N-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 14, 2015, Pages 4334-4339

  Kaszuba, Karol ^a   Grzybek, Michał ^b,c   Orłowski, Adam ^a   Danne, Reinis ^a   Róg, Tomasz ^a   Simons, Kai ^d   Coskun, Ünal ^b,c   Vattulainen, Ilpo ^a,e  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^d MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^e UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

EGFR; Lipid protein interaction; Lipids; MD simulation; Proteoliposomes

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EGFR PROTEIN, HUMAN; LIGAND; LIPID BILAYER; MONOCLONAL ANTIBODY; PROTEIN BINDING; PROTEOLIPID; PROTEOLIPOSOMES;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEGLYCOSYLATION; DISSOCIATION CONSTANT; HYDROGEN BOND; LIPID BILAYER; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; PROTEIN SECONDARY STRUCTURE; SIMULATION; WESTERN BLOTTING; CELL MEMBRANE; CHEMISTRY; COMPUTER SIMULATION; GLYCOSYLATION; HUMAN; METABOLISM; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE; SOFTWARE;

ANTIBODIES, MONOCLONAL; CELL MEMBRANE; COMPUTER SIMULATION; GLYCOSYLATION; HUMANS; LIGANDS; LIPID BILAYERS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEOLIPIDS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SOFTWARE;

EID: 84929500864     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1503262112     Document Type: Article

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