Staphylococcus aureus protein A mediates invasion across airway epithelial cells through activation of RhoA GTPase signaling and proteolytic activity

Journal of Biological Chemistry

Volumn 286, Issue 41, 2011, Pages 35891-35898

  Soong, Grace ^a   Martin, Francis J ^a   Chun, Jarin ^a   Cohen, Taylor S ^a   Ahn, Danielle S ^a   Prince, Alice ^a  

^a Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AIRWAY EPITHELIAL CELLS; BACTERIAL INVASION; CALPAINS; CELL-CELL JUNCTIONS; CYTOSKELETONS; E-CADHERINS; EPITHELIAL BARRIER; EPITHELIAL MONOLAYERS; HUMAN AIRWAY; IN-VIVO; MUCOSAL SURFACE; MULTIPLE RECEPTORS; OCCLUDIN; PROTEIN A; PROTEOLYTIC ACTIVITIES; RHOA GTPASE; S. AUREUS; SIGNALING CASCADES; STAPHYLOCOCCUS AUREUS PROTEIN A; SURFACE PROTEINS; WILD TYPES;

BACTERIA; CELL MEMBRANES; ENZYME ACTIVITY; MONOLAYERS; PRESSURE EFFECTS;

PROTEINS;

CALPAIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MEMBRANE PROTEIN; MYOSIN LIGHT CHAIN; OCCLUDIN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SURFACE PROTEIN A; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM MUTANT; CELL INVASION; CELL JUNCTION; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; EPITHELIUM CELL; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LUNG PARENCHYMA; MOLECULAR PATHOLOGY; MONOLAYER CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN INDUCTION; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFECTION; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; WILD TYPE;

ANIMALS; CADHERINS; CALPAIN; CELL LINE; FEMALE; HUMANS; INTERCELLULAR JUNCTIONS; MICE; MUTATION; PNEUMONIA, STAPHYLOCOCCAL; PROTEASE INHIBITORS; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RESPIRATORY MUCOSA; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; STAPHYLOCOCCAL PROTEIN A; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 80053921773     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.295386     Document Type: Article

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