-
1
-
-
0018896297
-
Mechanisms of insulin resistance in human obesity: Evidence for receptor and postreceptor defects
-
Kolterman OG, Insel J, Saekow M, Olefsky JM. Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects. J Clin Invest 1980;65:1272-1284
-
(1980)
J Clin Invest
, vol.65
, pp. 1272-1284
-
-
Kolterman, O.G.1
Insel, J.2
Saekow, M.3
Olefsky, J.M.4
-
2
-
-
0020422279
-
Insulin resistance in humans
-
Olefsky JM. Insulin resistance in humans. Gastroenterology 1982;83:1313- 1318
-
(1982)
Gastroenterology
, vol.83
, pp. 1313-1318
-
-
Olefsky, J.M.1
-
3
-
-
33645474277
-
Insulin resistance - A common link between type 2 diabetes and cardiovascular disease
-
Lebovitz HE. Insulin resistance - a common link between type 2 diabetes and cardiovascular disease. Diabetes Obes Metab 2006;8:237-249
-
(2006)
Diabetes Obes Metab
, vol.8
, pp. 237-249
-
-
Lebovitz, H.E.1
-
4
-
-
84857861919
-
Mechanisms for insulin resistance: Common threads and missing links
-
Samuel VT, Shulman GI. Mechanisms for insulin resistance: common threads and missing links. Cell 2012;148:852-871
-
(2012)
Cell
, vol.148
, pp. 852-871
-
-
Samuel, V.T.1
Shulman, G.I.2
-
5
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003;112:1796-1808
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
6
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI. Cellular mechanisms of insulin resistance. J Clin Invest 2000; 106:171-176
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
7
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley DE, He J, Menshikova EV, Ritov VB. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002;51:2944-2950
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
8
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004;306:457-461
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
-
9
-
-
63449111894
-
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
-
Newgard CB, An J, Bain JR, et al. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab 2009;9:311-326
-
(2009)
Cell Metab
, vol.9
, pp. 311-326
-
-
Newgard, C.B.1
An, J.2
Bain, J.R.3
-
10
-
-
84862757927
-
Insulin resistance and the metabolism of branched-chain amino acids in humans
-
Adeva MM, Calviño J, Souto G, Donapetry C. Insulin resistance and the metabolism of branched-chain amino acids in humans. Amino Acids 2012; 43:171-181
-
(2012)
Amino Acids
, vol.43
, pp. 171-181
-
-
Adeva, M.M.1
Calviño, J.2
Souto, G.3
Donapetry, C.4
-
11
-
-
84860439210
-
Interplay between lipids and branched-chain amino acids in development of insulin resistance
-
Newgard CB. Interplay between lipids and branched-chain amino acids in development of insulin resistance. Cell Metab 2012;15:606-614
-
(2012)
Cell Metab
, vol.15
, pp. 606-614
-
-
Newgard, C.B.1
-
12
-
-
79953737332
-
Metabolite profiles and the risk of developing diabetes
-
Wang TJ, Larson MG, Vasan RS, et al. Metabolite profiles and the risk of developing diabetes. Nat Med 2011;17:448-453
-
(2011)
Nat Med
, vol.17
, pp. 448-453
-
-
Wang, T.J.1
Larson, M.G.2
Vasan, R.S.3
-
13
-
-
84856728068
-
Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss
-
Shah SH, Crosslin DR, Haynes CS, et al. Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss. Diabetologia 2012;55:321-330
-
(2012)
Diabetologia
, vol.55
, pp. 321-330
-
-
Shah, S.H.1
Crosslin, D.R.2
Haynes, C.S.3
-
14
-
-
80055115885
-
Insulin resistance due to nutrient excess: Is it a consequence of AMPK downregulation?
