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Volumn 49, Issue 5, 2017, Pages 789-794

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

(86)  Melin, Beatrice S a   Barnholtz Sloan, Jill S b   Wrensch, Margaret R c,d   Johansen, Christoffer e,ah   Il'yasova, Dora f,g   Kinnersley, Ben h   Ostrom, Quinn T b   Labreche, Karim h,i   Chen, Yanwen b   Armstrong, Georgina j   Liu, Yanhong j   Eckel Passow, Jeanette E k   Decker, Paul A k   Labussière, Marianne i   Idbaih, Ahmed i,l   Hoang Xuan, Khe i,l   Di Stefano, Anna Luisa i,l   Mokhtari, Karima i,l   Delattre, Jean Yves i,l   Broderick, Peter h   more..


Author keywords

[No Author keywords available]

Indexed keywords

ISOCITRATE DEHYDROGENASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN MDMX;

EID: 85016134775     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3823     Document Type: Article
Times cited : (236)

References (76)
  • 1
    • 53949091844 scopus 로고    scopus 로고
    • Brain tumor epidemiology: Consensus from the brain tumor epidemiology consortium
    • Bondy, M.L. et al. Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer 113, 1953-1968 (2008).
    • (2008) Cancer , vol.113 , pp. 1953-1968
    • Bondy, M.L.1
  • 2
    • 85020249099 scopus 로고    scopus 로고
    • CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2008-2012
    • Ostrom, Q.T. et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012. Neuro-oncol. 17 (Suppl. 4), iv1-iv62 (2015).
    • (2015) Neuro-oncol. , vol.17 , pp. iv1-iv62
    • Ostrom, Q.T.1
  • 3
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumors of the central nervous system
    • Louis, D.N. et al. The 2007 WHO classification of tumors of the central nervous system. Acta Neuropathol. 114, 97-109 (2007).
    • (2007) Acta Neuropathol. , vol.114 , pp. 97-109
    • Louis, D.N.1
  • 4
    • 84929620816 scopus 로고    scopus 로고
    • CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2007-2011
    • Ostrom, Q.T. et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro-oncol. 16, iv1-iv63 (2014).
    • (2014) Neuro-oncol. , vol.16 , pp. iv1-iv63
    • Ostrom, Q.T.1
  • 5
    • 84902489371 scopus 로고    scopus 로고
    • The epidemiology of glioma in adults: A 'state of the science' review
    • Ostrom, Q.T. et al. The epidemiology of glioma in adults: a 'state of the science' review. Neuro-oncol. 16, 896-913 (2014).
    • (2014) Neuro-oncol. , vol.16 , pp. 896-913
    • Ostrom, Q.T.1
  • 6
    • 65349119958 scopus 로고    scopus 로고
    • Familial risks in nervous-system tumors: A histology-specific analysis from Sweden and Norway
    • Hemminki, K., Tretli, S., Sundquist, J., Johannesen, T.B. & Granstrom, C. Familial risks in nervous-system tumors: a histology-specific analysis from Sweden and Norway. Lancet Oncol. 10, 481-488 (2009).
    • (2009) Lancet Oncol. , vol.10 , pp. 481-488
    • Hemminki, K.1    Tretli, S.2    Sundquist, J.3    Johannesen, T.B.4    Granstrom, C.5
  • 7
    • 79959793196 scopus 로고    scopus 로고
    • Chromosome 7p11.2 (EGFR) variation influences glioma risk
    • Sanson, M. et al. Chromosome 7p11.2 (EGFR) variation influences glioma risk. Hum. Mol. Genet. 20, 2897-2904 (2011).
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 2897-2904
    • Sanson, M.1
  • 8
    • 68149180890 scopus 로고    scopus 로고
    • Genome-wide association study identifies five susceptibility loci for glioma
    • Shete, S. et al. Genome-wide association study identifies five susceptibility loci for glioma. Nat. Genet. 41, 899-904 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 899-904
    • Shete, S.1
  • 9
    • 68149180891 scopus 로고    scopus 로고
    • Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility
    • Wrensch, M. et al. Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility. Nat. Genet. 41, 905-908 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 905-908
    • Wrensch, M.1
  • 10
    • 84943145966 scopus 로고    scopus 로고
    • Genome-wide association study identifies multiple susceptibility loci for glioma
    • Kinnersley, B. et al. Genome-wide association study identifies multiple susceptibility loci for glioma. Nat. Commun. 6, 8559 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 8559
    • Kinnersley, B.1
  • 11
    • 84904101984 scopus 로고    scopus 로고
    • Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk
    • Walsh, K.M. et al. Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. Nat. Genet. 46, 731-735 (2014).
