Muscle-directed gene therapy for hemophilia B with more efficient and less immunogenic AAV vectors

Journal of Thrombosis and Haemostasis

Volumn 9, Issue 10, 2011, Pages 2009-2019

  Wang, L ^a   Louboutin, J P ^a   Bell, P ^a   Greig, J A ^a   Li, Y ^a   Wu, D ^a   Wilson, J M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Adeno associated viruses; Factor IX; Gene therapy; Hemophilia B; Muscle

Indexed keywords

ADENOVIRUS VECTOR; BLOOD CLOTTING FACTOR 9; BLOOD CLOTTING FACTOR 9 ANTIBODY; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; GENE EXPRESSION; GENE THERAPY; HEMOPHILIA B; IMMUNE RESPONSE; MALE; MOUSE; MUSCLE DIRECTED GENE THERAPY; NONHUMAN; PRIORITY JOURNAL; SEROTYPE; T LYMPHOCYTE; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID;

ANIMALS; DEPENDOVIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE THERAPY; GENETIC VECTORS; HEMOPHILIA B; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MUSCLES;

EID: 80053396582     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04491.x     Document Type: Article

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