A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis

Genome Medicine

Volumn 9, Issue 1, 2017, Pages

  Taroni, Jaclyn N ^a   Greene, Casey S ^b   Martyanov, Viktor ^a   Wood, Tammara A ^a   Christmann, Romy B ^c   Farber, Harrison W ^c   Lafyatis, Robert A ^c,d   Denton, Christopher P ^e   Hinchcliff, Monique E ^f   Pioli, Patricia A ^a   Mahoney, J Matthew ^g   Whitfield, Michael L ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f NORTHWESTERN UNIVERSITY   (United States)

^g UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Functional genomics; Lung disease; Macrophage; Scleroderma; Systemic sclerosis

Indexed keywords

CATHEPSIN B; CATHEPSIN L; CYSTEINE RICH PROTEIN 61; HERMES ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA INDUCED PROTEIN 3; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ARTICLE; CLUSTER ANALYSIS; COHORT ANALYSIS; CONTROLLED STUDY; ESOPHAGUS TISSUE; FUNCTIONAL GENOMICS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; HUMAN; HUMAN CELL; HUMAN TISSUE; LONGITUDINAL STUDY; LUNG PARENCHYMA; MACROPHAGE ACTIVATION; MAJOR CLINICAL STUDY; MICROENVIRONMENT; PERIPHERAL BLOOD MONONUCLEAR CELL; PULMONARY HYPERTENSION; SKIN BIOPSY; SKIN FIBROSIS; SYSTEMIC SCLEROSIS; TISSUE SPECIFICITY; TRANSCRIPTION INITIATION; UPREGULATION; ANTIBODY SPECIFICITY; BIOPSY; ESOPHAGUS; FIBROSIS; GENETICS; LUNG; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; SKIN;

BIOPSY; ESOPHAGUS; FIBROSIS; GENE REGULATORY NETWORKS; HUMANS; LEUKOCYTES, MONONUCLEAR; LUNG; ORGAN SPECIFICITY; SCLERODERMA, SYSTEMIC; SKIN; TRANSCRIPTOME;

EID: 85016101947     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/s13073-017-0417-1     Document Type: Article

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