    • (2014) Nat. Genet. , vol.46 , pp. 731-735
    • Walsh, K.M.1
  • 12
    • 84866932650 scopus 로고    scopus 로고
    • A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation
    • Jenkins, R.B. et al. A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. Nat. Genet. 44, 1122-1125 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 1122-1125
    • Jenkins, R.B.1
  • 13
    • 84870988159 scopus 로고    scopus 로고
    • Genome-wide association study of glioma and meta-analysis
    • Rajaraman, P. et al. Genome-wide association study of glioma and meta-analysis. Hum. Genet. 131, 1877-1888 (2012).
    • (2012) Hum. Genet. , vol.131 , pp. 1877-1888
    • Rajaraman, P.1
  • 14
    • 80055009292 scopus 로고    scopus 로고
    • A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
    • Stacey, S.N. et al. A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat. Genet. 43, 1098-1103 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 1098-1103
    • Stacey, S.N.1
  • 15
    • 84949009442 scopus 로고    scopus 로고
    • Quantifying the heritability of glioma using genome-wide complex trait analysis
    • Kinnersley, B. et al. Quantifying the heritability of glioma using genome-wide complex trait analysis. Sci. Rep. 5, 17267 (2015).
    • (2015) Sci. Rep. , vol.5 , pp. 17267
    • Kinnersley, B.1
  • 16
    • 84878682420 scopus 로고    scopus 로고
    • The genotype-tissue expression (GTEx) project
    • Lonsdale, J. et al. The Genotype-Tissue Expression (GTEx) project. Nat. Genet. 45, 580-585 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 580-585
    • Lonsdale, J.1
  • 17
    • 84885018609 scopus 로고    scopus 로고
    • Systematic identification of trans eQTLs as putative drivers of known disease associations
    • Westra, H.J. et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat. Genet. 45, 1238-1243 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 1238-1243
    • Westra, H.J.1
  • 18
    • 84961927084 scopus 로고    scopus 로고
    • Integration of summary data from GWAS and eQTL studies predicts complex-trait gene targets
    • Zhu, Z. et al. Integration of summary data from GWAS and eQTL studies predicts complex-trait gene targets. Nat. Genet. 48, 481-487 (2016).
    • (2016) Nat. Genet. , vol.48 , pp. 481-487
    • Zhu, Z.1
  • 19
    • 84897459814 scopus 로고    scopus 로고
    • An atlas of active enhancers across human cell types and tissues
    • Andersson, R. et al. An atlas of active enhancers across human cell types and tissues. Nature 507, 455-461 (2014).
    • (2014) Nature , vol.507 , pp. 455-461
    • Andersson, R.1
  • 20
    • 84888015137 scopus 로고    scopus 로고
    • Super-enhancers in the control of cell identity and disease
    • Hnisz, D. et al. Super-enhancers in the control of cell identity and disease. Cell 155, 934-947 (2013).
    • (2013) Cell , vol.155 , pp. 934-947
    • Hnisz, D.1
  • 21
    • 84878721081 scopus 로고    scopus 로고
    • Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14
    • Ruark, E. et al. Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. Nat. Genet. 45, 686-689 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 686-689
    • Ruark, E.1
  • 22
    • 84866919001 scopus 로고    scopus 로고
    • Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions
    • Wu, C. et al. Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. Nat. Genet. 44, 1090-1097 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 1090-1097
    • Wu, C.1
  • 23
    • 0343819885 scopus 로고    scopus 로고
    • Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification
    • Riemenschneider, M.J. et al. Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification. Cancer Res. 59, 6091-6096 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 6091-6096
    • Riemenschneider, M.J.1
  • 24
    • 34547786100 scopus 로고    scopus 로고
    • Mapping of deletion and translocation breakpoints in 1q44 implicates the serine-threonine kinase AKT3 in postnatal microcephaly and agenesis of the corpus callosum
    • Boland, E. et al. Mapping of deletion and translocation breakpoints in 1q44 implicates the serine-threonine kinase AKT3 in postnatal microcephaly and agenesis of the corpus callosum. Am. J. Hum. Genet. 81, 292-303 (2007).
