-
1
-
-
69249137029
-
Biological determinants of endocrine resistance in breast cancer
-
Musgrove EA, Sutherland RL. Biological determinants of endocrine resistance in breast cancer. Nat Rev Cancer. 2009;9(9):631-43.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.9
, pp. 631-643
-
-
Musgrove, E.A.1
Sutherland, R.L.2
-
2
-
-
79551576468
-
Mechanisms of endocrine resistance in breast cancer
-
Osborne CK, Schiff R. Mechanisms of endocrine resistance in breast cancer. Annu Rev Med. 2011;62:233-47.
-
(2011)
Annu Rev Med
, vol.62
, pp. 233-247
-
-
Osborne, C.K.1
Schiff, R.2
-
3
-
-
51049118140
-
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer
-
Stemke-Hale K, Gonzalez-Angulo AM, Lluch A, Neve RM, Kuo WL, Davies M, Carey M, Hu Z, Guan Y, Sahin A, et al. An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. Cancer Res. 2008;68(15):6084-91.
-
(2008)
Cancer Res
, vol.68
, Issue.15
, pp. 6084-6091
-
-
Stemke-Hale, K.1
Gonzalez-Angulo, A.M.2
Lluch, A.3
Neve, R.M.4
Kuo, W.L.5
Davies, M.6
Carey, M.7
Hu, Z.8
Guan, Y.9
Sahin, A.10
-
4
-
-
77951295615
-
Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines
-
Hollestelle A, Nagel JH, Smid M, Lam S, Elstrodt F, Wasielewski M, Ng SS, French PJ, Peeters JK, Rozendaal MJ, et al. Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines. Breast Cancer Res Treat. 2010;121(1):53-64.
-
(2010)
Breast Cancer Res Treat
, vol.121
, Issue.1
, pp. 53-64
-
-
Hollestelle, A.1
Nagel, J.H.2
Smid, M.3
Lam, S.4
Elstrodt, F.5
Wasielewski, M.6
Ng, S.S.7
French, P.J.8
Peeters, J.K.9
Rozendaal, M.J.10
-
5
-
-
84946040120
-
COSMIC: exploring the world's knowledge of somatic mutations in human cancer
-
Forbes SA, Beare D, Gunasekaran P, Leung K, Bindal N, Boutselakis H, Ding M, Bamford S, Cole C, Ward S, et al. COSMIC: exploring the world's knowledge of somatic mutations in human cancer. Nucleic Acids Res. 2015;43(Database issue):D805-11.
-
(2015)
Nucleic Acids Res
, vol.43
, Issue.DATABASE ISSUE
, pp. D805-D811
-
-
Forbes, S.A.1
Beare, D.2
Gunasekaran, P.3
Leung, K.4
Bindal, N.5
Boutselakis, H.6
Ding, M.7
Bamford, S.8
Cole, C.9
Ward, S.10
-
6
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A. 2003;100(14):8418-23.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.14
, pp. 8418-8423
-
-
Sorlie, T.1
Tibshirani, R.2
Parker, J.3
Hastie, T.4
Marron, J.S.5
Nobel, A.6
Deng, S.7
Johnsen, H.8
Pesich, R.9
Geisler, S.10
-
7
-
-
84863115693
-
Subtype and pathway specific responses to anticancer compounds in breast cancer
-
Heiser LM, Sadanandam A, Kuo WL, Benz SC, Goldstein TC, Ng S, Gibb WJ, Wang NJ, Ziyad S, Tong F, et al. Subtype and pathway specific responses to anticancer compounds in breast cancer. Proc Natl Acad Sci U S A. 2012;109(8):2724-9.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.8
, pp. 2724-2729
-
-
Heiser, L.M.1
Sadanandam, A.2
Kuo, W.L.3
Benz, S.C.4
Goldstein, T.C.5
Ng, S.6
Gibb, W.J.7
Wang, N.J.8
Ziyad, S.9
Tong, F.10
-
8
-
-
77953198056
-
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer
-
Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, Fitzgibbons PL, Francis G, Goldstein NS, Hayes M, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. Arch Pathol Lab Med. 2010;134(6):907-22.
