From oxygen to erythropoietin: Relevance of hypoxia for retinal development, health and disease
Caprara C, Grimm C. From oxygen to erythropoietin: relevance of hypoxia for retinal development, health and disease. Prog Retin Eye Res 2012;31:89-119.
Involvement of calpain isoforms in ischemia-reperfusion injury in rat retina
Sakamoto Y, Nakajima T, Fukiage C, Sakai O, Yoshida Y, Azuma M, et al. Involvement of calpain isoforms in ischemia-reperfusion injury in rat retina. Curr Eye Res 2000;21:571-580.
Amelioration of retinal degeneration and proteolysis in acute ocular hypertensive rats by calpain inhibitor ((1S)-1-((((1S)-1-benzyl-3- cyclopropylamino- 23-di-oxopropyl) amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester
Oka T, Walkup RD, Tamada Y, Nakajima E, Tochigi A, Shearer TR, et al. Amelioration of retinal degeneration and proteolysis in acute ocular hypertensive rats by calpain inhibitor ((1S)-1-((((1S)-1-benzyl-3- cyclopropylamino- 2,3-di-oxopropyl) amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester. Neuroscience 2006;141:2139-2145.
Involvement of calpain in hypoxia-induced damage in rat retina in vitro
Tamada Y, Fukiage C, Daibo S, Yoshida Y, Azuma M, Shearer TR. Involvement of calpain in hypoxia-induced damage in rat retina in vitro. Comp Biochem Physiol B Biochem Mol Biol 2002;131:221-225.
Calpain-specific proteolysis in primate retina: Contribution of calpains in cell death
Nakajima E, David LL, Bystrom C, Shearer TR, Azuma M. Calpain-specific proteolysis in primate retina: contribution of calpains in cell death. Invest Ophthalmol Vis Sci 2006;47: 5469-5475.
Calpain, not caspase, is the causative protease for hypoxic damage in cultured monkey retinal cells
Nakajima E, Hammond KB, Rosales JL, Shearer TR, Azuma M. Calpain, not caspase, is the causative protease for hypoxic damage in cultured monkey retinal cells. Invest Ophthalmol Vis Sci 2011;52:7059-7067.
Retinal penetration of calpain inhibitors in rats after oral administration
Shirasaki Y, Yamaguchi M, Miyashita H. Retinal penetration of calpain inhibitors in rats after oral administration. J Ocul Pharmacol Ther 2006;22:417-424.
Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains
Moldoveanu T, Gehring K, Green DR. Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains. Nature 2008;20: 404-408.