Impact of Bariatric Surgery on Metabolic and Gut Microbiota Profile: a Systematic Review and Meta-analysis

Obesity Surgery

Volumn 27, Issue 5, 2017, Pages 1345-1357

  Magouliotis, Dimitrios E ^a   Tasiopoulou, Vasiliki S ^b   Sioka, Eleni ^a   Chatedaki, Christina ^a   Zacharoulis, Dimitrios ^a  

^a UNIVERSITY HOSPITAL OF LARISSA   (Greece)

^b UNIVERSITY OF THESSALY   (Greece)

Author keywords

AGB; Bariatric surgery; Gut microbiota; Metabolites; RYGB; SG

Indexed keywords

BRANCHED CHAIN AMINO ACID; CHOLESTEROL; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 2; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN; PEPTIDE YY; TRIACYLGLYCEROL; TRIMETHYLAMINE OXIDE;

AMINO ACID BLOOD LEVEL; BARIATRIC SURGERY; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; DIABETES MELLITUS; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HOMEOSTASIS MODEL ASSESSMENT; HORMONE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INTESTINE FLORA; LIPOPROTEIN BLOOD LEVEL; META ANALYSIS; METABOLISM; OBESITY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REMISSION; REVIEW; SYSTEMATIC REVIEW; THERAPY EFFECT; TRIACYLGLYCEROL BLOOD LEVEL; ADULT; ANALYSIS; BLOOD; FEMALE; MALE; MIDDLE AGED; PHYSIOLOGY; YOUNG ADULT;

ADULT; AMINO ACIDS, BRANCHED-CHAIN; BARIATRIC SURGERY; BLOOD GLUCOSE; FEMALE; GASTROINTESTINAL MICROBIOME; GLUCAGON-LIKE PEPTIDE 1; HUMANS; INSULIN; MALE; MIDDLE AGED; OBESITY; YOUNG ADULT;

EID: 85014514533     PISSN: 09608923     EISSN: 17080428     Source Type: Journal    
DOI: 10.1007/s11695-017-2595-8     Document Type: Review

References (52)