-
(2010)
Arch Pathol Lab Med
, vol.134
, Issue.6
, pp. 907-922
-
-
Hammond, M.E.1
Hayes, D.F.2
Dowsett, M.3
Allred, D.C.4
Hagerty, K.L.5
Badve, S.6
Fitzgibbons, P.L.7
Francis, G.8
Goldstein, N.S.9
Hayes, M.10
-
9
-
-
84860214990
-
Intra-tumour heterogeneity: a looking glass for cancer?
-
Marusyk A, Almendro V, Polyak K. Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer. 2012;12(5):323-34.
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.5
, pp. 323-334
-
-
Marusyk, A.1
Almendro, V.2
Polyak, K.3
-
10
-
-
77949271600
-
Management of breast cancer with targeted agents: importance of heterogeneity. [corrected]
-
Di Cosimo S, Baselga J. Management of breast cancer with targeted agents: importance of heterogeneity. [corrected]. Nat Rev Clin Oncol. 2010;7(3):139-47.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, Issue.3
, pp. 139-147
-
-
Cosimo, S.1
Baselga, J.2
-
11
-
-
84655161946
-
HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression
-
Keith B, Johnson RS, Simon MC. HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression. Nat Rev Cancer. 2011;12(1):9-22.
-
(2011)
Nat Rev Cancer
, vol.12
, Issue.1
, pp. 9-22
-
-
Keith, B.1
Johnson, R.S.2
Simon, M.C.3
-
12
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW, Giaccia AJ. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature. 1996;379(6560):88-91.
-
(1996)
Nature
, vol.379
, Issue.6560
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
Housman, D.E.4
Koch, C.J.5
Lowe, S.W.6
Giaccia, A.J.7
-
13
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
Erler JT, Bennewith KL, Nicolau M, Dornhofer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ. Lysyl oxidase is essential for hypoxia-induced metastasis. Nature. 2006;440(7088):1222-6.
-
(2006)
Nature
, vol.440
, Issue.7088
, pp. 1222-1226
-
-
Erler, J.T.1
Bennewith, K.L.2
Nicolau, M.3
Dornhofer, N.4
Kong, C.5
Le, Q.T.6
Chi, J.T.7
Jeffrey, S.S.8
Giaccia, A.J.9
-
14
-
-
10444287596
-
Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis
-
Bindra RS, Glazer PM. Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis. Mutat Res. 2005;569(1-2):75-85.
-
(2005)
Mutat Res
, vol.569
, Issue.1-2
, pp. 75-85
-
-
Bindra, R.S.1
Glazer, P.M.2
-
15
-
-
15244344206
-
HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression
-
Koshiji M, To KK, Hammer S, Kumamoto K, Harris AL, Modrich P, Huang LE. HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression. Mol Cell. 2005;17(6):793-803.
-
(2005)
Mol Cell
, vol.17
, Issue.6
, pp. 793-803
-
-
Koshiji, M.1
To, K.K.2
Hammer, S.3
Kumamoto, K.4
Harris, A.L.5
Modrich, P.6
Huang, L.E.7
-
16
-
-
84859445000
-
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
-
Semenza GL. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. Trends Pharmacol Sci. 2012;33(4):207-14.
-
(2012)
Trends Pharmacol Sci
, vol.33
, Issue.4
, pp. 207-214
-
-
Semenza, G.L.1
-
17
-
-
0034321578
-
Blood supply, oxygenation status and metabolic micromilieu of breast cancers: characterization and therapeutic relevance
-
Vaupel P, Hockel M. Blood supply, oxygenation status and metabolic micromilieu of breast cancers: characterization and therapeutic relevance. Int J Oncol. 2000;17(5):869-79.
-
(2000)
Int J Oncol
, vol.17
, Issue.5
, pp. 869-879
-
-
Vaupel, P.1
Hockel, M.2
-
18
-
-
34247528557
-
Hypoxia and metastasis in breast cancer
-
Chaudary N, Hill RP. Hypoxia and metastasis in breast cancer. Breast Dis. 2006;26:55-64.
