Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions

Nature Methods

Volumn 14, Issue 6, 2017, Pages 573-576

  Shen, John Paul ^a,b,c   Zhao, Dongxin ^c,d   Sasik, Roman ^e   Luebeck, Jens ^e   Birmingham, Amanda ^e   Bojorquez Gomez, Ana ^a   Licon, Katherine ^a   Klepper, Kristin ^a   Pekin, Daniel ^a   Beckett, Alex N ^a   Sanchez, Kyle Salinas ^a   Thomas, Alex ^e   Kuo, Chih Chung ^d,e   Du, Dan ^c,f   Roguev, Assen ^c,g   Lewis, Nathan E ^e,h   Chang, Aaron N ^e   Kreisberg, Jason F ^a,c   Krogan, Nevan ^c,g   Qi, Lei ^c,i   Ideker, Trey ^a,b,c,e   Mali, Prashant ^b,c,d   more..

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c Cancer Cell Map Initiative (CCMI)   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

ⁱ Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUIDE RNA; TUMOR PROTEIN;

ARTICLE; CANCER CELL LINE; CELL POPULATION; COMBINATORIAL LIBRARY; CONTROLLED STUDY; CRISPR CAS SYSTEM; CRISPR CAS9 SYSTEM; GENE INACTIVATION; GENE INTERACTION; GENE MAPPING; GENETIC SCREENING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TUMOR GENE; TUMOR SUPPRESSOR GENE; A-549 CELL LINE; CHROMOSOMAL MAPPING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; COMBINATORIAL CHEMISTRY; EPISTASIS; GENETICS; HELA CELL LINE; HIGH THROUGHPUT SEQUENCING; PROCEDURES; TUMOR CELL LINE;

A549 CELLS; CELL LINE, TUMOR; CHROMOSOME MAPPING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; COMBINATORIAL CHEMISTRY TECHNIQUES; EPISTASIS, GENETIC; HELA CELLS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; NEOPLASM PROTEINS;

EID: 85015668248     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.4225     Document Type: Article

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