The TMEM106B locus and TDP-43 pathology in older persons without FTLD (Neurology Neurology (2015) 84:927-934)

Neurology

Volumn 85, Issue 15, 2015, Pages 1354-1355

  Dickson, Dennis W ^a   Rademakers, Rosa ^a   Nicholson, Alexandra M ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TAR DNA BINDING PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; DISEASE ASSOCIATION; EDITORIAL; FRONTOTEMPORAL DEMENTIA; GENE; GENE LOCUS; GENETIC RISK; HIPPOCAMPAL SCLEROSIS; HUMAN; PRIORITY JOURNAL; TDP 43 PROTEINOPATHY; TMEM106B GENE; AGING; FEMALE; GENETICS; MALE;

AGING; FEMALE; FRONTOTEMPORAL LOBAR DEGENERATION; GENETIC LOCI; HUMANS; MALE; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; TDP-43 PROTEINOPATHIES;

EID: 84944401112     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/01.wnl.0000472918.79256.a9     Document Type: Editorial

References (5)

1. Yu L, De Jager PL, Yang J, et al. The TMEM106B locus and TDP-43 pathology in older persons without FTLD. Neurology 2015; 84: 927-934
2. Aoki N, Murray ME, Ogaki K, et al. Hippocampal sclerosis in Lewy body disease is a TDP-43 proteinopathy similar to FTLD-TDP Type A. Acta Neuropathol 2015; 129: 53-64
3. Rutherford NJ, Carrasquillo MM, Li M, et al. TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease. Neurology 2012; 79: 717-718
4. Nelson PT, Wang WX, Partch AB, et al. Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology. J Neuropathol Exp Neurol 2015; 74: 75-84
5. Lee EB, Lee VM, Trojanowski JQ, Neumann M. TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system. Acta Neuropathol 2008; 115: 305-311