-
1
-
-
77952313777
-
Differentiation of effector CD4 T cell populations
-
Zhu, J., H. Yamane, and W. E. Paul. 2010. Differentiation of effector CD4 T cell populations. Annu. Rev. Immunol. 28: 445-489.
-
(2010)
Annu. Rev. Immunol.
, vol.28
, pp. 445-489
-
-
Zhu, J.1
Yamane, H.2
Paul, W.E.3
-
2
-
-
74549179138
-
Interferons direct Th2 cell reprogramming to generate a stable GATA-3+T-bet+ cell subset with combined Th2 and Th1 cell functions
-
Hegazy, A. N., M. Peine, C. Helmstetter, I. Panse, A. Fröhlich, A. Bergthaler, L. Flatz, D. D. Pinschewer, A. Radbruch, and M. Löhning. 2010. Interferons direct Th2 cell reprogramming to generate a stable GATA-3+T-bet+ cell subset with combined Th2 and Th1 cell functions. Immunity 32: 116-128.
-
(2010)
Immunity
, vol.32
, pp. 116-128
-
-
Hegazy, A.N.1
Peine, M.2
Helmstetter, C.3
Panse, I.4
Fröhlich, A.5
Bergthaler, A.6
Flatz, L.7
Pinschewer, D.D.8
Radbruch, A.9
Löhning, M.10
-
3
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Lee, Y. K., H. Turner, C. L. Maynard, J. R. Oliver, D. Chen, C. O. Elson, and C. T. Weaver. 2009. Late developmental plasticity in the T helper 17 lineage. Immunity 30: 92-107.
-
(2009)
Immunity
, vol.30
, pp. 92-107
-
-
Lee, Y.K.1
Turner, H.2
Maynard, C.L.3
Oliver, J.R.4
Chen, D.5
Elson, C.O.6
Weaver, C.T.7
-
4
-
-
33748174156
-
T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype
-
Mathur, A. N., H. C. Chang, D. G. Zisoulis, R. Kapur, M. L. Belladonna, G. S. Kansas, and M. H. Kaplan. 2006. T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype. Blood 108: 1595-1601.
-
(2006)
Blood
, vol.108
, pp. 1595-1601
-
-
Mathur, A.N.1
Chang, H.C.2
Zisoulis, D.G.3
Kapur, R.4
Belladonna, M.L.5
Kansas, G.S.6
Kaplan, M.H.7
-
5
-
-
77953238901
-
Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage
-
Mukasa, R., A. Balasubramani, Y. K. Lee, S. K. Whitley, B. T. Weaver, Y. Shibata, G. E. Crawford, R. D. Hatton, and C. T. Weaver. 2010. Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage. Immunity 32: 616-627.
-
(2010)
Immunity
, vol.32
, pp. 616-627
-
-
Mukasa, R.1
Balasubramani, A.2
Lee, Y.K.3
Whitley, S.K.4
Weaver, B.T.5
Shibata, Y.6
Crawford, G.E.7
Hatton, R.D.8
Weaver, C.T.9
-
6
-
-
58749105841
-
IL-23 promotes maintenance but not commitment to the Th17 lineage
-
Stritesky, G. L., N. Yeh, and M. H. Kaplan. 2008. IL-23 promotes maintenance but not commitment to the Th17 lineage. J. Immunol. 181: 5948-5955.
-
(2008)
J. Immunol.
, vol.181
, pp. 5948-5955
-
-
Stritesky, G.L.1
Yeh, N.2
Kaplan, M.H.3
-
7
-
-
79951677394
-
Fate mapping of IL-17-producing T cells in inflammatory responses
-
Hirota, K., J. H. Duarte, M. Veldhoen, E. Hornsby, Y. Li, D. J. Cua, H. Ahlfors, C. Wilhelm, M. Tolaini, U. Menzel, et al. 2011. Fate mapping of IL-17-producing T cells in inflammatory responses. Nat. Immunol. 12: 255-263.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 255-263
-
-
Hirota, K.1
Duarte, J.H.2
Veldhoen, M.3
Hornsby, E.4
Li, Y.5
Cua, D.J.6
Ahlfors, H.7
Wilhelm, C.8
Tolaini, M.9
Menzel, U.10
-
8
-
-
58149214356
-
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
-
Wei, G., L. Wei, J. Zhu, C. Zang, J. Hu-Li, Z. Yao, K. Cui, Y. Kanno, T. Y. Roh, W. T. Watford, et al. 2009. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 30: 155-167.
