Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss

Molecular Therapy Methods and Clinical Development

Volumn 2, Issue , 2015, Pages 15003-

  Cwerman Thibault, Hélène ^a,b,c   Augustin, Sébastien ^a,b,c   Lechauve, Christophe ^a,b,c   Ayache, Jessica ^a,b,c   Ellouze, Sami ^a,b,c   Sahel, José Alain ^a,b,c   Corral Debrinski, Marisol ^a,b,c  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENO ASSOCIATED VIRUS VECTOR; CIS ACTING ELEMENT; COX10 PROTEIN; CYTOCHROME C OXIDASE; MESSENGER RNA; MITOCHONDRIAL PROTEIN; ND4 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG; PROTEIN; PROTEIN COX10; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE SUBUNIT 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL MODEL; GENE SEQUENCE; GENE THERAPY; GENETIC TRANSCRIPTION; LEBER HEREDITARY OPTIC NEUROPATHY; MITOCHONDRION; NONHUMAN; OPTIC NERVE ATROPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RESPIRATORY CHAIN; RETINA GANGLION CELL; STABLE EXPRESSION; VISUAL IMPAIRMENT; CELLULAR DISTRIBUTION; CENTRAL SCOTOMA; GENE EXPRESSION; PROTEIN PROTEIN INTERACTION; RETINA DEGENERATION;

EID: 85015172194     PISSN: None     EISSN: 23290501     Source Type: Journal    
DOI: 10.1038/mtm.2015.3     Document Type: Article

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