-
(2006)
Breast Dis
, vol.26
, pp. 55-64
-
-
Chaudary, N.1
Hill, R.P.2
-
19
-
-
80053355093
-
How can we overcome tumor hypoxia in radiation therapy?
-
Harada H. How can we overcome tumor hypoxia in radiation therapy? J Radiat Res. 2011;52(5):545-56.
-
(2011)
J Radiat Res
, vol.52
, Issue.5
, pp. 545-556
-
-
Harada, H.1
-
20
-
-
33646550165
-
Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells
-
Connolly E, Braunstein S, Formenti S, Schneider RJ. Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells. Mol Cell Biol. 2006;26(10):3955-65.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.10
, pp. 3955-3965
-
-
Connolly, E.1
Braunstein, S.2
Formenti, S.3
Schneider, R.J.4
-
21
-
-
78649375395
-
Translational regulation of gene expression during conditions of cell stress
-
Spriggs KA, Bushell M, Willis AE. Translational regulation of gene expression during conditions of cell stress. Mol Cell. 2010;40(2):228-37.
-
(2010)
Mol Cell
, vol.40
, Issue.2
, pp. 228-237
-
-
Spriggs, K.A.1
Bushell, M.2
Willis, A.E.3
-
22
-
-
22544464403
-
Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha
-
Chan DA, Sutphin PD, Yen SE, Giaccia AJ. Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha. Mol Cell Biol. 2005;25(15):6415-26.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.15
, pp. 6415-6426
-
-
Chan, D.A.1
Sutphin, P.D.2
Yen, S.E.3
Giaccia, A.J.4
-
23
-
-
0037131271
-
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha
-
Chan DA, Sutphin PD, Denko NC, Giaccia AJ. Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha. J Biol Chem. 2002;277(42):40112-17.
-
(2002)
J Biol Chem
, vol.277
, Issue.42
, pp. 40112-40117
-
-
Chan, D.A.1
Sutphin, P.D.2
Denko, N.C.3
Giaccia, A.J.4
-
25
-
-
10644234769
-
The role of hypoxia-induced factors in tumor progression
-
Vaupel P. The role of hypoxia-induced factors in tumor progression. Oncologist. 2004;9 Suppl 5:10-7.
-
(2004)
Oncologist
, vol.9
, pp. 10-17
-
-
Vaupel, P.1
-
26
-
-
33751192872
-
Regulation of angiogenesis by hypoxia and hypoxia-inducible factors
-
Hickey MM, Simon MC. Regulation of angiogenesis by hypoxia and hypoxia-inducible factors. Curr Top Dev Biol. 2006;76:217-57.
-
(2006)
Curr Top Dev Biol
, vol.76
, pp. 217-257
-
-
Hickey, M.M.1
Simon, M.C.2
-
27
-
-
33748037026
-
Hypoxia-inducible factor-1alpha expression predicts a poor response to primary chemoendocrine therapy and disease-free survival in primary human breast cancer
-
Generali D, Berruti A, Brizzi MP, Campo L, Bonardi S, Wigfield S, Bersiga A, Allevi G, Milani M, Aguggini S, et al. Hypoxia-inducible factor-1alpha expression predicts a poor response to primary chemoendocrine therapy and disease-free survival in primary human breast cancer. Clin Cancer Res. 2006;12(15):4562-8.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.15
, pp. 4562-4568
-
-
Generali, D.1
Berruti, A.2
Brizzi, M.P.3
Campo, L.4
Bonardi, S.5
Wigfield, S.6
Bersiga, A.7
Allevi, G.8
Milani, M.9
Aguggini, S.10
-
28
-
-
11144231029
-
Intermittent hypoxia induces proteasome-dependent down-regulation of estrogen receptor alpha in human breast carcinoma
-
Cooper C, Liu GY, Niu YL, Santos S, Murphy LC, Watson PH. Intermittent hypoxia induces proteasome-dependent down-regulation of estrogen receptor alpha in human breast carcinoma. Clin Cancer Res. 2004;10(24):8720-7.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.24
, pp. 8720-8727
-
-
Cooper, C.1
Liu, G.Y.2
Niu, Y.L.3
Santos, S.4
Murphy, L.C.5
Watson, P.H.6
-
29
-
-
27144501505
-
ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells
-
Kronblad A, Hedenfalk I, Nilsson E, Pahlman S, Landberg G. ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells. Oncogene. 2005;24(45):6835-41.
