Conformational stability of the epidermal growth factor (EGF) receptor as influenced by glycosylation, dimerization and EGF hormone binding

Proteins: Structure, Function and Bioinformatics

Volumn 85, Issue 4, 2017, Pages 561-570

  Taylor, Eric S ^a   Pol Fachin, Laercio ^b,c   Lins, Roberto D ^b,c   Lower, Steven K ^d  

^a KENT STATE UNIVERSITY   (United States)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

EGF binding; ErbB; glycoprotein; molecular dynamics

Indexed keywords

ASPARAGINE LINKED OLIGOSACCHARIDE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; ASPARAGINE; EGFR PROTEIN, HUMAN; N ACETYLGLUCOSAMINE; PROTEIN BINDING;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; DIMERIZATION; HORMONE BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; SURFACE AREA; CHEMISTRY; GLYCOSYLATION; HUMAN; PROTEIN MULTIMERIZATION; THERMODYNAMICS;

ACETYLGLUCOSAMINE; ASPARAGINE; BINDING SITES; EPIDERMAL GROWTH FACTOR; GLYCOSYLATION; HUMANS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; THERMODYNAMICS;

EID: 85015430525     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.25220     Document Type: Article

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