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
Wei, L.2
Zhu, J.3
Zang, C.4
Hu-Li, J.5
Yao, Z.6
Cui, K.7
Kanno, Y.8
Roh, T.Y.9
Watford, W.T.10
-
9
-
-
84928584195
-
The development and in vivo function of T helper 9 cells
-
Kaplan, M. H., M. M. Hufford, and M. R. Olson. 2015. The development and in vivo function of T helper 9 cells. Nat. Rev. Immunol. 15: 295-307.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 295-307
-
-
Kaplan, M.H.1
Hufford, M.M.2
Olson, M.R.3
-
10
-
-
84988915863
-
The ETS family transcription factors Etv5 and PU. 1 function in parallel to promote Th9 cell development
-
Koh, B., M. M. Hufford, D. Pham, M. R. Olson, T. Wu, R. Jabeen, X. Sun, and M. H. Kaplan. 2016. The ETS family transcription factors Etv5 and PU.1 function in parallel to promote Th9 cell development. J. Immunol. 197: 2465-2472.
-
(2016)
J. Immunol.
, vol.197
, pp. 2465-2472
-
-
Koh, B.1
Hufford, M.M.2
Pham, D.3
Olson, M.R.4
Wu, T.5
Jabeen, R.6
Sun, X.7
Kaplan, M.H.8
-
11
-
-
73349109145
-
Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes
-
Jäger, A., V. Dardalhon, R. A. Sobel, E. Bettelli, and V. K. Kuchroo. 2009. Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J. Immunol. 183: 7169-7177.
-
(2009)
J. Immunol.
, vol.183
, pp. 7169-7177
-
-
Jäger, A.1
Dardalhon, V.2
Sobel, R.A.3
Bettelli, E.4
Kuchroo, V.K.5
-
12
-
-
78650666947
-
Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site
-
Tan, C., M. K. Aziz, J. D. Lovaas, B. P. Vistica, G. Shi, E. F. Wawrousek, and I. Gery. 2010. Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site. J. Immunol. 185: 6795-6801.
-
(2010)
J. Immunol.
, vol.185
, pp. 6795-6801
-
-
Tan, C.1
Aziz, M.K.2
Lovaas, J.D.3
Vistica, B.P.4
Shi, G.5
Wawrousek, E.F.6
Gery, I.7
-
13
-
-
84885831692
-
Th9 cells drive host immunity against gastrointestinal worm infection
-
Licona-Limón, P., J. Henao-Mejia, A. U. Temann, N. Gagliani, I. Licona-Limón, H. Ishigame, L. Hao, D. R. Herbert, and R. A. Flavell. 2013. Th9 cells drive host immunity against gastrointestinal worm infection. Immunity 39: 744-757.
-
(2013)
Immunity
, vol.39
, pp. 744-757
-
-
Licona-Limón, P.1
Henao-Mejia, J.2
Temann, A.U.3
Gagliani, N.4
Licona-Limón, I.5
Ishigame, H.6
Hao, L.7
Herbert, D.R.8
Flavell, R.A.9
-
14
-
-
84938537213
-
TH9 cells are required for tissue mast cell accumulation during allergic inflammation
-
Sehra, S., W. Yao, E. T. Nguyen, N. L. Glosson-Byers, N. Akhtar, B. Zhou, and M. H. Kaplan. 2015. TH9 cells are required for tissue mast cell accumulation during allergic inflammation. J. Allergy Clin. Immunol. 136: 433-440.e1.
-
(2015)
J. Allergy Clin. Immunol.
, vol.136
, pp. 433e1-440e1
-
-
Sehra, S.1
Yao, W.2
Nguyen, E.T.3
Glosson-Byers, N.L.4
Akhtar, N.5
Zhou, B.6
Kaplan, M.H.7
-
15
-
-
77955902281
-
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells
-
Staudt, V., E. Bothur, M. Klein, K. Lingnau, S. Reuter, N. Grebe, B. Gerlitzki, M. Hoffmann, A. Ulges, C. Taube, et al. 2010. Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity 33: 192-202.
