Age-dependent shift in macrophage polarisation causes inflammation-mediated degeneration of enteric nervous system

Gut

Volumn 67, Issue 5, 2018, Pages 827-836

  Becker, Laren ^a   Nguyen, Linh ^a   Gill, Jaspreet ^a   Kulkarni, Subhash ^b   Pasricha, Pankaj Jay ^b   Habtezion, Aida ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AGEING; ENTERIC NERVOUS SYSTEM; INFLAMMATION; MACROPHAGES

Indexed keywords

CYTOKINE; INTERLEUKIN 6; TRANSCRIPTION FACTOR FKHRL1; TUMOR NECROSIS FACTOR; FOXO3 PROTEIN, MOUSE;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL ISOLATION; CONTROLLED STUDY; IMMUNOCOMPETENT CELL; INFANT; INFLAMMATION; INTESTINE INNERVATION; LONGEVITY; LONGITUDINAL MUSCLE-MYENTERIC PLEXUS PREPARATION; MACROPHAGE; MALE; MOUSE; NERVE DEGENERATION; NEURAL STEM CELL; NONHUMAN; PATHOGENESIS; POLARIZATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMALL INTESTINE; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; METABOLISM; PATHOLOGY; PHENOTYPE; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AGING; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; CYTOKINES; ENTERIC NERVOUS SYSTEM; FLOW CYTOMETRY; FORKHEAD BOX PROTEIN O3; GENE EXPRESSION REGULATION; INFLAMMATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; PHENOTYPE; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 85016277463     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2016-312940     Document Type: Article

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