-
(2005)
Oncogene
, vol.24
, Issue.45
, pp. 6835-6841
-
-
Kronblad, A.1
Hedenfalk, I.2
Nilsson, E.3
Pahlman, S.4
Landberg, G.5
-
30
-
-
79955033732
-
Hypoxia-inducible factor 1 alpha represses the transcription of the estrogen receptor alpha gene in human breast cancer cells
-
Ryu K, Park C, Lee Y. Hypoxia-inducible factor 1 alpha represses the transcription of the estrogen receptor alpha gene in human breast cancer cells. Biochem Biophys Res Commun. 2011;407(4):831-6.
-
(2011)
Biochem Biophys Res Commun
, vol.407
, Issue.4
, pp. 831-836
-
-
Ryu, K.1
Park, C.2
Lee, Y.3
-
31
-
-
0036795452
-
Hypoxia induces proteasome-dependent degradation of estrogen receptor alpha in ZR-75 breast cancer cells
-
Stoner M, Saville B, Wormke M, Dean D, Burghardt R, Safe S. Hypoxia induces proteasome-dependent degradation of estrogen receptor alpha in ZR-75 breast cancer cells. Mol Endocrinol. 2002;16(10):2231-42.
-
(2002)
Mol Endocrinol
, vol.16
, Issue.10
, pp. 2231-2242
-
-
Stoner, M.1
Saville, B.2
Wormke, M.3
Dean, D.4
Burghardt, R.5
Safe, S.6
-
32
-
-
33845191779
-
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
-
Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, Kuo WL, Lapuk A, Neve RM, Qian Z, Ryder T, et al. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell. 2006;10(6):529-41.
-
(2006)
Cancer Cell
, vol.10
, Issue.6
, pp. 529-541
-
-
Chin, K.1
DeVries, S.2
Fridlyand, J.3
Spellman, P.T.4
Roydasgupta, R.5
Kuo, W.L.6
Lapuk, A.7
Neve, R.M.8
Qian, Z.9
Ryder, T.10
-
33
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, Clark L, Bayani N, Coppe JP, Tong F, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell. 2006;10(6):515-27.
-
(2006)
Cancer Cell
, vol.10
, Issue.6
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
Clark, L.7
Bayani, N.8
Coppe, J.P.9
Tong, F.10
-
34
-
-
65649138377
-
Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment
-
Chan DA, Kawahara TL, Sutphin PD, Chang HY, Chi JT, Giaccia AJ. Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. Cancer Cell. 2009;15(6):527-38.
-
(2009)
Cancer Cell
, vol.15
, Issue.6
, pp. 527-538
-
-
Chan, D.A.1
Kawahara, T.L.2
Sutphin, P.D.3
Chang, H.Y.4
Chi, J.T.5
Giaccia, A.J.6
-
35
-
-
0033313939
-
HMG-1 stimulates estrogen response element binding by estrogen receptor from stably transfected HeLa cells
-
Zhang CC, Krieg S, Shapiro DJ. HMG-1 stimulates estrogen response element binding by estrogen receptor from stably transfected HeLa cells. Mol Endocrinol. 1999;13(4):632-43.
-
(1999)
Mol Endocrinol
, vol.13
, Issue.4
, pp. 632-643
-
-
Zhang, C.C.1
Krieg, S.2
Shapiro, D.J.3
-
36
-
-
0033514930
-
Proteasome-dependent degradation of the human estrogen receptor
-
Nawaz Z, Lonard DM, Dennis AP, Smith CL, O'Malley BW. Proteasome-dependent degradation of the human estrogen receptor. Proc Natl Acad Sci U S A. 1999;96(5):1858-62.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, Issue.5
, pp. 1858-1862
-
-
Nawaz, Z.1
Lonard, D.M.2
Dennis, A.P.3
Smith, C.L.4
O'Malley, B.W.5
-
37
-
-
84890909102
-
Links between oestrogen receptor activation and proteolysis: relevance to hormone-regulated cancer therapy
-
Zhou W, Slingerland JM. Links between oestrogen receptor activation and proteolysis: relevance to hormone-regulated cancer therapy. Nat Rev Cancer. 2014;14(1):26-38.
