The Acinetobacter outer membrane contains multiple specific channels for carbapenem β-lactams as revealed by kinetic characterization analyses of imipenem permeation into Acinetobacter baylyi cells

Antimicrobial Agents and Chemotherapy

Volumn 61, Issue 3, 2017, Pages

  Morán Barrio, Jorgelina ^a   Cameranesi, María M ^a   Relling, Verónica ^a   Limansky, Adriana S ^a   Brambilla, Luciano ^a   Viale, Alejandro M ^a  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

Author keywords

Acinetobacter; Antibiotic resistance; Basic amino acid channels; Carbapenem outer membrane channels; Carbapenem resistance; Gram negative bacteria; Outer membrane proteins

Indexed keywords

AMINO ACID; ARGININE; BACTERIAL PROTEIN; ERTAPENEM; IMIPENEM; MEROPENEM; OUTER MEMBRANE PROTEIN; PROTEIN CARO; PROTEIN OPRD; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BETA LACTAM; PORIN; THIENAMYCIN DERIVATIVE;

ACINETOBACTER BAUMANNII; ACINETOBACTER BAYLYI; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL OUTER MEMBRANE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING SITE; DRUG UPTAKE; GENE DELETION; HYDROLYSIS; KINETICS; NONHUMAN; PRIORITY JOURNAL; ACINETOBACTER; CELL MEMBRANE; CHEMISTRY; DEFICIENCY; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR EVOLUTION; TRANSPORT AT THE CELLULAR LEVEL;

ACINETOBACTER; ACINETOBACTER BAUMANNII; AMINO ACIDS, BASIC; ANTI-BACTERIAL AGENTS; BACTERIAL OUTER MEMBRANE PROTEINS; BETA-LACTAMS; BIOLOGICAL TRANSPORT; CELL MEMBRANE; EVOLUTION, MOLECULAR; GENE DELETION; GENE EXPRESSION; IMIPENEM; KINETICS; PORINS; THIENAMYCINS;

EID: 85014270664     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01737-16     Document Type: Article

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