Loss of the OprD homologue protein in Acinetobacter baumannii: Impact on carbapenem susceptibility

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 1, 2013, Pages 677-

  Smani, Younes ^a   Pachón, Jerónimo ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

IMIPENEM; MEROPENEM; OUTER MEMBRANE PROTEIN; PROTEIN OPRD; TICARCILLIN; UNCLASSIFIED DRUG;

ACINETOBACTER BAUMANNII; ALLELE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIAL STRAIN; BROTH DILUTION; DOWN REGULATION; ESCHERICHIA COLI; GENE DISRUPTION; LETTER; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; BACTERIAL OUTER MEMBRANE PROTEINS; BETA-LACTAM RESISTANCE; CARBAPENEMS; CELL MEMBRANE PERMEABILITY; GENE KNOCKOUT TECHNIQUES; MICROBIAL SENSITIVITY TESTS; PORINS;

EID: 84872043562     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01277-12     Document Type: Letter

References (5)

1. Catel-Ferreira M, Nehme R, Molle V, Aranda J, Bouffartigues E, Chevalier S, Bou G, Jouenne T, De E. 2012. Deciphering the function of the outer membrane protein OprD homologue of Acinetobacter baumannii. Antimicrob. Agents Chem. 56:3826-3832.
2. Roca I, Espinal P, Martí S, Vila J. 2011. First identification and characterization of an AdeABC-like efflux pump in Acinetobacter genomospecies 13TU. Antimicrob. Agents Chemother. 55:1285-1286.
3. Dupont M, Pages JM, Lafitte D, Siroy A, Bollet C. 2005. Identification of an OprD homologue in Acinetobacter baumannii. J. Proteome Res. 4:2386-2390.
4. Fernández-Cuenca F, Smani Y, Gomez-Sanchez MC, Docobo-Perez F, Caballero-Moyana FJ, Dominguez-Herrera J, Pascual A, Pachon J. 2011. Attenuated virulence of a slow-growing pandrug-resistant Acinetobacter baumannii is associated with decreased expression of genes encoding the porins CarO and OprD-like. Int. J. Antimicrob. Agents 38:548-549.
5. Luo L, Jiang X, Wu Q, Wei L, Li J, Ying C. 2011. Efflux pump overexpression in conjunction with alternation of outer membrane protein may induce Acinetobacter baumannii resistant to imipenem. Chemotherapy 57: 77-84.