-
(2014)
Nat Rev Cancer
, vol.14
, Issue.1
, pp. 26-38
-
-
Zhou, W.1
Slingerland, J.M.2
-
38
-
-
33846652552
-
Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression
-
Liao D, Corle C, Seagroves TN, Johnson RS. Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression. Cancer Res. 2007;67(2):563-72.
-
(2007)
Cancer Res
, vol.67
, Issue.2
, pp. 563-572
-
-
Liao, D.1
Corle, C.2
Seagroves, T.N.3
Johnson, R.S.4
-
39
-
-
32944456143
-
Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions
-
Kaper F, Dornhoefer N, Giaccia AJ. Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions. Cancer Res. 2006;66(3):1561-9.
-
(2006)
Cancer Res
, vol.66
, Issue.3
, pp. 1561-1569
-
-
Kaper, F.1
Dornhoefer, N.2
Giaccia, A.J.3
-
40
-
-
79960359071
-
Translational control is a major contributor to hypoxia induced gene expression
-
van den Beucken T, Magagnin MG, Jutten B, Seigneuric R, Lambin P, Koritzinsky M, Wouters BG. Translational control is a major contributor to hypoxia induced gene expression. Radiother Oncol. 2011;99(3):379-84.
-
(2011)
Radiother Oncol
, vol.99
, Issue.3
, pp. 379-384
-
-
Beucken, T.1
Magagnin, M.G.2
Jutten, B.3
Seigneuric, R.4
Lambin, P.5
Koritzinsky, M.6
Wouters, B.G.7
-
41
-
-
47749141892
-
Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism
-
Young RM, Wang SJ, Gordan JD, Ji X, Liebhaber SA, Simon MC. Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism. J Biol Chem. 2008;283(24):16309-19.
-
(2008)
J Biol Chem
, vol.283
, Issue.24
, pp. 16309-16319
-
-
Young, R.M.1
Wang, S.J.2
Gordan, J.D.3
Ji, X.4
Liebhaber, S.A.5
Simon, M.C.6
-
42
-
-
33746020276
-
Hypoxic activation of unoccupied estrogen-receptor-alpha is mediated by hypoxia-inducible factor-1 alpha
-
Cho J, Bahn JJ, Park M, Ahn W, Lee YJ. Hypoxic activation of unoccupied estrogen-receptor-alpha is mediated by hypoxia-inducible factor-1 alpha. J Steroid Biochem Mol Biol. 2006;100(1-3):18-23.
-
(2006)
J Steroid Biochem Mol Biol
, vol.100
, Issue.1-3
, pp. 18-23
-
-
Cho, J.1
Bahn, J.J.2
Park, M.3
Ahn, W.4
Lee, Y.J.5
-
43
-
-
57849097049
-
Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner
-
Yi JM, Kwon HY, Cho JY, Lee YJ. Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner. Biochem Biophys Res Commun. 2009;378(4):842-6.
-
(2009)
Biochem Biophys Res Commun
, vol.378
, Issue.4
, pp. 842-846
-
-
Yi, J.M.1
Kwon, H.Y.2
Cho, J.Y.3
Lee, Y.J.4
-
44
-
-
17844400028
-
Cobalt chloride-induced estrogen receptor alpha down-regulation involves hypoxia-inducible factor-1alpha in MCF-7 human breast cancer cells
-
Cho J, Kim D, Lee S, Lee Y. Cobalt chloride-induced estrogen receptor alpha down-regulation involves hypoxia-inducible factor-1alpha in MCF-7 human breast cancer cells. Mol Endocrinol. 2005;19(5):1191-9.