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 292-303
    • Boland, E.1
  • 25
    • 84925242229 scopus 로고    scopus 로고
    • Genomically amplified akt3 activates DNA repair pathway and promotes glioma progression
    • Turner, K.M. et al. Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression. Proc. Natl. Acad. Sci. USA 112, 3421-3426 (2015).
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. 3421-3426
    • Turner, K.M.1
  • 26
    • 20844462896 scopus 로고    scopus 로고
    • LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
    • Gur, G. et al. LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation. EMBO J. 23, 3270-3281 (2004).
    • (2004) EMBO J. , vol.23 , pp. 3270-3281
    • Gur, G.1
  • 27
    • 84935472423 scopus 로고    scopus 로고
    • LRIG1 enhances the radio-sensitivity of radio-resistant human glioblastoma U251 cells via attenuation of the EGFR-AKT signaling pathway
    • Yang, J.A. et al. LRIG1 enhances the radio-sensitivity of radio-resistant human glioblastoma U251 cells via attenuation of the EGFR-AKT signaling pathway. Int. J. Clin. Exp. Pathol. 8, 3580-3590 (2015).
    • (2015) Int. J. Clin. Exp. Pathol. , vol.8 , pp. 3580-3590
    • Yang, J.A.1
  • 28
    • 84928951116 scopus 로고    scopus 로고
    • MiR-20a mediates temozolomide resistance in glioblastoma cells via negatively regulating LRIG1 expression
    • Wei, J. et al. miR-20a mediates temozolomide resistance in glioblastoma cells via negatively regulating LRIG1 expression. Biomed. Pharmacother. 71, 112-118 (2015).
    • (2015) Biomed. Pharmacother. , vol.71 , pp. 112-118
    • Wei, J.1
  • 29
    • 65349150503 scopus 로고    scopus 로고
    • IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
    • Watanabe, T., Nobusawa, S., Kleihues, P. & Ohgaki, H. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am. J. Pathol. 174, 1149-1153 (2009).
    • (2009) Am. J. Pathol. , vol.174 , pp. 1149-1153
    • Watanabe, T.1    Nobusawa, S.2    Kleihues, P.3    Ohgaki, H.4
  • 30
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • Yan, H. et al. IDH1 and IDH2 mutations in gliomas. N. Engl. J. Med. 360, 765-773 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 765-773
    • Yan, H.1
  • 31
    • 77952108366 scopus 로고    scopus 로고
    • Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
    • Noushmehr, H. et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17, 510-522 (2010).
    • (2010) Cancer Cell , vol.17 , pp. 510-522
    • Noushmehr, H.1
  • 32
    • 79251470741 scopus 로고    scopus 로고
    • DNA methylation, isocitrate dehydrogenase mutation and survival in glioma
    • Christensen, B.C. et al. DNA methylation, isocitrate dehydrogenase mutation and survival in glioma. J. Natl. Cancer Inst. 103, 143-153 (2011).
    • (2011) J. Natl. Cancer Inst. , vol.103 , pp. 143-153
    • Christensen, B.C.1
  • 33
    • 70249097408 scopus 로고    scopus 로고
    • Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
    • Sanson, M. et al. Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J. Clin. Oncol. 27, 4150-4154 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 4150-4154
    • Sanson, M.1
  • 34
    • 84932649039 scopus 로고    scopus 로고
    • Glioma groups based on 1p/19q, IDH and TERT promoter mutations in tumors
    • Eckel-Passow, J.E. et al. Glioma groups based on 1p/19q, IDH and TERT promoter mutations in tumors. N. Engl. J. Med. 372, 2499-2508 (2015).
    • (2015) N. Engl. J. Med. , vol.372 , pp. 2499-2508
    • Eckel-Passow, J.E.1
  • 35
    • 84946553989 scopus 로고    scopus 로고
    • Telomere maintenance and the etiology of adult glioma
    • Walsh, K.M. et al. Telomere maintenance and the etiology of adult glioma. Neuro-oncol. 17, 1445-1452 (2015).
    • (2015) Neuro-oncol. , vol.17 , pp. 1445-1452
    • Walsh, K.M.1
  • 36
    • 70350031814 scopus 로고    scopus 로고
    • RPA-like mammalian ctc1-stn1-ten1 complex binds to single-stranded DNA and protects telomeres independently of the pot1 pathway
    • Miyake, Y. et al. RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. Mol. Cell 36, 193-206 (2009).
    • (2009) Mol. Cell , vol.36 , pp. 193-206
    • Miyake, Y.1
  • 37
    • 84865263603 scopus 로고    scopus 로고
    • The human CST complex is a terminator of telomerase activity
    • Chen, L.Y., Redon, S. & Lingner, J. The human CST complex is a terminator of telomerase activity. Nature 488, 540-544 (2012).
