Directing human neural stem/precursor cells into oligodendrocytes by overexpression of Olig2 transcription factor

Journal of Neuroscience Research

Volumn 87, Issue 15, 2009, Pages 3438-3446

  Maire, Cécile L ^a,b,c   Buchet, Delphine ^a,b,c   Kerninon, Christophe ^a,b,c   Deboux, Cyrille ^a,b,c   Evercooren, Anne Baron Van ^a,b,c,d   Nait Oumesmar, Brahim ^a,b,c,d  

^a SORBONNE UNIVERSITÉ   (France)

^b INSERM   (France)

^c CNRS   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Human fetal neural stem precursor cells; Myelination; Olig2; Oligodendrocytes; Shiverer

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; LENTIVIRUS VECTOR; MYELIN BASIC PROTEIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FATE; CELL MATURATION; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; DEMYELINATION; FETUS; GENE OVEREXPRESSION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MYELINATION; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION;

EID: 70449382853     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22194     Document Type: Article

References (49)

1. Avellana-Adalid V, Nait-Oumesmar B, Lachapelle F, Baron-Van Evercooren A. 1996. Expansion of rat oligodendrocyte progenitors into proliferative "oligospheres" that retain differentiation potential. J Neurosci Res 45:558-570.
2. Back SA, Luo NL, Borenstein NS, Levine JM, Volpe JJ, Kinney HC. 2001. Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury. J Neurosci 21:1302-1312.
3. Baron-Van Evercooren A, Blakemore W. 2004. Remyelination through engraftment in myelin biology and disordres. New York: Academic Press. p 143-162.
4. Billon N, Jolicoeur C, Ying QL, Smith A, Raff M. 2002. Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells. J Cell Sci 115:3657-3665.
5. Brüstle O, Spiro AC, Karram K, Choudhary K, Okabe S, McKay RD. 1997. In vitro-generated neural precursors participate in mammalian brain development. Proc Natl Acad Sci U S A 94:14809-14814.
6. Buchet D, Baron-Van Evercooren A. 2009. In search of human oligodendroglia for myelin repair. Neurosci Lett 456:112-119.
7. Cai J, Chen Y, Cai WH, Hurlock EC, Wu H, Kernie SG, Parada LF, Lu QR. 2007. A crucial role for Olig2 in white matter astrocyte development. Development 134:1887-1899. (Pubitemid 46939234)
8. Copray S, Balasubramaniyan V, Levenga J, de Bruijn J, Liem R, Boddeke E. 2006. Olig2 overexpression induces the in vitro differentiation of neural stem cells into mature oligodendrocytes. Stem Cells 24:1001-1010. (Pubitemid 44464733)
9. Eftekharpour E, Karimi-Abdolrezaee S, Wang J, El Beheiry H, Morshead C, Fehlings MG. 2007. Myelination of congenitally dysmyelinated spinal cord axons by adult neural precursor cells results in formation of nodes of Ranvier and improved axonal conduction. J Neurosci 27:3416-3428. (Pubitemid 46515125)
10. Flax JD, Aurora S, Yang C, Simonin C, Wills AM, Billinghurst LL, Jendoubi M, Sidman RL, Wolfe JH, Kim SU, Snyder EY. 1998. Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes. Nat Biotechnol 16:1033-1039. (Pubitemid 28515895)
11. Fricker RA, Carpenter MK, Winkler C, Greco C, Gates MA, Björklund A. 1999. Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain. J Neurosci 19:5990-6005. (Pubitemid 29327933)
12. Glaser T, Perez-Bouza A, Klein K, Brüstle O. 2005. Generation of purified oligodendrocyte progenitors from embryonic stem cells. FASEB J 19:112-114. (Pubitemid 40069935)
13. Goldman SA, Schanz S, Windrem MS. 2008. Stem cell-based strategies for treating pediatric disorders of myelin. Hum Mol Genet 17:R76-R83.