-
(2005)
Mol Endocrinol
, vol.19
, Issue.5
, pp. 1191-1199
-
-
Cho, J.1
Kim, D.2
Lee, S.3
Lee, Y.4
-
45
-
-
33746221325
-
Chronic hypoxia in the human neuroblastoma SH-SY5Y causes reduced expression of the putative alpha-secretases, ADAM10 and TACE, without altering their mRNA levels
-
Marshall AJ, Rattray M, Vaughan PF. Chronic hypoxia in the human neuroblastoma SH-SY5Y causes reduced expression of the putative alpha-secretases, ADAM10 and TACE, without altering their mRNA levels. Brain Res. 2006;1099(1):18-24.
-
(2006)
Brain Res
, vol.1099
, Issue.1
, pp. 18-24
-
-
Marshall, A.J.1
Rattray, M.2
Vaughan, P.F.3
-
46
-
-
84883534196
-
MYC degradation under low O2 tension promotes survival by evading hypoxia-induced cell death
-
Wong WJ, Qiu B, Nakazawa MS, Qing G, Simon MC. MYC degradation under low O2 tension promotes survival by evading hypoxia-induced cell death. Mol Cell Biol. 2013;33(17):3494-504.
-
(2013)
Mol Cell Biol
, vol.33
, Issue.17
, pp. 3494-3504
-
-
Wong, W.J.1
Qiu, B.2
Nakazawa, M.S.3
Qing, G.4
Simon, M.C.5
-
47
-
-
65549139358
-
The ubiquitin ligase Siah2 and the hypoxia response
-
Nakayama K, Qi J, Ronai Z. The ubiquitin ligase Siah2 and the hypoxia response. Mol Cancer Res. 2009;7(4):443-51.
-
(2009)
Mol Cancer Res
, vol.7
, Issue.4
, pp. 443-451
-
-
Nakayama, K.1
Qi, J.2
Ronai, Z.3
-
48
-
-
84893465244
-
Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth
-
Sun RC, Denko NC. Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth. Cell Metab. 2014;19(2):285-92.
-
(2014)
Cell Metab
, vol.19
, Issue.2
, pp. 285-292
-
-
Sun, R.C.1
Denko, N.C.2
-
49
-
-
22944444536
-
Hypoxia alters cathepsin B / inhibitor profiles in oral carcinoma cell lines
-
Wickramasinghe NS, Banerjee K, Nagaraj NS, Vigneswaran N, Zacharias W. Hypoxia alters cathepsin B / inhibitor profiles in oral carcinoma cell lines. Anticancer Res. 2005;25(4):2841-9.
-
(2005)
Anticancer Res
, vol.25
, Issue.4
, pp. 2841-2849
-
-
Wickramasinghe, N.S.1
Banerjee, K.2
Nagaraj, N.S.3
Vigneswaran, N.4
Zacharias, W.5
-
50
-
-
0027215039
-
Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo
-
Rami A, Krieglstein J. Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo. Brain Res. 1993;609(1-2):67-70.
-
(1993)
Brain Res
, vol.609
, Issue.1-2
, pp. 67-70
-
-
Rami, A.1
Krieglstein, J.2
-
51
-
-
84896282902
-
Calpain protease causes hypoxia-induced proteolysis in cultured human retina
-
Azuma M, Hammond KB, Nakajima E, Shearer TR. Calpain protease causes hypoxia-induced proteolysis in cultured human retina. Curr Eye Res. 2014;39(4):421-4.
-
(2014)
Curr Eye Res
, vol.39
, Issue.4
, pp. 421-424
-
-
Azuma, M.1
Hammond, K.B.2
Nakajima, E.3
Shearer, T.R.4
-
52
-
-
33947120556
-
Hypoxia-induced cell death of HepG2 cells involves a necrotic cell death mediated by calpain
-
Kim MJ, Oh SJ, Park SH, Kang HJ, Won MH, Kang TC, Hwang IK, Park JB, Kim JI, Kim J, et al. Hypoxia-induced cell death of HepG2 cells involves a necrotic cell death mediated by calpain. Apoptosis. 2007;12(4):707-18.
-
(2007)
Apoptosis
, vol.12
, Issue.4
, pp. 707-718
-
-
Kim, M.J.1
Oh, S.J.2
Park, S.H.3
Kang, H.J.4
Won, M.H.5
Kang, T.C.6
Hwang, I.K.7
Park, J.B.8
Kim, J.I.9
Kim, J.10
-
53
-
-
84926137241
-
Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase
-
Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, Gao R, Zhou C, Cao L, Liu J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17(1):95-103.
