Kang YJ, Jang JY, Lee YJ, Im E, Yoon JH, Kim HS, Chung HY and Kim ND: Baicalein, an active component of Scutellaria baicalensis Georgi, induces apoptosis in human colon cancer cells and prevents AOM/DSS-induced colon cancer in mice. Int J Oncol 43: 1652-1658, 2013.
-
(2013)
Int J Oncol
, vol.43
, pp. 1652-1658
-
-
Kim, D.H.1
Hossain, M.A.2
Kang, Y.J.3
Jang, J.Y.4
Lee, Y.J.5
Im, E.6
Yoon, J.H.7
Kim, H.S.8
Chung, H.Y.9
Kim, N.D.10
-
13
-
-
84875540393
-
Inhibitory effect of baicalin and baicalein on ovarian cancer cells
-
Chen J, Li Z, Chen AY, Ye X, Luo H, Rankin GO and Chen YC: Inhibitory effect of baicalin and baicalein on ovarian cancer cells. Int J Mol Sci 14: 6012-6025, 2013.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 6012-6025
-
-
Chen, J.1
Li, Z.2
Chen, A.Y.3
Ye, X.4
Luo, H.5
Rankin, G.O.6
Chen, Y.C.7
-
14
-
-
84873873444
-
Baicalein induces apoptosis via a mitochondrialdependent caspase activation pathway in T24 bladder cancer cells
-
Li HL, Zhang S, Wang Y, Liang RR, Li J, An P, Wang ZM, Yang J and Li ZF: Baicalein induces apoptosis via a mitochondrialdependent caspase activation pathway in T24 bladder cancer cells. Mol Med Rep 7: 266-270, 2013.
-
(2013)
Mol Med Rep
, vol.7
, pp. 266-270
-
-
Li, H.L.1
Zhang, S.2
Wang, Y.3
Liang, R.R.4
Li, J.5
An, P.6
Wang, Z.M.7
Yang, J.8
Li, Z.F.9
-
15
-
-
84865006776
-
Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling
-
Liang RR, Zhang S, Qi JA, Wang ZD, Li J, Liu PJ, Huang C, Le XF, Yang J and Li ZF: Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling. Int J Oncol 41: 969-978, 2012.
-
(2012)
Int J Oncol
, vol.41
, pp. 969-978
-
-
Liang, R.R.1
Zhang, S.2
Qi, J.A.3
Wang, Z.D.4
Li, J.5
Liu, P.J.6
Huang, C.7
Le Yang, X.F.J.8
Li, Z.F.9
-
16
-
-
84896528654
-
Baicalein reduces the invasion of glioma cells via reducing the activity of p38 signaling pathway
-
Z hang Z, Lv J, Lei X, Li S, Zhang Y, Meng L, Xue R and Li Z: Baicalein reduces the invasion of glioma cells via reducing the activity of p38 signaling pathway. PLoS One 9: e90318, 2014.
-
(2014)
PLoS One
, vol.9
, pp. e90318
-
-
Zhang, Z.1
Lv, J.2
Lei, X.3
Li, S.4
Zhang, Y.5
Meng, L.6
Xue, R.7
Li, Z.8
-
17
-
-
84860518210
-
Baicalein inhibits pulmonary carcinogenesisassociated inflammation and interferes with COX-2 MMP-2 and MMP-9 expressions in-vivo
-
Chandrashekar N, Selvamani A, Subramanian R, Pandi A and Thiruvengadam D: Baicalein inhibits pulmonary carcinogenesisassociated inflammation and interferes with COX-2, MMP-2 and MMP-9 expressions in-vivo. Toxicol Appl Pharmacol 261: 10-21, 2012.
-
(2012)
Toxicol Appl Pharmacol
, vol.261
, pp. 10-21
-
-
Chandrashekar, N.1
Selvamani, A.2
Subramanian, R.3
Pandi, A.4
Thiruvengadam, D.5
-
18
-
-
84455193326
-
Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A431 cells
-
Wu B, Li J, Huang D, Wang W, Chen Y, Liao Y, Tang X, Xie H and Tang F: Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A431 cells. BMC Cancer 11: 527, 2011.
-
(2011)
BMC Cancer
, vol.11
, pp. 527
-
-
Wu, B.1
Li, J.2
Huang, D.3
Wang, W.4
Chen, Y.5
Liao, Y.6
Tang, X.7
Xie, H.8
Tang, F.9
-
19
-
-
76649142108
-
Chrysanthemum indicum ethanolic extract inhibits invasion of hepatocellular carcinoma via regulation of MMP/TIMP balance as therapeutic target
-
Wang ZD, Huang C, Li ZF, Yang J, Li BH, Liang RR, Dai ZJ and Liu ZW: Chrysanthemum indicum ethanolic extract inhibits invasion of hepatocellular carcinoma via regulation of MMP/TIMP balance as therapeutic target. Oncol Rep 23: 413-421, 2010.
