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Volumn 14, Issue 3, 2013, Pages 6012-6025

Inhibitory effect of baicalin and baicalein on ovarian cancer cells

Author keywords

Baicalein; Baicalin; Cell viability; HIF 1a; Ovarian cancer; VEGF

Indexed keywords

BAICALEIN; BAICALIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYC PROTEIN; PROTEIN KINASE B; VASCULOTROPIN;

EID: 84875540393     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14036012     Document Type: Article
Times cited : (104)

References (33)
  • 5
    • 80053446135 scopus 로고    scopus 로고
    • Platinum resistance in breast and ovarian cancer cell lines
    • Eckstein, N. Platinum resistance in breast and ovarian cancer cell lines. J. Exp. Clin. Cancer Res. 2011, 30, 91.
    • (2011) J. Exp. Clin. Cancer Res. , vol.30 , pp. 91
    • Eckstein, N.1
  • 7
    • 33947261994 scopus 로고    scopus 로고
    • Diet and cancer prevention: Where we are, where we are going
    • Gonzalez, C.A.; Riboli, E. Diet and cancer prevention: where we are, where we are going. Nutr. Cancer 2006, 56, 225-231.
    • (2006) Nutr. Cancer , vol.56 , pp. 225-231
    • Gonzalez, C.A.1    Riboli, E.2
  • 8
    • 33847797095 scopus 로고    scopus 로고
    • Prospective study of intake of fruit, vegetables, and carotenoids and the risk of adult glioma
    • Holick, C.N.; Giovannucci, E.L.; Rosner, B.; Stampfer, M.J.; Michaud, D.S. Prospective study of intake of fruit, vegetables, and carotenoids and the risk of adult glioma. Am. J. Clin. Nutr. 2007, 85, 877-886.
    • (2007) Am. J. Clin. Nutr. , vol.85 , pp. 877-886
    • Holick, C.N.1    Giovannucci, E.L.2    Rosner, B.3    Stampfer, M.J.4    Michaud, D.S.5
  • 10
    • 4444378842 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma
    • Nishida, N.; Yano, H.; Komai, K.; Nishida, T.; Kamura, T.; Kojiro, M. Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma. Cancer 2004, 101, 1364-1374.
    • (2004) Cancer , vol.101 , pp. 1364-1374
    • Nishida, N.1    Yano, H.2    Komai, K.3    Nishida, T.4    Kamura, T.5    Kojiro, M.6
  • 13
    • 36749022239 scopus 로고    scopus 로고
    • Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT
    • Chao, J.I.; Su, W.C.; Liu, H.F. Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT. Mol. Cancer Ther. 2007, 6, 3039-3048.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 3039-3048
    • Chao, J.I.1    Su, W.C.2    Liu, H.F.3
  • 14
    • 84860641820 scopus 로고    scopus 로고
    • Advances in the treatment of ovarian cancer: A potential role of antiinflammatory phytochemicals
    • Chen, S.S.; Michael, A.; Butler-Manuel, S.A. Advances in the treatment of ovarian cancer: A potential role of antiinflammatory phytochemicals. Discov. Med. 2012, 13, 7-17.
    • (2012) Discov. Med. , vol.13 , pp. 7-17
    • Chen, S.S.1    Michael, A.2    Butler-Manuel, S.A.3
  • 15
    • 70449643130 scopus 로고    scopus 로고
    • Kaempferol inhibits angiogenesis and VEGF expression through both HIF dependent and independent pathways in human ovarian cancer cells
    • Luo, H.; Rankin, G.O.; Liu, L.; Daddysman, M.K.; Jiang, B.H.; Chen, Y.C. Kaempferol inhibits angiogenesis and VEGF expression through both HIF dependent and independent pathways in human ovarian cancer cells. Nutr. Cancer 2009, 61, 554-563.
    • (2009) Nutr. Cancer , vol.61 , pp. 554-563
    • Luo, H.1    Rankin, G.O.2    Liu, L.3    Daddysman, M.K.4    Jiang, B.H.5    Chen, Y.C.6
  • 16
    • 80052263870 scopus 로고    scopus 로고
    • Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway
    • Luo, H.; Rankin, G.O.; Juliano, N.; Jiang, B.H.; Chen, Y.C. Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway. Food Chem. 2012, 130, 321-328.
    • (2012) Food Chem , vol.130 , pp. 321-328
