Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 11, 2017, Pages E2243-E2252

  Ehrlich, Marc ^a,b   Mozafari, Sabah ^c,d,e,f   Glatza, Michael ^b   Starost, Laura ^a,b   Velychko, Sergiy ^b   Hallmann, Anna Lena ^a,b   Cui, Qiao Ling ^g   Schambach, Axel ^h   Kim, Kee Pyo ^b   Bachelin, Corinne ^c,d,e,f   Marteyn, Antoine ^c,d,e,f   Hargus, Gunnar ^a,b   Johnson, Radia Marie ⁱ   Antel, Jack ^g   Sterneckert, Jared ^j   Zaehres, Holm ^b,k   Schöler, Hans R ^b,l   Baron Van Evercooren, Anne ^c,d,e,f   Kuhlmann, Tanja ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^c INSERM   (France)

^d CNRS   (France)

^e SORBONNE UNIVERSITÉ   (France)

^f INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

^g MCGILL UNIVERSITY   (Canada)

^h HANNOVER MEDICAL SCHOOL   (Germany)

ⁱ MCGILL UNIVERSITY   (Canada)

^j CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^k RUHR UNIVERSITY BOCHUM   (Germany)

^l UNIVERSITY OF MÜNSTER   (Germany)

more..

Author keywords

Disease modeling; Forward patterning; Human iPSC; Myelination; Oligodendrocytes

Indexed keywords

MYELIN; MYELIN BASIC PROTEIN; NUCLEIC ACID BINDING PROTEIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; RAG2 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX6.2; TRANSCRIPTION FACTOR SOX10; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; TAU PROTEIN; TRANSCRIPTOME;

ADULT; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEMYELINATION; EMBRYO; GENE EXPRESSION; GENE EXPRESSION PROFILING; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INDUCED PLURIPOTENT STEM CELL; MYELINATION; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; ANIMAL; BRAIN; CELL CULTURE; CELL DEATH; CELL LINEAGE; CLUSTER ANALYSIS; CYTOLOGY; DEMYELINATING DISEASE; DISEASE MODEL; ECTOPIC EXPRESSION; GENETICS; METABOLISM; MOUSE; MUTATION; MYELIN SHEATH; OXIDATIVE STRESS; PATHOLOGY; SPINAL CORD; ULTRASTRUCTURE;

ANIMALS; BIOMARKERS; BRAIN; CELL DEATH; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; CLUSTER ANALYSIS; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; ECTOPIC GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MUTATION; MYELIN BASIC PROTEIN; MYELIN SHEATH; NEURAL STEM CELLS; OLIGODENDROGLIA; OXIDATIVE STRESS; SPINAL CORD; TAU PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTOME;

EID: 85015435247     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1614412114     Document Type: Article

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