14. Gumpel M, Lachapelle F, Gansmuller A, Baulac M, Baron van Evercooren A, Baumann N. 1987. Transplantation of human embryonic oligodendrocytes into shiverer brain. Ann N Y Acad Sci 495:71-85. (Pubitemid 18119379)
15. Hajihosseini M, Tham TN, Dubois-Dalcq M. 1996. Origin of oligodendrocytes within the human spinal cord. J Neurosci 16:7981-7994. (Pubitemid 26405060)
16. Jakovcevski I, Zecevic N. 2005a. Sequence of oligodendrocyte development in the human fetal telencephalon. Glia 49:480-491. (Pubitemid 40353834)
17. Jakovcevski I, Zecevic N. 2005b. Olig transcription factors are expressed in oligodendrocyte and neuronal cells in human fetal CNS. J Neurosci 25:10064-10073. (Pubitemid 41636202)
18. Lachapelle F, Gumpel M, Baulac M, Jacque C, Duc P, Baumann N. 1983. Transplantation of CNS fragments into the brain of shiverer mutant mice: extensive myelination by implanted oligodendrocytes. I. Immunohistochemical studies. Dev Neurosci 6:325-334. (Pubitemid 15051599)
19. Lee SK, Lee B, Ruiz EC, Pfaff SL. 2005. Olig2 and Ngn2 function in opposition to modulate gene expression in motor neuron progenitor cells. Genes Dev 19:282-294. (Pubitemid 40111123)
20. Ligon KL, Alberta JA, Kho AT, Weiss J, Kwaan MR, Nutt CL, Louis DN, Stiles CD, Rowitch DH. 2004. The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. J Neuropathol Exp Neurol 63:499-509. (Pubitemid 38669670)
21. Liu S, Qu Y, Stewart TJ, Howard MJ, Chakrabortty S, Holekamp TF, McDonald JW. 2000. Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation. Proc Natl Acad Sci U S A 97:6126-6131. (Pubitemid 30367534)
22. Lu QR, Yuk D, Alberta JA, Zhu Z, Pawlitzky I, Chan J, McMahon AP, Stiles CD, Rowitch DH. 2000. Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron 25:317-329. (Pubitemid 30831788)
23. Lu QR, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, Rowitch DH. 2002. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell 109:75-86. (Pubitemid 34327518)
24. Martinez-Serrano A, Rubio FJ, Navarro B, Bueno C, Villa A. 2001. Human neural stem and progenitor cells: in vitro and in vivo properties, and potential for gene therapy and cell replacement in the CNS. Curr Gene Ther 1:279-299.
25. Mitome M, Low HP, van den Pol A, Nunnari JJ, Wolf MK, Billings- Gagliardi S, Schwartz WJ. 2001. Toward the reconstruction of central nervous system white matter using neural precursor cells. Brain 124:2147-2161. (Pubitemid 33055360)
26. Murray K, Dubois-Dalcq M. 1997. Emergence of oligodendrocytes from human neural spheres. J Neurosci Res 50:146-156. (Pubitemid 27473631)
27. Nunes MC, Roy NS, Keyoung HM, Goodman RR, McKhann G 2nd, Jiang L, Kang J, Nedergaard M, Goldman SA. 2003. Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain. Nat Med 9:439-447.
28. Parras CM, Hunt C, Sugimori M, Nakafuku M, Rowitch D, Guillemot F. 2007. The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. J Neurosci 27:4233-4242. (Pubitemid 46640707)
29. Quinones-Hinojosa A, Sanai N, Soriano-Navarro M, Gonzalez-Perez O, Mirzadeh Z, Gil-Perotin S, Romero-Rodriguez R, Berger MS, Garcia-Verdugo JM, Alvarez-Buylla A. 2006. Cellular composition and cytoarchitecture of the adult human subventricular zone: a niche of neural stem cells. J Comp Neurol 494:415-434. (Pubitemid 41794059)
30. Rakic S, Zecevic N. 2003. Early oligodendrocyte progenitor cells in the human fetal telencephalon. Glia 41:117-127. (Pubitemid 36262189)
31. Rowitch DH. 2004. Glial specification in the vertebrate neural tube. Nat Rev Neurosci 5:409-419.