1. Flegal KM, Carroll MD, Kit BK, et al. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999–2010. J Am Med Assoc. 2012;307(5):491–7.
2. Sjφstrφm L, Peltonen M, Jacobson P, et al. Association of bariatric surgery with long-term remission of type 2 diabetes and with microvascular and macrovascular complications. JAMA. American Medical Association. 2014;311:2297–304. doi:10.1001/jama.2014.5988.
3. Sjφstrφm L, Peltonen M, Jacobson P, et al. Bariatric surgery and long-term cardiovascular events. JAMA American Medical Association. 2012;307:56–65.
4. Stewart B, WCP editors. IA for R on CW. World cancer report 2014. 2014; Available: http://www.thehealthwell.info/node/725845
5. Colquit JL, Picot J, Loveman E, et al. Surgery for obesity. Cochrane Database Syst Rev. 2009;(2):CD003641.
6. Kaska L, Sledzinski T, Chomiczewska A, et al. Improved glucose metabolism following bariatric surgery is associated with increased circulating bile acid concentrations and remodeling of the gut microbiome. World J Gastroenterol. 2016;22(39):8698–719.
7. Quercia I, Dutia R, Kotler DP, et al. Gastrointestinal changes after bariatric surgery. Diabetes Metab. 2014;40:87–94. doi:10.1016/j.diabet.2013.11.003.
8. Ley RE, Turnbaugh PJ, Klein S, et al. Microbial ecology: human gut microbes associated with obesity. Nature. 2006;444:1022–3.
9. Turnbaugh PJ, Hamady M, Yatsunenko T, et al. A core gut microbiome in obese and lean twins. Nature. 2009;457:480–4.
10. Flint HJ. Obesity and the gut microbiota. J Clin Gastroenterol. 2011;45(Suppl):S128–32.
11. Li JV, Ashrafian H, Bueter M, et al. Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk. Gut. 2011;60(9):1214–23.
12. Ashrafian H, Li JV, Spagou K, et al. Bariatric surgery modulates circulating and cardiac metabolites. J Proteome Res. 2014;13:570–80. doi:10.1021/pr400748f.
13. Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6:e1000100.
14. Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions version 5.1.0 [updated March 2011]. The Cochrane Collaboration. 2011 Available from www.cochrane-handbook.org
15. Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25:603–5.
16. H.J. GSE. (2011) Cochrane handbook for systematic reviews of interventions version 5.1.0 [updated March 2011]
17. Egger M, Smith DG, Schneider M, et al. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629–34.
18. Alamuddin N, Vetter ML, Ahima RS, et al. Changes in fasting and prandial gut and adiposity hormones following vertical sleeve gastrectomy or Roux-en-Y-gastric bypass: an 18-month prospective study. Obes Surg. 2016; doi:10.1007/s11695-016-2505-5.
19. Arora T, Velagapudi V, Pournaras DJ, et al. Roux-en-Y gastric bypass surgery induces early plasma metabolomic and lipidomic alterations in humans associated with diabetes remission. PLoS One. 2015;10(5):e0126401. doi:10.1371/journal.pone.0126401.
20. Federico A, Dallio M, Tolone S, et al. Gastrointestinal hormones, intestinal microbiota and metabolic homeostasis in obese patients: effect of bariatric surgery. in vivo. 2016;30:321–30.
21. Furet JP, Kong LC, Tap J, et al. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers. Diabetes. 2010;59(12):3049–57. doi:10.2337/db10-0253.
22. Graessler J, Qin Y, Zhong H, et al. Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters. The Pharmacogenomics Journal. 2013;13:514–22. doi:10.1038/tpj.2012.43.
23. Gralka E, Luchinat C, Tenori L, et al. Metabolomic fingerprint of severe obesity is dynamically affected by bariatric surgery in a procedure-dependent manner. Am J Clin Nutr. 2015; doi:10.3945/ajcn.115.110536.
24. Ishida RK, Faintuch J, Ribeiro AS, et al. Asymptomatic gastric bacterial overgrowth after bariatric surgery: are long-term metabolic consequences possible? Obes Surg. 2014;24:1856–61. doi:10.1007/s11695-014-1277-z.
25. Jüllig M, Yip S, Xu A, et al. Lower fetuin-A, retinol binding protein 4 and several metabolites after gastric bypass compared to sleeve gastrectomy in patients with type 2 diabetes. PLoS One. 2014;9(5):e96489. doi:10.1371/journal.pone.0096489.
26. Karamanakos SN, Vagenas K, Kalfarentzos F, et al. Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a prospective, double blind study. Ann Surg. 2008;247:401–7.
27. Kong LC, Tap J, Aron-Wisnewsky J, et al. Gut microbiota after gastric bypass in human obesity: increased richness and associations of bacterial genera with adipose tissue genes. Am J Clin Nutr. 2013;98:16–24.