-
(2015)
Nat Cell Biol
, vol.17
, Issue.1
, pp. 95-103
-
-
Ma, B.1
Chen, Y.2
Chen, L.3
Cheng, H.4
Mu, C.5
Li, J.6
Gao, R.7
Zhou, C.8
Cao, L.9
Liu, J.10
-
54
-
-
84893745114
-
Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer
-
Kong W, He L, Richards EJ, Challa S, Xu CX, Permuth-Wey J, Lancaster JM, Coppola D, Sellers TA, Djeu JY, et al. Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer. Oncogene. 2014;33(6):679-89.
-
(2014)
Oncogene
, vol.33
, Issue.6
, pp. 679-689
-
-
Kong, W.1
He, L.2
Richards, E.J.3
Challa, S.4
Xu, C.X.5
Permuth-Wey, J.6
Lancaster, J.M.7
Coppola, D.8
Sellers, T.A.9
Djeu, J.Y.10
-
55
-
-
84874629159
-
Hypoxia-regulated microRNAs in human cancer
-
Shen G, Li X, Jia YF, Piazza GA, Xi Y. Hypoxia-regulated microRNAs in human cancer. Acta Pharmacol Sin. 2013;34(3):336-41.
-
(2013)
Acta Pharmacol Sin
, vol.34
, Issue.3
, pp. 336-341
-
-
Shen, G.1
Li, X.2
Jia, Y.F.3
Piazza, G.A.4
Xi, Y.5
-
56
-
-
80052221592
-
Interplay between HDAC3 and WDR5 is essential for hypoxia-induced epithelial-mesenchymal transition
-
Wu MZ, Tsai YP, Yang MH, Huang CH, Chang SY, Chang CC, Teng SC, Wu KJ. Interplay between HDAC3 and WDR5 is essential for hypoxia-induced epithelial-mesenchymal transition. Mol Cell. 2011;43(5):811-22.
-
(2011)
Mol Cell
, vol.43
, Issue.5
, pp. 811-822
-
-
Wu, M.Z.1
Tsai, Y.P.2
Yang, M.H.3
Huang, C.H.4
Chang, S.Y.5
Chang, C.C.6
Teng, S.C.7
Wu, K.J.8
-
57
-
-
84870864376
-
Estrogen receptor alpha is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions
-
Jung YS, Lee SJ, Yoon MH, Ha NC, Park BJ. Estrogen receptor alpha is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions. Cell Cycle. 2012;11(23):4462-73.
-
(2012)
Cell Cycle
, vol.11
, Issue.23
, pp. 4462-4473
-
-
Jung, Y.S.1
Lee, S.J.2
Yoon, M.H.3
Ha, N.C.4
Park, B.J.5
-
58
-
-
84855644497
-
Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia
-
Hofstetter CP, Burkhardt JK, Shin BJ, Gursel DB, Mubita L, Gorrepati R, Brennan C, Holland EC, Boockvar JA. Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia. PLoS One. 2012;7(1), e30059.
-
(2012)
PLoS One
, vol.7
, Issue.1
-
-
Hofstetter, C.P.1
Burkhardt, J.K.2
Shin, B.J.3
Gursel, D.B.4
Mubita, L.5
Gorrepati, R.6
Brennan, C.7
Holland, E.C.8
Boockvar, J.A.9
-
59
-
-
84899906671
-
Vascular measurements correlate with estrogen receptor status
-
Lloyd MC, Alfarouk KO, Verduzco D, Bui MM, Gillies RJ, Ibrahim ME, Brown JS, Gatenby RA. Vascular measurements correlate with estrogen receptor status. BMC Cancer. 2014;14:279.
-
(2014)
BMC Cancer
, vol.14
, pp. 279
-
-
Lloyd, M.C.1
Alfarouk, K.O.2
Verduzco, D.3
Bui, M.M.4
Gillies, R.J.5
Ibrahim, M.E.6
Brown, J.S.7
Gatenby, R.A.8
|