    • Luo, H.1    Rankin, G.O.2    Juliano, N.3    Jiang, B.H.4    Chen, Y.C.5
  • 18
    • 33847688864 scopus 로고    scopus 로고
    • Pro-Apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells
    • Choi, E.J.; Kim, T.; Lee, M.S. Pro-Apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells. Life Sci. 2007, 80, 1403-1408.
    • (2007) Life Sci. , vol.80 , pp. 1403-1408
    • Choi, E.J.1    Kim, T.2    Lee, M.S.3
  • 19
    • 20444432446 scopus 로고    scopus 로고
    • In vitro studies of baicalin alone or in combination with Salvia miltiorrhiza extract as a potential anti-cancer agent
    • Franek, K.J.; Zhou, Z.; Zhang, W.D.; Chen, W.Y. In vitro studies of baicalin alone or in combination with Salvia miltiorrhiza extract as a potential anti-cancer agent. Int. J. Oncol. 2005, 26, 217-224.
    • (2005) Int. J. Oncol. , vol.26 , pp. 217-224
    • Franek, K.J.1    Zhou, Z.2    Zhang, W.D.3    Chen, W.Y.4
  • 20
    • 33749448510 scopus 로고    scopus 로고
    • The Epidemiology of Ovarian Cancer
    • In Bartlett, J.M.S., Ed.; Humana Press: Totowa, NJ, USA
    • Banks, E. The Epidemiology of Ovarian Cancer. In Ovarian Cancer Methods and Protocols; Bartlett, J.M.S., Ed.; Humana Press: Totowa, NJ, USA, 2000; pp. 3-6.
    • (2000) Ovarian Cancer Methods and Protocols , pp. 3-6
    • Banks, E.1
  • 21
    • 4444315616 scopus 로고    scopus 로고
    • Canadian Cancer Registries Epidemiology Research Group. A case-control study of diet and the risk of ovarian cancer
    • Pan, S.Y.; Ugnat, A.M.; Mao, Y.; Wen, S.W.; Johnson, K.C.; Canadian Cancer Registries Epidemiology Research Group. A case-control study of diet and the risk of ovarian cancer. Cancer Epidemiol. Biomarkers Prev. 2004, 13, 1521-1527.
    • (2004) Cancer Epidemiol. Biomarkers Prev , vol.13 , pp. 1521-1527
    • Pan, S.Y.1    Ugnat, A.M.2    Mao, Y.3    Wen, S.W.4    Johnson, K.C.5
  • 22
    • 35348820076 scopus 로고    scopus 로고
    • A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer
    • Gates, M.A.; Tworoger, S.S.; Hecht, J.L.; de Vivo, I.; Rosner, B.; Hankinson, S.E. A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer. Int. J. Cancer 2007, 121, 2225-2232.
    • (2007) Int. J. Cancer , vol.121 , pp. 2225-2232
    • Gates, M.A.1    Tworoger, S.S.2    Hecht, J.L.3    de Vivo, I.4    Rosner, B.5    Hankinson, S.E.6
  • 23
    • 0035212167 scopus 로고    scopus 로고
    • Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest
    • Ikezoe, T.; Chen, S.S.; Heber, D.; Taguchi, H.; Koeffler, H.P. Baicalin is a major component of PC-SPES which inhibits the proliferation of human cancer cells via apoptosis and cell cycle arrest. Prostate 2001, 49, 285-292.
    • (2001) Prostate , vol.49 , pp. 285-292
    • Ikezoe, T.1    Chen, S.S.2    Heber, D.3    Taguchi, H.4    Koeffler, H.P.5
  • 24
    • 58749114381 scopus 로고    scopus 로고
    • New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin
    • Li-Weber, M. New therapeutic aspects of flavones: The anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. Cancer Treat Rev. 2009, 35, 57-68.
    • (2009) Cancer Treat Rev. , vol.35 , pp. 57-68
    • Li-Weber, M.1
  • 25
    • 84866037931 scopus 로고    scopus 로고
    • The different inhibitory effects of Huang-Lian-Jie-Du-Tang on cyclooxygenase 2 and 5-lipoxygenase
    • Li, L.; Zeng, H.; Shan, L.; Yuan, X.; Li, Y.; Liu, R.; Zhang, W. The different inhibitory effects of Huang-Lian-Jie-Du-Tang on cyclooxygenase 2 and 5-lipoxygenase. J. Ethnopharmacol. 2012, 143, 732-739.
    • (2012) J. Ethnopharmacol , vol.143 , pp. 732-739
    • Li, L.1    Zeng, H.2    Shan, L.3    Yuan, X.4    Li, Y.5    Liu, R.6    Zhang, W.7
  • 26
    • 84865431008 scopus 로고    scopus 로고
