Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin

Frontiers in Cellular and Infection Microbiology

Volumn 7, Issue FEB, 2017, Pages

  Speir, Mary ^a   Vogrin, Adam ^a   Seidi, Azadeh ^a   Abraham, Gilu ^a   Hunot, Stéphane ^b,c   Han, Qingqing ^b   Dorn, Gerald W ^d   Masters, Seth L ^e,f   Flavell, Richard A ^b   Vince, James E ^e,f   Naderer, Thomas ^a  

^a MONASH UNIVERSITY   (Australia)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CNRS   (France)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^f UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Bacteria; Caspases; Infection; Live cell imaging; Mitochondria; Pneumonia; Pyroptosis

Indexed keywords

CASPASE 11; CASPASE 3; CASPASE 7; CYCLOHEXIMIDE; CYCLOPHILIN D; FLAGELLIN; PROTEIN BAK; PROTEIN BAX; PROTEIN BNIP3; TETRAMETHYLRHODAMINE METHYL ESTER; APOPTOSIS REGULATORY PROTEIN; BACTERIAL PROTEIN; BNIP3 PROTEIN, MOUSE; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; BACTERIAL LOAD; BONE MARROW DERIVED MACROPHAGE; CELL CULTURE; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; COLONY FORMING UNIT; EMBRYONIC STEM CELL; GENE DELETION; IMMUNOBLOTTING; LEGIONELLA PNEUMOPHILA; LUNG INFECTION; MACROPHAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN SYNTHESIS INHIBITION; PYROPTOSIS; SOUTHERN BLOTTING; ANIMAL; APOPTOSIS; FEMALE; GENETICS; HOST PATHOGEN INTERACTION; LEGIONNAIRE DISEASE; METABOLISM; MICROBIOLOGY; MITOCHONDRION; PHYSIOLOGY;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BACTERIAL PROTEINS; CELL DEATH; CELL SURVIVAL; FEMALE; FLAGELLIN; GENE DELETION; HOST-PATHOGEN INTERACTIONS; LEGIONELLA PNEUMOPHILA; LEGIONNAIRES' DISEASE; MACROPHAGES; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; VIRULENCE FACTORS;

EID: 85014687876     PISSN: None     EISSN: 22352988     Source Type: Journal    
DOI: 10.3389/fcimb.2017.00035     Document Type: Article

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