    • (2012) Nature , vol.488 , pp. 540-544
    • Chen, L.Y.1    Redon, S.2    Lingner, J.3
  • 38
    • 84930462553 scopus 로고    scopus 로고
    • Germline mutations in shelterin complex genes are associated with familial glioma
    • Bainbridge, M.N. et al. Germline mutations in shelterin complex genes are associated with familial glioma. J. Natl. Cancer Inst. 107, 384 (2014).
    • (2014) J. Natl. Cancer Inst. , vol.107 , pp. 384
    • Bainbridge, M.N.1
  • 39
    • 84940656427 scopus 로고    scopus 로고
    • Genetic determinants of telomere length and risk of common cancers: A mendelian randomization study
    • Zhang, C. et al. Genetic determinants of telomere length and risk of common cancers: a mendelian randomization study. Hum. Mol. Genet. 24, 5356-5366 (2015).
    • (2015) Hum. Mol. Genet. , vol.24 , pp. 5356-5366
    • Zhang, C.1
  • 40
    • 84952332384 scopus 로고    scopus 로고
    • Longer genotypically estimated leukocyte telomere length is associated with increased adult glioma risk
    • Walsh, K.M. et al. Longer genotypically estimated leukocyte telomere length is associated with increased adult glioma risk. Oncotarget 6, 42468-42477 (2015).
    • (2015) Oncotarget , vol.6 , pp. 42468-42477
    • Walsh, K.M.1
  • 41
    • 84955561447 scopus 로고    scopus 로고
    • Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma
    • Ceccarelli, M. et al. Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma. Cell 164, 550-563 (2016).
    • (2016) Cell , vol.164 , pp. 550-563
    • Ceccarelli, M.1
  • 42
    • 84982124664 scopus 로고    scopus 로고
    • Endoplasmic-reticulum-stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG and rad51
    • Xipell, E. et al. Endoplasmic-reticulum-stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG and Rad51. Neuro-oncol. 18, 1109-1119 (2016).
    • (2016) Neuro-oncol. , vol.18 , pp. 1109-1119
    • Xipell, E.1
  • 43
    • 84904122104 scopus 로고    scopus 로고
    • The role of JAK-STAT signaling within the CNS
    • Nicolas, C.S. et al. The role of JAK-STAT signaling within the CNS. JAK-STAT 2, e22925 (2013).
    • (2013) JAK-STAT , vol.2 , pp. e22925
    • Nicolas, C.S.1
  • 44
    • 84932628860 scopus 로고    scopus 로고
    • Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
    • Cancer Genome Atlas Research Network. Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N. Engl. J. Med. 372, 2481-2498 (2015).
    • (2015) N. Engl. J. Med. , vol.372 , pp. 2481-2498
  • 45
    • 33645982290 scopus 로고    scopus 로고
    • Mobile phone use and risk of glioma in adults: Case-control study
    • Hepworth, S.J. et al. Mobile phone use and risk of glioma in adults: case-control study. BMJ 332, 883-887 (2006).
    • (2006) BMJ , vol.332 , pp. 883-887
    • Hepworth, S.J.1
  • 46
    • 84960080630 scopus 로고    scopus 로고
    • The glioma international case-control study: A report from the genetic epidemiology of glioma international consortium
    • Amirian, E.S. et al. The Glioma International Case-Control Study: a report from the Genetic Epidemiology of Glioma International Consortium. Am. J. Epidemiol. 183, 85-91 (2016).
    • (2016) Am. J. Epidemiol. , vol.183 , pp. 85-91
    • Amirian, E.S.1
  • 47
    • 84960396158 scopus 로고    scopus 로고
    • FastPop: A rapid principal component-derived method to infer intercontinental ancestry using genetic data
    • Li, Y. et al. FastPop: a rapid principal component-derived method to infer intercontinental ancestry using genetic data. BMC Bioinformatics 17, 122 (2016).
    • (2016) BMC Bioinformatics , vol.17 , pp. 122
    • Li, Y.1
  • 48
    • 34548626804 scopus 로고    scopus 로고
    • The INTERPHONE study: Design, epidemiological methods and description of the study population
    • Cardis, E. et al. The INTERPHONE study: design, epidemiological methods and description of the study population. Eur. J. Epidemiol. 22, 647-664 (2007).