-
(2010)
Oncol Rep
, vol.23
, pp. 413-421
-
-
Wang, Z.D.1
Huang, C.2
Li, Z.F.3
Yang, J.4
Li, B.H.5
Liang, R.R.6
Dai, Z.J.7
Liu, Z.W.8
-
20
-
-
84908201003
-
P120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line
-
Organ SL, Hai J, Radulovich N, Marshall CB, Leung L, Sasazuki T, Shirasawa S, Zhu CQ, Navab R, Ikura M, et al: p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line. PLoS One 9: e86103, 2014.
-
(2014)
PLoS One
, vol.9
, pp. e86103
-
-
Organ, S.L.1
Hai, J.2
Radulovich, N.3
Marshall, C.B.4
Leung, L.5
Sasazuki, T.6
Shirasawa, S.7
Zhu, C.Q.8
Navab, R.9
Ikura, M.10
-
21
-
-
60549108926
-
N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1
-
Laezza C, Caruso MG, Gentile T, Notarnicola M, Malfitano AM, Di Matola T, Messa C, Gazzerro P and Bifulco M: N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1. Int J Cancer 124: 1322-1329, 2009.
-
(2009)
Int J Cancer
, vol.124
, pp. 1322-1329
-
-
Laezza, C.1
Caruso, M.G.2
Gentile, T.3
Notarnicola, M.4
Malfitano, A.M.5
Di Matola, T.6
Messa, C.7
Gazzerro, P.8
Bifulco, M.9
-
22
-
-
0037379768
-
Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1
-
Shida D, Kitayama J, Yamaguchi H, Okaji Y, Tsuno NH, Watanabe T, Takuwa Y and Nagawa H: Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1. Cancer Res 63: 1706-1711, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 1706-1711
-
-
Shida, D.1
Kitayama, J.2
Yamaguchi, H.3
Okaji, Y.4
Tsuno, N.H.5
Watanabe, T.6
Takuwa, Y.7
Nagawa, H.8
-
23
-
-
85016421028
-
Free-B-Ring flavonoids as potential lead compounds for colon cancer therapy
-
Ibrahim A, Sobeh M, Ismail A, Alaa A, Sheashaa H, Sobh M and Badria F: Free-B-Ring flavonoids as potential lead compounds for colon cancer therapy. Mol Clin Oncol 2: 581-585, 2014.
-
(2014)
Mol Clin Oncol
, vol.2
, pp. 581-585
-
-
Ibrahim, A.1
Sobeh, M.2
Ismail, A.3
Alaa, A.4
Sheashaa, H.5
Sobh, M.6
Badria, F.7
-
24
-
-
80052376690
-
Baicalein inhibits the migration and invasive properties of human hepatoma cells
-
Chiu YW, Lin TH, Huang WS, Teng CY, Liou YS, Kuo WH, Lin WL, Huang HI, Tung JN, Huang CY, et al: Baicalein inhibits the migration and invasive properties of human hepatoma cells. Toxicol Appl Pharmacol 255: 316-326, 2011.
-
(2011)
Toxicol Appl Pharmacol
, vol.255
, pp. 316-326
-
-
Chiu, Y.W.1
Lin, T.H.2
Huang, W.S.3
Teng, C.Y.4
Liou, Y.S.5
Kuo, W.H.6
Lin, W.L.7
Huang, H.I.8
Tung, J.N.9
Huang, C.Y.10
-
25
-
-
84856109639
-
A/G polymorphism of the MMP-7 gene promoter region in colorectal cancer
-
Dziki L, Przybyłowska K, Majsterek I, Trzciński R, Mik M and Sygut A: A/G polymorphism of the MMP-7 gene promoter region in colorectal cancer. Pol Przegl Chir 83: 622-626, 2011.
-
(2011)
Pol Przegl Chir
, vol.83
, pp. 622-626
-
-
Dziki, L.1
Przybyłowska, K.2
Majsterek, I.3
Trzciński, R.4
Mik, M.5
Sygut, A.6
-
26
-
-
65249165570
-
ECM degradation assays for analyzing local cell invasion
-
Artym VV, Yamada KM and Mueller SC: ECM degradation assays for analyzing local cell invasion. Methods Mol Biol 522: 211-219, 2009.
-
(2009)
Methods Mol Biol
, vol.522
, pp. 211-219
-
-
Artym, V.V.1
Yamada, K.M.2
Mueller, S.C.3
-
27
-
-
77951266768
-
The role of endogenous reactive oxygen species in oxymatrine-induced caspase-3-dependent apoptosis in human melanoma A375 cells
-
Z hang Y, Liu H, Jin J, Zhu X, Lu L and Jiang H: The role of endogenous reactive oxygen species in oxymatrine-induced caspase-3-dependent apoptosis in human melanoma A375 cells. Anticancer Drugs 21: 494-501, 2010.
