Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes

Cell Systems

Volumn 4, Issue 4, 2017, Pages 404-415.e5

  Rhinn, Herve ^a   Abeliovich, Asa ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

aging; brain; genome wide association study; genomics; inflammaging; inflammation; microglia; progranulin; TMEM106B

Indexed keywords

TRANSCRIPTOME; GRN PROTEIN, HUMAN; MEMBRANE PROTEIN; NERVE PROTEIN; TMEM106B PROTEIN, HUMAN;

AGED; AGING; ARTICLE; AUTOPSY; BRAIN CORTEX; CELL LOSS; COGNITIVE DEFECT; COHORT ANALYSIS; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC RISK; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; GRN GENE; HUMAN; INFLAMMATION; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; REGULATORY MECHANISM; TMEM106B GENE; AGE; GENE EXPRESSION PROFILING; GENETICS; INNATE IMMUNITY; METABOLISM; NERVE DEGENERATION; PATHOLOGY; PHYSIOLOGY; VERY ELDERLY;

AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; CEREBRAL CORTEX; COHORT STUDIES; GENE EXPRESSION PROFILING; GENOME-WIDE ASSOCIATION STUDY; HUMANS; IMMUNITY, INNATE; MEMBRANE PROTEINS; NERVE DEGENERATION; NERVE TISSUE PROTEINS; PHENOTYPE; PROGRANULINS;

EID: 85015019999     PISSN: 24054712     EISSN: 24054720     Source Type: Journal    
DOI: 10.1016/j.cels.2017.02.009     Document Type: Article

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