An endoplasmic reticulum-engineered yeast platform for overproduction of triterpenoids

Metabolic Engineering

Volumn 40, Issue , 2017, Pages 165-175

  Arendt, Philipp ^a,b,c   Miettinen, Karel ^a,b   Pollier, Jacob ^a,b   De Rycke, Riet ^a,b   Callewaert, Nico ^a,c   Goossens, Alain ^a,b  

^a GHENT UNIVERSITY   (Belgium)

^b Belgium   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Combinatorial biosynthesis; Cytochrome P450; Metabolic engineering; Saponins; Terpenoids

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CELL MEMBRANES; ENZYMES; LIPIDS; METABOLISM; METABOLITES; PHOSPHATASES; PRODUCTION PLATFORMS; YEAST;

COMBINATORIAL BIOSYNTHESIS; CYTOCHROME P450; ENDOPLASMIC RETICULUM; HETEROLOGOUS PRODUCTION; PATHWAY ENGINEERINGS; PLANT-DERIVED PRODUCTS; SAPONINS; TERPENOIDS;

METABOLIC ENGINEERING;

24 CARBOXY BETA AMYRIN; ALPHA AMYRIN; ARTEMISINIC ACID; BETA AMYRIN; BETA CAROTENE; BETULIC ACID; MEDICAGENIC 28 O GLUCOSIDE; MEDICAGENIC ACID; PHOSPHATIDATE PHOSPHATASE; PHOSPHATIDATE PHOSPHATASE 1; SESQUITERPENOID; THALIANOL; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; SACCHAROMYCES CEREVISIAE PROTEIN; SAPONIN; TRITERPENE;

ARTICLE; BIOENGINEERING; CELL PROLIFERATION; CELL VACUOLE; CRISPR CAS SYSTEM; ENDOPLASMIC RETICULUM; FRAMESHIFT MUTATION; GLYCOSYLATION; HETEROLOGOUS EXPRESSION; HYDROPHOBICITY; INTRACELLULAR MEMBRANE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SACCHAROMYCES CEREVISIAE; BIOSYNTHESIS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENE EDITING; GENETIC ENHANCEMENT; GENETICS; ISOLATION AND PURIFICATION; METABOLIC ENGINEERING; METABOLISM; PHYSIOLOGY; PROCEDURES; UPREGULATION;

BIOSYNTHETIC PATHWAYS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; ENDOPLASMIC RETICULUM; GENE EDITING; GENETIC ENHANCEMENT; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; PHOSPHATIDATE PHOSPHATASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SAPONINS; TRITERPENES; UP-REGULATION;

EID: 85014353157     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2017.02.007     Document Type: Article

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