Production of taxadiene by engineering of mevalonate pathway in Escherichia coli and endophytic fungus Alternaria alternata TPF6

Biotechnology Journal

Volumn 12, Issue 4, 2017, Pages

  Bian, Guangkai ^a   Yuan, Yujie ^a   Tao, Hui ^a   Shi, Xiaofei ^a   Zhong, Xiaofang ^a   Han, Yichao ^b   Fu, Shuai ^b   Fang, Chengxiang ^a   Deng, Zixin ^a,c   Liu, Tiangang ^a,c  

^a WUHAN UNIVERSITY   (China)

^b Wuhan J1 Biotech Co Ltd   (China)

^c Centre for Biomedicine Research   (China)

Author keywords

Agrobacterium tumefaciens; Alternaria alternata TPF6; Mevalonate pathway; Taxadiene

Indexed keywords

BACTERIA; FUNGI;

AGROBACTERIUM TUMEFACIENS; AGROBACTERIUM TUMEFACIENS-MEDIATED TRANSFORMATION; ALTERNARIA ALTERNATA; HETEROLOGOUS PROMOTERS; ISOPENTENYL DIPHOSPHATE ISOMERASE (IDI); MEVALONATE PATHWAY; MICROBIAL PRODUCTION; TAXADIENES;

ESCHERICHIA COLI;

ALKADIENE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; ISOPENTENYL DIPHOSPHATE DELTA ISOMERASE; MEVALONIC ACID; PACLITAXEL DERIVATIVE; SYNTHETASE; TAXADIENE SYNTHASE; UNCLASSIFIED DRUG; ALKENE; DITERPENE; HIGH MOBILITY GROUP B1 PROTEIN; HMGB1 PROTEIN, HUMAN; ISOMERASE; ISOPENTENYLDIPHOSPHATE DELTA-ISOMERASE; TAXA-4(5),11(12)-DIENE SYNTHASE; TAXA-4(5),11(12)DIENE;

ALTERNARIA ALTERNATA; ALTERNARIA ALTERNATA TPF6; ARTICLE; BACTERIAL STRAIN; BACTERIUM MUTANT; BACTERIUM TRANSFORMATION; BIOENGINEERING; BIOMASS PRODUCTION; CONTROLLED STUDY; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; AGROBACTERIUM TUMEFACIENS; ALTERNARIA; BIOSYNTHESIS; ENDOPHYTE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLIC ENGINEERING; METABOLISM; NEOPLASMS;

AGROBACTERIUM TUMEFACIENS; ALKENES; ALTERNARIA; CARBON-CARBON DOUBLE BOND ISOMERASES; DITERPENES; ENDOPHYTES; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HMGB1 PROTEIN; HUMANS; ISOMERASES; METABOLIC ENGINEERING; MEVALONIC ACID; NEOPLASMS; TRANSFORMATION, BACTERIAL;

EID: 85015428801     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201600697     Document Type: Article

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