Predisposition to the development of IL-9-secreting T cells in atopic infants

Journal of Allergy and Clinical Immunology

Volumn 128, Issue 6, 2011, Pages 1357-1360.e5

  Yao, Weiguo ^a   Tepper, Robert S ^a   Kaplan, Mark H ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CD3 ANTIBODY; CD45RA ANTIGEN; FOOD ALLERGEN; GAMMA INTERFERON; HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 22; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 9; INTERLEUKIN 9 RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; RETINOID RELATED ORPHAN RECEPTOR GAMMA; STAT6 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET;

ALLERGIC DISEASE; ATOPY; CAT; CD4+ T LYMPHOCYTE; CELL ISOLATION; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA POLYMORPHISM; EGG; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOSTIMULATION; LETTER; LUNG LAVAGE; LYMPHOCYTE; LYMPHOCYTE CULTURE; LYMPHOCYTE DIFFERENTIATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL;

EID: 82555167120     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.06.019     Document Type: Article

References (11)

1. R. Goswami, and M.H. Kaplan A brief history of IL-9 J Immunol 186 2011 3283 3288
2. S. Devos, F. Cormont, S. Vrtala, E. Hooghe-Peters, F. Pirson, and J. Snick Allergen-induced interleukin-9 production in vitro: correlation with atopy in human adults and comparison with interleukin-5 and interleukin-13 Clin Exp Allergy 36 2006 174 182
3. V.J. Erpenbeck, J.M. Hohlfeld, M. Discher, H. Krentel, A. Hagenberg, and A. Braun Increased expression of interleukin-9 messenger RNA after segmental allergen challenge in allergic asthmatics Chest 123 2003 370S (Pubitemid 36315414)
4. M.C. Jenmalm, J. Van Snick, F. Cormont, and B. Salman Allergen-induced Th1 and Th2 cytokine secretion in relation to specific allergen sensitization and atopic symptoms in children Clin Exp Allergy 31 2001 1528 1535 (Pubitemid 32939459)
5. R.S. Tepper, C.J. Llapur, M.H. Jones, C. Tiller, C. Coates, and R. Kimmel Expired nitric oxide and airway reactivity in infants at risk for asthma J Allergy Clin Immunol 122 2008 760 765
6. W. Yao, F.M. Barbe-Tuana, C.J. Llapur, M.H. Jones, C. Tiller, and R. Kimmel Evaluation of airway reactivity and immune characteristics as risk factors for wheezing early in life J Allergy Clin Immunol 126 2010 483.e1-488.e1
7. H.C. Chang, S. Sehra, R. Goswami, W. Yao, Q. Yu, and G.L. Stritesky The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation Nat Immunol 11 2010 527 534
8. V. Dardalhon, A. Awasthi, H. Kwon, G. Galileos, W. Gao, and R.A. Sobel IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells Nat Immunol 9 2008 1347 1355
9. M. Veldhoen, C. Uyttenhove, J. van Snick, H. Helmby, A. Westendorf, and J. Buer Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset Nat Immunol 9 2008 1341 1346
10. R.S. Tepper, C.J. Llapur, M.H. Jones, C. Tiller, C. Coates, and R. Kimmel Expired nitric oxide and airway reactivity in infants at risk for asthma J Allergy Clin Immunol 122 2008 760 765
11. W. Yao, F.M. Barbe-Tuana, C.J. Llapur, M.H. Jones, C. Tiller, and R. Kimmel Evaluation of airway reactivity and immune characteristics as risk factors for wheezing early in life J Allergy Clin Immunol 126 2010 483.e1-488.e1