    • (2007) Eur. J. Epidemiol. , vol.22 , pp. 647-664
    • Cardis, E.1
  • 49
    • 1842574410 scopus 로고    scopus 로고
    • The SU.VI.MAX study: A randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals
    • Hercberg, S. et al. The SU.VI.MAX study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals. Arch. Intern. Med. 164, 2335-2342 (2004).
    • (2004) Arch. Intern. Med. , vol.164 , pp. 2335-2342
    • Hercberg, S.1
  • 50
    • 23844472247 scopus 로고    scopus 로고
    • KORA-gen-resource for population genetics, controls and a broad spectrum of disease phenotypes
    • Wichmann, H.E., Gieger, C., Illig, T. & MONICA-KORA Study Group. KORA-gen-resource for population genetics, controls and a broad spectrum of disease phenotypes. Gesundheitswesen 67 (Suppl. 1), S26-S30 (2005).
    • (2005) Gesundheitswesen , vol.67 , pp. S26-S30
    • Wichmann, H.E.1    Gieger, C.2    Illig, T.3
  • 51
    • 33344470090 scopus 로고    scopus 로고
    • PopGen: Population-based recruitment of patients and controls for the analysis of complex genotype-phenotype relationships
    • Krawczak, M. et al. PopGen: population-based recruitment of patients and controls for the analysis of complex genotype-phenotype relationships. Community Genet. 9, 55-61 (2006).
    • (2006) Community Genet. , vol.9 , pp. 55-61
    • Krawczak, M.1
  • 52
    • 0036342675 scopus 로고    scopus 로고
    • Assessment of clinically silent atherosclerotic disease, and established and novel risk factors for predicting myocardial infarction and cardiac death in healthy middle-aged subjects: Rationale and design of the heinz nixdorf RECALL study. Risk factors, evaluation of coronary calcium and lifestyle
    • Schmermund, A. et al. Assessment of clinically silent atherosclerotic disease, and established and novel risk factors for predicting myocardial infarction and cardiac death in healthy middle-aged subjects: rationale and design of the Heinz Nixdorf RECALL study. Risk factors, evaluation of coronary calcium and lifestyle. Am. Heart J. 144, 212-218 (2002).
    • (2002) Am. Heart J. , vol.144 , pp. 212-218
    • Schmermund, A.1
  • 53
    • 34250001297 scopus 로고    scopus 로고
    • A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
    • Hunter, D.J. et al. A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat. Genet. 39, 870-874 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 870-874
    • Hunter, D.J.1
  • 54
    • 34247548755 scopus 로고    scopus 로고
    • Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
    • Yeager, M. et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat. Genet. 39, 645-649 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 645-649
    • Yeager, M.1
  • 55
    • 0036533677 scopus 로고    scopus 로고
    • History of allergies among adults with glioma and controls
    • Wiemels, J.L. et al. History of allergies among adults with glioma and controls. Int. J. Cancer 98, 609-615 (2002).
    • (2002) Int. J. Cancer , vol.98 , pp. 609-615
    • Wiemels, J.L.1
  • 56
    • 58249122204 scopus 로고    scopus 로고
    • Reproductive factors and hormone use, and risk of adult gliomas
    • Felini, M.J. et al. Reproductive factors and hormone use, and risk of adult gliomas. Cancer Causes Control 20, 87-96 (2009).
    • (2009) Cancer Causes Control , vol.20 , pp. 87-96
    • Felini, M.J.1
  • 57
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie, B.N., Donnelly, P. & Marchini, J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5, e1000529 (2009).
    • (2009) PLoS Genet. , vol.5 , pp. e1000529
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 58
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • 1000 Genomes Project Consortium. A map of human genome variation from population-scale sequencing. Nature 467, 1061-1073 (2010).
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 59
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • Marchini, J., Howie, B., Myers, S., McVean, G. & Donnelly, P. A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet. 39, 906-913 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5
  • 60
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007).
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 559-575
    • Purcell, S.1
  • 61
    • 33846006923 scopus 로고    scopus 로고
    • Population structure and eigenanalysis
    • Patterson, N., Price, A.L. & Reich, D. Population structure and eigenanalysis. PLoS Genet. 2, e190 (2006).
    • (2006) PLoS Genet. , vol.2 , pp. e190
    • Patterson, N.1    Price, A.L.2    Reich, D.3
  • 62
    • 79955664968 scopus 로고    scopus 로고
    • Distinct germline polymorphisms underlie glioma morphologic heterogeneity
    • Jenkins, R.B. et al. Distinct germline polymorphisms underlie glioma morphologic heterogeneity. Cancer Genet. 204, 13-18 (2011).