-
(2010)
Immunity
, vol.33
, pp. 192-202
-
-
Staudt, V.1
Bothur, E.2
Klein, M.3
Lingnau, K.4
Reuter, S.5
Grebe, N.6
Gerlitzki, B.7
Hoffmann, M.8
Ulges, A.9
Taube, C.10
-
16
-
-
84874241774
-
Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP
-
Yao, W., Y. Zhang, R. Jabeen, E. T. Nguyen, D. S. Wilkes, R. S. Tepper, M. H. Kaplan, and B. Zhou. 2013. Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP. Immunity 38: 360-372.
-
(2013)
Immunity
, vol.38
, pp. 360-372
-
-
Yao, W.1
Zhang, Y.2
Jabeen, R.3
Nguyen, E.T.4
Wilkes, D.S.5
Tepper, R.S.6
Kaplan, M.H.7
Zhou, B.8
-
17
-
-
84919869139
-
IL-9 is a key component of memory TH cell peanut-specific responses from children with peanut allergy
-
Brough, H. A., D. J. Cousins, A. Munteanu, Y. F. Wong, A. Sudra, K. Makinson, A. C. Stephens, M. Arno, L. Ciortuz, G. Lack, and V. Turcanu. 2014. IL-9 is a key component of memory TH cell peanut-specific responses from children with peanut allergy. J. Allergy Clin. Immunol. 134: 1329-1338.e10.
-
(2014)
J. Allergy Clin. Immunol.
, vol.134
, pp. 1329e10-1338e10
-
-
Brough, H.A.1
Cousins, D.J.2
Munteanu, A.3
Wong, Y.F.4
Sudra, A.5
Makinson, K.6
Stephens, A.C.7
Arno, M.8
Ciortuz, L.9
Lack, G.10
Turcanu, V.11
-
18
-
-
84867422699
-
Elevated antigen-driven IL-9 responses are prominent in peanut allergic humans
-
Xie, J., L. C. Lotoski, R. Chooniedass, R. C. Su, F. E. Simons, J. Liem, A. B. Becker, J. Uzonna, and K. T. HayGlass. 2012. Elevated antigen-driven IL-9 responses are prominent in peanut allergic humans. PLoS One 7: e45377.
-
(2012)
PLoS One
, vol.7
, pp. e45377
-
-
Xie, J.1
Lotoski, L.C.2
Chooniedass, R.3
Su, R.C.4
Simons, F.E.5
Liem, J.6
Becker, A.B.7
Uzonna, J.8
HayGlass, K.T.9
-
19
-
-
82555167120
-
Predisposition to the development of IL-9-secreting T cells in atopic infants
-
Yao, W., R. S. Tepper, and M. H. Kaplan. 2011. Predisposition to the development of IL-9-secreting T cells in atopic infants. J. Allergy Clin. Immunol. 128: 1357-1360.e5.
-
(2011)
J. Allergy Clin. Immunol.
, vol.128
, pp. 1357-1357e5
-
-
Yao, W.1
Tepper, R.S.2
Kaplan, M.H.3
-
20
-
-
0032412441
-
Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
-
Agarwal, S., and A. Rao. 1998. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity 9: 765-775.
-
(1998)
Immunity
, vol.9
, pp. 765-775
-
-
Agarwal, S.1
Rao, A.2
-
21
-
-
0032143821
-
Helper T cell differentiation is controlled by the cell cycle
-
Bird, J. J., D. R. Brown, A. C. Mullen, N. H. Moskowitz, M. A. Mahowald, J. R. Sider, T. F. Gajewski, C. R. Wang, and S. L. Reiner. 1998. Helper T cell differentiation is controlled by the cell cycle. Immunity 9: 229-237.