32. Roy NS, Wang S, Harrison-Restelli C, Benraiss A, Fraser RA, Gravel M, Braun PE, Goldman SA. 1999. Identification, isolation, and promoter- defined separation of mitotic oligodendrocyte progenitor cells from the adult human subcortical white matter. J Neurosci 19:9986-9995. (Pubitemid 30226670)
33. Sanai N, Tramontin AD, Quinones-Hinojosa A, Barbaro NM, Gupta N, Kunwar S, Lawton MT, McDermott MW, Parsa AT, Garcia-Verdugo JM, Berger MS, Alvarez-Buylla A. 2004. Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration. Nature 427:740-744. (Pubitemid 38294593)
34. Seilhean D, Gansmüller A, Baron-Van Evercooren A, Gumpel M, Lachapelle F. 2006. Myelination by transplanted human and mouse central nervous system tissue after long-term cryopreservation. Acta Neuropathol 91:82-88.
35. Sugimori M, Nagao M, Bertrand N, Parras CM, Guillemot F, Nakafuku M. 2007. Combinatorial actions of patterning and HLH transcription factors in the spatiotemporal control of neurogenesis and gliogenesis in the developing spinal cord. Development 134:1617-1629. (Pubitemid 46746313)
36. Sun T, Echelard Y, Lu R, Yuk DI, Kaing S, Stiles CD, Rowitch DH. 2001. Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube. Curr Biol 11:1413-1420. (Pubitemid 32863190)
37. Takebayashi H, Nabeshima Y, Yoshida S, Chisaka O, Ikenaka K, Nabeshima Y. 2002. The basic helix-loop-helix factor olig2 is essential for the development of motoneuron and oligodendrocyte lineages. Curr Biol 12:1157-1163. (Pubitemid 34766941)
38. Tamaki S, Eckert K, He D, Sutton R, Doshe M, Jain G, Tushinski R, Reitsma M, Harris B, Tsukamoto A, Gage F, Weissman I, Uchida N. 2002. Engraftment of sorted/expanded human central nervous system stem cells from fetal brain. J Neurosci Res 69:976-986. (Pubitemid 34984715)
39. Vescovi AL, Gritti A, Galli R, Parati EA. 1999. Isolation and intracerebral grafting of nontransformed multipotential embryonic human CNS stem cells. J Neurotrauma 16:689-693. (Pubitemid 29422793)
40. Vitry S, Avellana-Adalid V, Hardy R, Lachapelle F, Baron-Van Evercooren A. 1999. Mouse oligospheres: from preprogenitors to functional oligodendrocytes. J Neurosci Res 58:735-751.
41. Warrington AE, Barbarese E, Pfeiffer SE. 1993. Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypomyelinating hosts. J Neurosci Res 34:1-13. (Pubitemid 23014249)
42. Windrem MS, Nunes MC, Rashbaum WK, Schwartz TH, Goodman RA, McKhann G 2nd, Roy NS, Goldman SA. 2004. Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain. Nat Med 10:93-97.
43. Windrem MS, Schanz SJ, Guo M, Tian GF, Washco V, Stanwood N, Rasband M, Roy NS, Nedergaard M, Havton LA, Wang S, Goldman SA. 2008. Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse. Cell Stem Cell 2:553-565. (Pubitemid 351729215)
44. Yandava BD, Billinghurst LL, Snyder EY. 1999. "Global" cell replacement is feasible via neural stem cell transplantation: evidence from the dysmyelinated shiverer mouse brain. Proc Natl Acad Sci U S A 96:7029-7034.
45. Zhang SC, Duncan ID. 2000. Remyelination and restoration of axonal function by glial cell transplantation. Prog Brain Res 127:515-533.
46. Zhang SC, Lundberg C, Lipsitz D, O'Connor LT, Duncan ID. 1998. Generation of oligodendroglial progenitors from neural stem cells. J Neurocytol 27:475-489. (Pubitemid 29204652)
47. Zhang SC, Wernig M, Duncan ID, Brüstle O, Thomson JA. 2001. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol 19:1129-1133.
48. Zhou Q, Anderson DJ. 2002. The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification. Cell 109:61-73. (Pubitemid 34327517)
49. Zhou Q, Choi G, Anderson DJ. 2001. The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2. Neuron 31:791-807. (Pubitemid 32907374)