    • Baicalein induces G1 arrest in oral cancer cells by enhancing the degradation of cyclin D1 and activating AhR to decrease Rb phosphorylation
    • Cheng, Y.H.; Li, L.A.; Lin, P.; Cheng, L.C.; Hung, C.H.; Chang, N.W.; Lin, C. Baicalein induces G1 arrest in oral cancer cells by enhancing the degradation of cyclin D1 and activating AhR to decrease Rb phosphorylation. Toxicol. Appl. Pharmacol. 2012, 263, 360-367.
    • (2012) Toxicol. Appl. Pharmacol , vol.263 , pp. 360-367
    • Cheng, Y.H.1    Li, L.A.2    Lin, P.3    Cheng, L.C.4    Hung, C.H.5    Chang, N.W.6    Lin, C.7
  • 27
    • 79960666903 scopus 로고    scopus 로고
    • Baicalein potently suppresses angiogenesis induced by vascular endothelial growth factor through the p53/Rb signaling pathway leading to G1/S cell cycle arrest
    • Ling, Y.; Chen, Y.; Chen, P.; Hui, H.; Song, X.; Lu, Z.; Li, C.; Lu, N.; Guo, Q. Baicalein potently suppresses angiogenesis induced by vascular endothelial growth factor through the p53/Rb signaling pathway leading to G1/S cell cycle arrest. Exp. Biol. Med. (Maywood) 2011, 236, 851-858.
    • (2011) Exp. Biol. Med. (Maywood) , vol.236 , pp. 851-858
    • Ling, Y.1    Chen, Y.2    Chen, P.3    Hui, H.4    Song, X.5    Lu, Z.6    Li, C.7    Lu, N.8    Guo, Q.9
  • 28
    • 78751545034 scopus 로고    scopus 로고
    • Baicalin increases VEGF expression and angiogenesis by activating the ERRα/PGC-1α pathway
    • Zhang, K.; Lu, J.; Mori, T.; Smith-Powell, L.; Synold, T.W.; Chen, S.; Wen, W. Baicalin increases VEGF expression and angiogenesis by activating the ERRα/PGC-1α pathway. Cardiovasc. Res. 2011, 89, 426-435.
    • (2011) Cardiovasc. Res. , vol.89 , pp. 426-435
    • Zhang, K.1    Lu, J.2    Mori, T.3    Smith-Powell, L.4    Synold, T.W.5    Chen, S.6    Wen, W.7
  • 29
    • 52049112539 scopus 로고    scopus 로고
    • Baicalein suppresses hypoxia-induced HIF-1alpha protein accumulation and activation through inhibition of reactive oxygen species and PI 3-kinase/Akt pathway in BV2 murine microglial cells
    • Hwang, K.Y.; Oh, Y.T.; Yoon, H.; Lee, J.; Kim, H.; Choe, W.; Kang, I. Baicalein suppresses hypoxia-induced HIF-1alpha protein accumulation and activation through inhibition of reactive oxygen species and PI 3-kinase/Akt pathway in BV2 murine microglial cells. Neurosci. Lett. 2008, 444, 264-269.
    • (2008) Neurosci. Lett. , vol.444 , pp. 264-269
    • Hwang, K.Y.1    Oh, Y.T.2    Yoon, H.3    Lee, J.4    Kim, H.5    Choe, W.6    Kang, I.7
  • 30
    • 80052545224 scopus 로고    scopus 로고
    • Effects of baicalin on proliferation and apoptosis of adriamycin-resistant human leukemia HL-60/ADR cells
    • Zheng, J.; Hu, J.D.; Huang, Y.; Chen, B.Y. Effects of baicalin on proliferation and apoptosis of adriamycin-resistant human leukemia HL-60/ADR cells. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2009, 17, 1198-1202.
    • (2009) Zhongguo Shi Yan Xue Ye Xue Za Zhi , vol.17 , pp. 1198-1202
    • Zheng, J.1    Hu, J.D.2    Huang, Y.3    Chen, B.Y.4
  • 31
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-jB: The enemy within
    • Aggarwal, B.B. Nuclear factor-jB: The enemy within. Cancer Cell 2004, 6, 203-206.
    • (2004) Cancer Cell , vol.6 , pp. 203-206
    • Aggarwal, B.B.1
  • 32
    • 43049128529 scopus 로고    scopus 로고
    • Tenets of PTEN tumor suppression
    • Salmena, L.; Carracedo, A.; Pandolfi, P.P. Tenets of PTEN tumor suppression. Cell 2008, 133, 403-414.
    • (2008) Cell , vol.133 , pp. 403-414
    • Salmena, L.1    Carracedo, A.2    Pandolfi, P.P.3
  • 33
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama, T.; Dixon, J.E. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 1998, 273, 13375-13378.
    • (1998) J. Biol. Chem , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.