-
(1998)
Immunity
, vol.9
, pp. 229-237
-
-
Bird, J.J.1
Brown, D.R.2
Mullen, A.C.3
Moskowitz, N.H.4
Mahowald, M.A.5
Sider, J.R.6
Gajewski, T.F.7
Wang, C.R.8
Reiner, S.L.9
-
22
-
-
0029965236
-
Reversibility of T helper 1 and 2 populations is lost after long-term stimulation
-
Murphy, E., K. Shibuya, N. Hosken, P. Openshaw, V. Maino, K. Davis, K. Murphy, and A. O'Garra. 1996. Reversibility of T helper 1 and 2 populations is lost after long-term stimulation. J. Exp. Med. 183: 901-913.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 901-913
-
-
Murphy, E.1
Shibuya, K.2
Hosken, N.3
Openshaw, P.4
Maino, V.5
Davis, K.6
Murphy, K.7
O'Garra, A.8
-
23
-
-
84902653958
-
TH9 cells that express the transcription factor PU. 1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells
-
Gerlach, K., Y. Hwang, A. Nikolaev, R. Atreya, H. Dornhoff, S. Steiner, H. A. Lehr, S. Wirtz, M. Vieth, A. Waisman, et al. 2014. TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells. Nat. Immunol. 15: 676-686.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 676-686
-
-
Gerlach, K.1
Hwang, Y.2
Nikolaev, A.3
Atreya, R.4
Dornhoff, H.5
Steiner, S.6
Lehr, H.A.7
Wirtz, S.8
Vieth, M.9
Waisman, A.10
-
24
-
-
20944435271
-
Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
-
Chiarle, R.,W. J. Simmons, H. Cai, G. Dhall, A. Zamo, R. Raz, J. G. Karras, D. E. Levy, and G. Inghirami. 2005. Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target. Nat. Med. 11: 623-629.
-
(2005)
Nat. Med.
, vol.11
, pp. 623-629
-
-
Chiarle, R.1
Simmons, W.J.2
Cai, H.3
Dhall, G.4
Zamo, A.5
Raz, R.6
Karras, J.G.7
Levy, D.E.8
Inghirami, G.9
-
25
-
-
84974849329
-
STAT3 impairs STAT5 activation in the development of IL-9-secreting T cells
-
Olson, M. R., F. F. Verdan, M. M. Hufford, A. L. Dent, and M. H. Kaplan. 2016. STAT3 impairs STAT5 activation in the development of IL-9-secreting T cells. J. Immunol. 196: 3297-3304.
-
(2016)
J. Immunol.
, vol.196
, pp. 3297-3304
-
-
Olson, M.R.1
Verdan, F.F.2
Hufford, M.M.3
Dent, A.L.4
Kaplan, M.H.5
-
26
-
-
77952584843
-
The transcription factor PU. 1 is required for the development of IL-9-producing T cells and allergic inflammation
-
Chang, H. C., S. Sehra, R. Goswami, W. Yao, Q. Yu, G. L. Stritesky, R. Jabeen, C. McKinley, A. N. Ahyi, L. Han, et al. 2010. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat. Immunol. 11: 527-534.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 527-534
-
-
Chang, H.C.1
Sehra, S.2
Goswami, R.3
Yao, W.4
Yu, Q.5
Stritesky, G.L.6
Jabeen, R.7
McKinley, C.8
Ahyi, A.N.9
Han, L.10
-
27
-
-
77953957751
-
Cell type-specific regulation of IL-10 expression in inflammation and disease
-
Hedrich, C. M., and J. H. Bream. 2010. Cell type-specific regulation of IL-10 expression in inflammation and disease. Immunol. Res. 47: 185-206.
-
(2010)
Immunol. Res.
, vol.47
, pp. 185-206
-
-
Hedrich, C.M.1
Bream, J.H.2
-
28
-
-
0028077321
-
IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma
-
Schmitt, E., T. Germann, S. Goedert, P. Hoehn, C. Huels, S. Koelsch, R. Kuhn, W. Muller, N. Palm, and E. Rude. 1994. IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma. J. Immunol. 153: 3989-3996.
-
(1994)
J. Immunol.
, vol.153
, pp. 3989-3996
-
-
Schmitt, E.1
Germann, T.2
Goedert, S.3
Hoehn, P.4
Huels, C.5
Koelsch, S.6
Kuhn, R.7
Muller, W.8
Palm, N.9
Rude, E.10
-
29
-
-
84881121485
-
Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function
-
Ives, M. L., C. S. Ma, U. Palendira, A. Chan, J. Bustamante, S. Boisson-Dupuis, P. D. Arkwright, D. Engelhard, D. Averbuch, K. Magdorf, et al. 2013. Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function. J. Allergy Clin. Immunol. 132: 400-411.e9.