28. Lips MA, Van Klinken JB, van Harmelen V, et al. Roux-en-Y gastric bypass surgery, but not calorie restriction, reduces plasma branched-chain amino acids in obese women independent of weight loss or the presence of type 2 diabetes. Diabetes Care. 2014;37:3150–6. doi:10.2337/dc14-0195.
29. 1H NMR-based metabolomics. OMICS A J Integ Biol 2016;20(7). doi:10.1089/omi.2016.0061
30. Magkos F, Bradley D, Schweitzer GG, et al. Effect of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on branched-chain amino acid metabolism. Diabetes 2013;62. DOI: 10.2337/db13-0185.
31. Murphy R, Tsai P, Jüllig M, et al. Differential changes in gut microbiota after gastric bypass and sleeve gastrectomy bariatric surgery vary according to diabetes remission. Obes Surg. 2016; doi:10.1007/s11695-016-2399-2.
32. Narath SH, Mautner SI, Svehlikova E, et al. An untargeted metabolomics approach to characterize short-term and long-term metabolic changes after bariatric surgery. PLoS One. 2016;11(9):e0161425. doi:10.1371/journal.pone.0161425.
33. Palleja A, Kashani A, Allin KH, et al. Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota. Genome Medicine. 2016;8:67. doi:10.1186/s13073-016-0312-1.
34. Papamargaritis D, le Roux CW, Sioka E, et al. Changes in gut hormone profile and glucose homeostasis after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis. 2013;9:192–201.
35. Patrone V, Vajana E, Minuti A, et al. Postoperative changes in fecal bacterial communities and fermentation products in obese patients undergoing bilio-intestinal bypass. Front Microbiol. 2016;7:200. doi:10.3389/fmicb.2016.00200.
36. Peterli R, Wφlnerhanssen B, Peters T, et al. Improvement in glucose metabolism after bariatric surgery: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: a prospective randomized trial. Ann Surg. 2009 Aug;250(2):234–41. doi:10.1097/SLA.0b013e3181ae32e3.
37. Tremaroli V, Karlsson F, Werling M, et al. Roux-en-Y gastric bypass and vertical banded gastroplasty induce long-term changes on the human gut microbiome contributing to fat mass regulation. Cell Metab. 2015;22:228–38. doi:10.1016/j.cmet.2015.07.009.
38. Trøseid M, Hov JR, Nestvold TK, et al. Major increase in microbiota-dependent proatherogenic metabolite TMAO one year after bariatric surgery. METABOLIC SYNDROME AND RELATED DISORDERS Volume 14, Number 4, 2016 DOI: 10.1089/met.2015.0120
39. Valderas JP, Irribarra V, Rubio L, et al. Effects of sleeve gastrectomy and medical treatment for obesity on glucagon-like peptide 1 levels and glucose homeostasis in non-diabetic subjects. Obes Surg. 2011;21:902–9. doi:10.1007/s11695-011-0375-4.
40. Ley RE, Bäckhed F, Turnbaugh P, et al. Obesity alters gut microbial ecology. Proc Natl Acad Sci U S A. 2005;102:11070–5. doi:10.1073/pnas.0504978102.
41. Turnbaugh PJ, Bδckhed F, Fulton L, et al. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe. 2008;3:213–23. doi:10.1016/j.chom.2008.02.015.
42. Buchwald H, Oien DM. Metabolic/bariatric surgery worldwide 2011. Obes Surg. 2013;23:427–36.
43. Horowitz M, Cook DJ, Collins PJ, et al. Measurement of gastric emptying after gastric bypass surgery using radionuclides. Br J Surg. 1982;69:655–7.
44. Melissas J, Koukouraki S, Askoxylakis J, et al. Sleeve gastrectomy: a restrictive procedure? Obes Surg. 2007;17:57–62.
45. Thaler JP, Cummings DE. Minireview: Hormonal and metabolic mechanisms of diabetes remission after gastrointestinal surgery. Endocrinology. 2009;150:2518–25.
46. Rubino F, Forgione A, Cummings DE, et al. The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes. Ann Surg. 2006;244:741–9.
47. Newgard CB, An J, Bain JR, et al. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab. 2009;9:311–26.
48. Adeva MM, Calviρo J, Souto G, et al. Insulin resistance and the metabolism of branched-chain amino acids in humans. Amino Acids. 2012;43:171–81.
49. Saha AK, Xu XJ, Balon TW, et al. Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation? Cell Cycle. 2011;10:3447–51.
50. Saha AK, Xu XJ, Lawson E, et al. Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle. Diabetes. 2010;59:2426–34.
51. Newgard CB. Interplay between lipids and branched-chain amino acids in development of insulin resistance. Cell Metab. 2012;15:606–14.
52. Magouliotis DE, Tasiopoulou VS, Sioka E, et al. Robotic versus laparoscopic sleeve gastrectomy for morbid obesity: a systematic review and meta-analysis. Obes Surg. 2017;27:245. doi:10.1007/s11695-016-2444-1.