    • (2011) Cancer Genet. , vol.204 , pp. 13-18
    • Jenkins, R.B.1
  • 63
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard, J.K., Stephens, M. & Donnelly, P. Inference of population structure using multilocus genotype data. Genetics 155, 945-959 (2000).
    • (2000) Genetics , vol.155 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 64
    • 77951751034 scopus 로고    scopus 로고
    • Meta-analysis and imputation refines the association of 15q25 with smoking quantity
    • Liu, J.Z. et al. Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat. Genet. 42, 436-440 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 436-440
    • Liu, J.Z.1
  • 67
    • 84862832570 scopus 로고    scopus 로고
    • Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
    • Yang, J. et al. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat. Genet. 44, 369-375 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 369-375
    • Yang, J.1
  • 68
    • 84858779229 scopus 로고    scopus 로고
    • HaploReg: A resource for exploring chromatin states, conservation and regulatory motif alterations within sets of genetically linked variants
    • Ward, L.D. & Kellis, M. HaploReg: a resource for exploring chromatin states, conservation and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res. 40, D930-D934 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , pp. D930-D934
    • Ward, L.D.1    Kellis, M.2
  • 69
    • 84865712382 scopus 로고    scopus 로고
    • Annotation of functional variation in personal genomes using RegulomeDB
    • Boyle, A.P. et al. Annotation of functional variation in personal genomes using RegulomeDB. Genome Res. 22, 1790-1797 (2012).
    • (2012) Genome Res. , vol.22 , pp. 1790-1797
    • Boyle, A.P.1
  • 70
    • 70249111091 scopus 로고    scopus 로고
    • Targeted capture and massively parallel sequencing of 12 human exomes
    • Ng, S.B. et al. Targeted capture and massively parallel sequencing of 12 human exomes. Nature 461, 272-276 (2009).
    • (2009) Nature , vol.461 , pp. 272-276
    • Ng, S.B.1
  • 71
    • 84923362619 scopus 로고    scopus 로고
    • Integrative analysis of 111 reference human epigenomes
    • Roadmap Epigenomics Consortium. Integrative analysis of 111 reference human epigenomes. Nature 518, 317-330 (2015).
    • (2015) Nature , vol.518 , pp. 317-330
  • 72
    • 45949085378 scopus 로고    scopus 로고
    • Polygenes, risk prediction and targeted prevention of breast cancer
    • Pharoah, P.D., Antoniou, A.C., Easton, D.F. & Ponder, B.A. Polygenes, risk prediction and targeted prevention of breast cancer. N. Engl. J. Med. 358, 2796-2803 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 2796-2803
    • Pharoah, P.D.1    Antoniou, A.C.2    Easton, D.F.3    Ponder, B.A.4
  • 73
    • 78149314589 scopus 로고    scopus 로고
    • Familial aggregation of glioma: A pooled analysis
    • Scheurer, M.E. et al. Familial aggregation of glioma: a pooled analysis. Am. J. Epidemiol. 172, 1099-1107 (2010).
    • (2010) Am. J. Epidemiol. , vol.172 , pp. 1099-1107
    • Scheurer, M.E.1
  • 74
    • 79960405019 scopus 로고    scopus 로고
    • The variant call format and VCFtools
    • Danecek, P. et al. The variant call format and VCFtools. Bioinformatics 27, 2156-2158 (2011).
    • (2011) Bioinformatics , vol.27 , pp. 2156-2158
    • Danecek, P.1
  • 75
    • 84923324232 scopus 로고    scopus 로고
    • VisPIG-A web tool for producing multiregion, multitrack, multiscale plots of genetic data
    • Scales, M., Jager, R., Migliorini, G., Houlston, R.S. & Henrion, M.Y. visPIG-a web tool for producing multiregion, multitrack, multiscale plots of genetic data. PLoS One 9, e107497 (2014).
    • (2014) PLoS One , vol.9 , pp. e107497
    • Scales, M.1    Jager, R.2    Migliorini, G.3    Houlston, R.S.4    Henrion, M.Y.5
  • 76
    • 18444369013 scopus 로고    scopus 로고
    • The structure of haplotype blocks in the human genome
    • Gabriel, S.B. et al. The structure of haplotype blocks in the human genome. Science 296, 2225-2229 (2002).
    • (2002) Science , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1


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