Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum

Microbial Cell Factories

Volumn 15, Issue 1, 2016, Pages

  de Ruijter, Jorg C ^a   Koskela, Essi V ^a   Frey, Alexander D ^a  

^a AALTO UNIVERSITY   (Finland)

Author keywords

Antibody; Chaperones; Endoplasmic reticulum; Heterologous protein production; Protein folding

Indexed keywords

IMMUNOGLOBULIN G; ANTIBODY; PEPTIDYLPROLYL ISOMERASE; SACCHAROMYCES CEREVISIAE PROTEIN;

ANTIBODY PRODUCTION; ANTIBODY STRUCTURE; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; CPR5 GENE; ENDOPLASMIC RETICULUM; ERO1 GENE; FUNGAL STRAIN; GENE; GENE DELETION; GENE INACTIVATION; GENE OVEREXPRESSION; HIGH THROUGHPUT SCREENING; KAR2 GENE; LHS1 GENE; MOLECULAR CLONING; NONHUMAN; OPI1 GENE; PDI1 GENE; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; SECRETORY CELL; SIL1 GENE; CHEMISTRY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PLASMID; PROMOTER REGION; TEMPERATURE;

ANTIBODIES; ENDOPLASMIC RETICULUM; PEPTIDYLPROLYL ISOMERASE; PLASMIDS; PROMOTER REGIONS, GENETIC; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TEMPERATURE;

EID: 84969508597     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-016-0488-5     Document Type: Article

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