Establishing a novel biosynthetic pathway for the production of 3,4-dihydroxybutyric acid from xylose in Escherichia coli

Metabolic Engineering

Volumn 41, Issue , 2017, Pages 39-45

  Wang, Jia ^a   Shen, Xiaolin ^a   Jain, Rachit ^b   Wang, Jian ^b   Yuan, Qipeng ^a   Yan, Yajun ^b  

^a BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^b University of Georgia   (United States)

Author keywords

3; 3 hydroxy butyrolactone; 4 dihydroxybutyric acid; Escherichia coli; Metabolic engineering; Xylose metabolism

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; ESCHERICHIA COLI; METABOLISM; PHYSIOLOGY; XYLOSE;

BIO-MANUFACTURING; BIOSYNTHETIC PATHWAY; BROAD APPLICATION; BUILDING BLOCKES; BUTYROLACTONES; CHEMICAL ROUTES; PHARMACEUTICAL INDUSTRY; PROCESSING CONDITION;

METABOLIC ENGINEERING;

3 HYDROXY GAMMA BUTYROLACTONE; 3,4 DIHYDROXYBUTYRIC ACID; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; BUTYROLACTONE; DEXTRO 3,4-DIHYDROXYBUTANAL DEHYDROGENASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG; XYLOSE; 3,4-DIHYDROXYBUTANOIC ACID; 3-HYDROXY-GAMMA-BUTYROLACTONE; GAMMA BUTYROLACTONE; HYDROXYBUTYRIC ACID;

ARTICLE; BACTERIAL STRAIN; BIOSYNTHESIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ESCHERICHIA COLI; GENETIC MANIPULATION; IN VITRO STUDY; METABOLIC ENGINEERING; METABOLISM; METABOLITE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SCALE UP; ANALOGS AND DERIVATIVES; GENETICS; PROCEDURES;

4-BUTYROLACTONE; ESCHERICHIA COLI; HYDROXYBUTYRATES; METABOLIC ENGINEERING; XYLOSE;

EID: 85015997017     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2017.03.003     Document Type: Article

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