Multilineage transduction of resident lung cells in vivo by AAV2/8 for α1-antitrypsin gene therapy

Molecular Therapy Methods and Clinical Development

Volumn 3, Issue , 2016, Pages 16042-

  Payne, Julia G ^a,b   Takahashi, Ayuko ^c   Higgins, Michelle I ^a   Porter, Emily L ^a,b   Suki, Bela ^c   Balazs, Alejandro ^d   Wilson, Andrew A ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Boston University   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; ELASTASE; ELASTIN; FIREFLY LUCIFERASE; PANCREATIC ELASTASE; PHOSPHATE BUFFERED SALINE; ADENO ASSOCIATED VIRUS VECTOR;

ADENO ASSOCIATED VIRUS 2; ADENO ASSOCIATED VIRUS 8; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; BRONCHIOLE; CELL LINEAGE; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISEASE SEVERITY; EPITHELIAL LINING FLUID; EXPERIMENTAL EMPHYSEMA; FEMALE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HEMATOPOIETIC CELL; IMMUNOFLUORESCENCE TEST; IN VIVO GENE TRANSFER; IN VIVO STUDY; LIVER CELL; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM CELL; LUNG ALVEOLUS MACROPHAGE; LUNG COMPLIANCE; MOUSE; NONHUMAN; NONVIRAL GENE THERAPY; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENE; GENE THERAPY; LUNG FUNCTION; VASCULAR ENDOTHELIAL CELL;

EID: 85015205986     PISSN: None     EISSN: 23290501     Source Type: Journal    
DOI: 10.1038/mtm.2016.42     Document Type: Article

References (53)

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