The role of endogenous reactive oxygen species in oxymatrine-induced caspase-3-dependent apoptosis in human melanoma A375 cells

Anti-Cancer Drugs

Volumn 21, Issue 5, 2010, Pages 494-501

  Zhang, Yingfan ^a   Liu, Huanhai ^a   Jin, Jiyang ^b   Zhu, Xiaohai ^a   Lu, Lixuan ^a   Jiang, Hua ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SOUTHEAST UNIVERSITY   (China)

Author keywords

A375 cells; Apoptosis; Melanoma; Oxymatrine; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 9; CYTOCHROME C; GLUTATHIONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OXYMATRINE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL FRACTIONATION; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; HUMAN; HUMAN CELL; MELANOMA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACETYLCYSTEINE; ALKALOIDS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MELANOMA; OXIDATIVE STRESS; QUINOLIZINES; REACTIVE OXYGEN SPECIES;

EID: 77951266768     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/CAD.0b013e328336e927     Document Type: Article

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