-
(2013)
J. Allergy Clin. Immunol.
, vol.132
, pp. 400-400e9
-
-
Ives, M.L.1
Ma, C.S.2
Palendira, U.3
Chan, A.4
Bustamante, J.5
Boisson-Dupuis, S.6
Arkwright, P.D.7
Engelhard, D.8
Averbuch, D.9
Magdorf, K.10
-
30
-
-
0030573991
-
IL-10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes
-
Wehinger, J., F. Gouilleux, B. Groner, J. Finke, R. Mertelsmann, and R. M. Weber-Nordt. 1996. IL-10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes. FEBS Lett. 394: 365-370.
-
(1996)
FEBS Lett.
, vol.394
, pp. 365-370
-
-
Wehinger, J.1
Gouilleux, F.2
Groner, B.3
Finke, J.4
Mertelsmann, R.5
Weber-Nordt, R.M.6
-
31
-
-
84868611628
-
Th9 cells promote antitumor immune responses in vivo
-
Lu, Y., S. Hong, H. Li, J. Park, B. Hong, L. Wang, Y. Zheng, Z. Liu, J. Xu, J. He, et al. 2012. Th9 cells promote antitumor immune responses in vivo. J. Clin. Invest. 122: 4160-4171.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 4160-4171
-
-
Lu, Y.1
Hong, S.2
Li, H.3
Park, J.4
Hong, B.5
Wang, L.6
Zheng, Y.7
Liu, Z.8
Xu, J.9
He, J.10
-
32
-
-
84904656835
-
The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells
-
Végran, F., H. Berger, R. Boidot, G. Mignot, M. Bruchard, M. Dosset, F. Chalmin, C. Rébé, V. Dérangère, B. Ryffel, et al. 2014. The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells. Nat. Immunol. 15: 758-766.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 758-766
-
-
Végran, F.1
Berger, H.2
Boidot, R.3
Mignot, G.4
Bruchard, M.5
Dosset, M.6
Chalmin, F.7
Rébé, C.8
Dérangère, V.9
Ryffel, B.10
-
33
-
-
58149216715
-
Th memory for interleukin-17 expression is stable in vivo
-
Lexberg, M. H., A. Taubner, A. Fö rster, I. Albrecht, A. Richter, T. Kamradt, A. Radbruch, and H. D. Chang. 2008. Th memory for interleukin-17 expression is stable in vivo. Eur. J. Immunol. 38: 2654-2664.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 2654-2664
-
-
Lexberg, M.H.1
Taubner, A.2
Fö Rster, A.3
Albrecht, I.4
Richter, A.5
Kamradt, T.6
Radbruch, A.7
Chang, H.D.8
-
34
-
-
77955658181
-
Regulation of human Th9 differentiation by type i interferons and IL-21
-
Wong, M. T., J. J. Ye, M. N. Alonso, A. Landrigan, R. K. Cheung, E. Engleman, and P. J. Utz. 2010. Regulation of human Th9 differentiation by type I interferons and IL-21. Immunol. Cell Biol. 88: 624-631.
-
(2010)
Immunol. Cell Biol.
, vol.88
, pp. 624-631
-
-
Wong, M.T.1
Ye, J.J.2
Alonso, M.N.3
Landrigan, A.4
Cheung, R.K.5
Engleman, E.6
Utz, P.J.7
-
35
-
-
84907087908
-
Th17 cells demonstrate stable cytokine production in a proallergic environment
-
Glosson-Byers, N. L., S. Sehra, G. L. Stritesky, Q. Yu, O. Awe, D. Pham, H. A. Bruns, and M. H. Kaplan. 2014. Th17 cells demonstrate stable cytokine production in a proallergic environment. J. Immunol. 193: 2631-2640.
-
(2014)
J. Immunol.
, vol.193
, pp. 2631-2640
-
-
Glosson-Byers, N.L.1
Sehra, S.2
Stritesky, G.L.3
Yu, Q.4
Awe, O.5
Pham, D.6
Bruns, H.A.7
Kaplan, M.H.8
-
36
-
-
63149142776
-
Cutting edge: An IL-17F-CreEYFP reporter mouse allows fate mapping of Th17 cells
-
Croxford, A. L., F. C. Kurschus, and A. Waisman. 2009. Cutting edge: an IL-17F-CreEYFP reporter mouse allows fate mapping of Th17 cells. J. Immunol. 182: 1237-1241.
-
(2009)
J. Immunol.
, vol.182
, pp. 1237-1241
-
-
Croxford, A.L.1
Kurschus, F.C.2
Waisman, A.3
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