-
Saha AK, Xu XJ, Balon TW, Brandon A, Kraegen EW, Ruderman NB. Insulin resistance due to nutrient excess: is it a consequence of AMPK downregulation? Cell Cycle 2011;10:3447-3451
-
(2011)
Cell Cycle
, vol.10
, pp. 3447-3451
-
-
Saha, A.K.1
Xu, X.J.2
Balon, T.W.3
Brandon, A.4
Kraegen, E.W.5
Ruderman, N.B.6
-
15
-
-
77957567397
-
Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle
-
Saha AK, Xu XJ, Lawson E, et al. Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle. Diabetes 2010;59:2426-2434
-
(2010)
Diabetes
, vol.59
, pp. 2426-2434
-
-
Saha, A.K.1
Xu, X.J.2
Lawson, E.3
-
16
-
-
0035851205
-
Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells
-
Tremblay F, Marette A. Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells. J Biol Chem 2001;276:38052-38060
-
(2001)
J Biol Chem
, vol.276
, pp. 38052-38060
-
-
Tremblay, F.1
Marette, A.2
-
17
-
-
34249679233
-
The Mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man
-
Krebs M, Brunmair B, Brehm A, et al. The Mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man. Diabetes 2007;56:1600-1607
-
(2007)
Diabetes
, vol.56
, pp. 1600-1607
-
-
Krebs, M.1
Brunmair, B.2
Brehm, A.3
-
18
-
-
0036313574
-
Mechanism of amino acid-induced skeletal muscle insulin resistance in humans
-
Krebs M, Krssak M, Bernroider E, et al. Mechanism of amino acid-induced skeletal muscle insulin resistance in humans. Diabetes 2002;51:599-605
-
(2002)
Diabetes
, vol.51
, pp. 599-605
-
-
Krebs, M.1
Krssak, M.2
Bernroider, E.3
-
19
-
-
24144446404
-
Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability
-
Tremblay F, Krebs M, Dombrowski L, et al. Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability. Diabetes 2005;54:2674-2684
-
(2005)
Diabetes
, vol.54
, pp. 2674-2684
-
-
Tremblay, F.1
Krebs, M.2
Dombrowski, L.3
-
20
-
-
84866639915
-
Effects of bariatric surgery on glucose homeostasis and type 2 diabetes
-
Bradley D, Magkos F, Klein S. Effects of bariatric surgery on glucose homeostasis and type 2 diabetes. Gastroenterology 2012;143:897-912
-
(2012)
Gastroenterology
, vol.143
, pp. 897-912
-
-
Bradley, D.1
Magkos, F.2
Klein, S.3
-
21
-
-
79955387227
-
Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss
-
Laferrère B, Reilly D, Arias S, et al. Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss. Sci Transl Med 2011;3:re2
-
(2011)
Sci Transl Med
, vol.3
-
-
Laferrère, B.1
Reilly, D.2
Arias, S.3
-
22
-
-
84870542506
-
Gastric bypass and banding equally improve insulin sensitivity and b cell function
-
Bradley D, Conte C, Mittendorfer B, et al. Gastric bypass and banding equally improve insulin sensitivity and b cell function. J Clin Invest 2012; 122:4667-4674
-
(2012)
J Clin Invest
, vol.122
, pp. 4667-4674
-
-
Bradley, D.1
Conte, C.2
Mittendorfer, B.3
-
23
-
-
80052718470
-
Reproducibility of glucose, fatty acid and VLDL kinetics and multi-organ insulin sensitivity in obese subjects with non-alcoholic fatty liver disease
-
Magkos F, Fabbrini E, Korenblat K, Okunade AL, Patterson BW, Klein S. Reproducibility of glucose, fatty acid and VLDL kinetics and multi-organ insulin sensitivity in obese subjects with non-alcoholic fatty liver disease. Int J Obes (Lond) 2011;35:1233-1240
-
(2011)
Int J Obes (Lond)
, vol.35
, pp. 1233-1240
-
-
Magkos, F.1
Fabbrini, E.2
Korenblat, K.3
Okunade, A.L.4
Patterson, B.W.5
Klein, S.6
-
24
-
-
0032560521
-
Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway
-
Scott PH, Brunn GJ, Kohn AD, Roth RA, Lawrence JC Jr. Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway. Proc Natl Acad Sci USA 1998;95:7772-7777
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7772-7777
-
-
Scott, P.H.1
Brunn, G.J.2
Kohn, A.D.3
Roth, R.A.4
Lawrence Jr., J.C.5
-
25
-
-
0021333959
-
Insulindependent metabolism of branched-chain amino acids in obesity
-
Forlani G, Vannini P, Marchesini G, Zoli M, Ciavarella A, Pisi E. Insulindependent metabolism of branched-chain amino acids in obesity. Metabolism 1984;33:147-150
-
(1984)
Metabolism
, vol.33
, pp. 147-150
-
-
Forlani, G.1
Vannini, P.2
Marchesini, G.3
Zoli, M.4
Ciavarella, A.5
Pisi, E.6
|