-
(2010)
Anticancer Drugs
, vol.21
, pp. 494-501
-
-
Zhang, Y.1
Liu, H.2
Jin, J.3
Zhu, X.4
Lu, L.5
Jiang, H.6
-
28
-
-
33646867673
-
Involvement of MAPK pathway in TNF-Alpha-induced MMP-9 expression in human trophoblastic cells
-
Cohen M, Meisser A, Haenggeli L and Bischof P: Involvement of MAPK pathway in TNF-Alpha-induced MMP-9 expression in human trophoblastic cells. Mol Hum Reprod 12: 225-232, 2006.
-
(2006)
Mol Hum Reprod
, vol.12
, pp. 225-232
-
-
Cohen, M.1
Meisser, A.2
Haenggeli, L.3
Bischof, P.4
-
29
-
-
84874441180
-
Sphingosine kinase 1 enhances colon cancer cell proliferation and invasion by upregulating the production of MMP-2/9 and uPA via MAPK pathways
-
Liu SQ, Huang JA, Qin MB, Su YJ, Lai MY, Jiang HX and Tang G D: Sphingosine kinase 1 enhances colon cancer cell proliferation and invasion by upregulating the production of MMP-2/9 and uPA via MAPK pathways. Int J Colorectal Dis 27: 1569-1578, 2012.
-
(2012)
Int J Colorectal Dis
, vol.27
, pp. 1569-1578
-
-
Liu, S.Q.1
Huang, J.A.2
Qin, M.B.3
Su, Y.J.4
Lai, M.Y.5
Jiang, H.X.6
Tang, G.D.7
-
30
-
-
84863269090
-
Ethanol extracts of fruiting bodies of Antrodia cinnamomea suppress CL1-5 human lung adenocarcinoma cells migration by inhibiting matrix metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt signaling pathways
-
Chen YY, Liu FC, Chou PY, Chien YC, Chang WS, Huang GJ, Wu CH and Sheu MJ: Ethanol extracts of fruiting bodies of Antrodia cinnamomea suppress CL1-5 human lung adenocarcinoma cells migration by inhibiting matrix metalloproteinase-2/9 through ERK, JNK, p38, and PI3K/Akt signaling pathways. Evid Based Complement Alternat Med 2012: 378415, 2012.
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
, pp. 378415
-
-
Chen, Y.Y.1
Liu, F.C.2
Chou, P.Y.3
Chien, Y.C.4
Chang, W.S.5
Huang, G.J.6
Wu, C.H.7
Sheu, M.J.8
-
31
-
-
84931569046
-
CRKL promotes lung cancer cell invasion through ERK-MMP9 pathway
-
Lin F, Chengyao X, Qingchang L, Qianze D, Enhua W and Yan W: CRKL promotes lung cancer cell invasion through ERK-MMP9 pathway. Mol Carcinog 54 (Suppl 1): E35-E44, 2014.
-
(2014)
Mol Carcinog
, vol.54
, pp. E35-E44
-
-
Lin, F.1
Chengyao, X.2
Qingchang, L.3
Qianze, D.4
Enhua, W.5
Yan, W.6
-
32
-
-
84875058087
-
A Chinese herbal formula, Yi-Qi-Fu-Sheng, inhibits migration/invasion of colorectal cancer by down-regulating MMP-2/9 via inhibiting the activation of ERK/MAPK signaling pathways
-
Deng W, Sui H, Wang Q, He N, Duan C, Han L, Li Q, Lu M, and Lv S: A Chinese herbal formula, Yi-Qi-Fu-Sheng, inhibits migration/invasion of colorectal cancer by down-regulating MMP-2/9 via inhibiting the activation of ERK/MAPK signaling pathways. BMC Complement Altern Med 13: 65, 2013.
-
(2013)
BMC Complement Altern Med
, vol.13
, pp. 65
-
-
Deng, W.1
Sui, H.2
Wang, Q.3
He, N.4
Duan, C.5
Han, L.6
Li, Q.7
Lu, M.8
Lv, S.9
-
33
-
-
84862336710
-
Insidious role of nitric oxide in migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of cGMP-PKG-ERK signaling pathways
-
Babykutty S, Suboj P, Srinivas P, Nair AS, Chandramohan K and Gopala S: Insidious role of nitric oxide in migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of cGMP-PKG-ERK signaling pathways. Clin Exp Metastasis 29: 471-492, 2012.
-
(2012)
Clin Exp Metastasis
, vol.29
, pp. 471-492
-
-
Babykutty, S.1
Suboj, P.2
Srinivas, P.3
Nair, A.S.4
Chandramohan, K.5
Gopala, S.6
|