Carbapenem-resistant Acinetobacter baumannii from Serbia: Revision of CarO classification

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Novovic, Katarina ^a   Mihajlovic, Sanja ^a   Vasiljevic, Zorica ^b   Filipic, Brankica ^a   Begovic, Jelena ^a   Jovcic, Branko ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b Institute for Mother and Child Health Care of Serbia Dr Vukan Čupić ^*  (Serbia)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; AZTREONAM; BACTERIAL ENZYME; BACTERIAL PROTEIN; BETA LACTAMASE AMPC; CARBAPENEM; CARO PROTEIN; CEFEPIME; CEFOTAXIME; CEFOXITIN; CEFTAZIDIME; CEPHALOSPORINASE; IMIPENEM; IMP METALLO BETA LACTAMASE; MEROPENEM; METALLO BETA LACTAMASE; NEW DELHI METALLO BETA LACTAMASE; OXACILLINASE OXA 143; OXACILLINASE OXA 23; OXACILLINASE OXA 235; OXACILLINASE OXA 24; OXACILLINASE OXA 51; OXACILLINASE OXA 58; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; UNCLASSIFIED DRUG; VIMENTIN; BETA LACTAMASE; CARBAPENEM DERIVATIVE; OUTER MEMBRANE PROTEIN; OXACILLINASE; PORIN;

ACINETOBACTER BAUMANNII; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; BOOTSTRAPPING; CARO GENE; COMPUTER MODEL; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME SYNTHESIS; GENE INSERTION SEQUENCE; GENE TRANSFER; GENETIC DIFFERENCE; GENETIC VARIABILITY; GENOTYPE; IC50; MINIMUM INHIBITORY CONCENTRATION; MULTIPLEX POLYMERASE CHAIN REACTION; NONHUMAN; PHYLOGENETIC TREE; PROTEIN LOCALIZATION; PULSED FIELD GEL ELECTROPHORESIS; SEQUENCE ALIGNMENT; SERBIA; STOP CODON; CHILD; CLASSIFICATION; DRUG EFFECTS; GENETIC POLYMORPHISM; GENETICS; GENOTYPING TECHNIQUE; HUMAN; ISOLATION AND PURIFICATION; MOLECULAR GENETICS;

ACINETOBACTER; ACINETOBACTER BAUMANNII;

ACINETOBACTER BAUMANNII; BACTERIAL OUTER MEMBRANE PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CARBAPENEMS; CHILD; GENOTYPING TECHNIQUES; HUMANS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; PORINS; SERBIA;

EID: 84926430178     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0122793     Document Type: Article

References (44)

1. Baang JH, Axelrod P, Decker BK, Hujer AM, Dash G, Truant AR et al. Longitudinal epidemiology of multidrug-resistant (MDR) Acinetobacter species in a tertiary care hospital. Am J Infect Control. 2012; 40: 134-137. doi: 10.1016/j.ajic.2011.04.326 PMID: 21835501
2. Chung DR, Song JH, Kim SH, Thamlikitkul V., Huang SG, Wang H et al. High prevalence of multi-drugresistant nonfermenters in hospital-acquired pneumonia in Asia. Am J Respir Crit Care Med. 2011; 184: 1409-1417. doi: 10.1164/rccm.201102-0349OC PMID: 21920919
3. Lockhart SR, Abramson MA, Beekmann SE, Gallagher G, Riedel S, Diekema DJ et al. Antimicrobial resistance among Gram-negative bacilli causing infections in intensive care unit patients in the United States between 1993 and 2004. J Clin Microbiol. 2007; 45: 3352-3359. PMID: 17715376
4. Kempf M, Rolain JM. Emergence of resistance to carbapenems in Acinetobacter baumannii in Europe: clinical impact and therapeutic options. Int J Antimicrob Agents. 2012; 39: 105-114. doi: 10.1016/j.ijantimicag.2011.10.004 PMID: 22113193
5. Zarrilli R, Giannouli M, Tomasone F, Triassi M, Tsakris A. Carbapenem resistance in Acinetobacter baumannii: the molecular epidemic features of an emerging problem in health care facilities. J Infect Dev Ctries. 2009; 3: 481-489.
6. Turton JF, Ward ME, Woodford N, Kaufmann ME, Pike R, Livermore DM et al. The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii. FEMS Microbiol Lett. 2006; 258: 72-77. PMID: 16630258
7. Poirel L, Nordmann P. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect. 2006; 12: 826-836. PMID: 16882287
8. Catel-Ferreira M, Coadou G, Molle V, Mugnier P, Nordmann P, Siroy A et al. Structure-function relationships of CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumannii. J Antimicrob Chemother. 2011; 66: 2053-2056. doi: 10.1093/jac/dkr267 PMID: 21705362
9. Mussi MA, Relling VM, Limansky AS, Viale AM. CarO, an Acinetobacter baumannii outer membrane protein involved in carbapenem resistance, is essential for L-ornithine uptake. FEBS Letters. 2007; 581: 5573-5578. PMID: 17997983
10. Siroy A, Molle V, Lemaitre-Guillier C, Vallenet D, Pestel-Caron M, Cozzone A, et al. Channel formation by CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumannii. Antimicrob. Agents Chemother. 2005; 49: 4876-4883. PMID: 16304148
11. Gottig S, Pfeifer Y, Wichelhaus TA, Zacharowski K, Bingold T, Averhoff B et al. Global spread of New Delhi metallo-beta-lactamase 1. Lancet Infect Dis. 2010; 10: 828-829. doi: 10.1016/S1473-3099(10)70274-7 PMID: 21109168
12. Poirel L, Bonnin RA, Boulanger A, Schrenzel J, Kaase M, Nordmann P. Tn125-related acquisition of blaNDM-like genes in Acinetobacter baumannii. Antimicrob Agents Chemother. 2012; 56: 1087-1089. doi: 10.1128/AAC.05620-11 PMID: 22143526
13. Schreckenberger PC, Daneshvar MI, Weyant RS, Hollis DG. Acinetobacter, Achromobacter, Chryseobacterium, Moraxella, and other nonfermentative Gram-negative rods, in: Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, RH Y. (Eds.), Manual of Clinical Microbiology. 8th ed. American Society for Microbiology, Washington, D.C., 2003; pp. 749-779.
14. Jovcic B, Begovic J, Lozo J, Topisirovic L, Kojic M. Dynamics of sodium dodecyl sulfate utilization andantibiotic susceptibility of strain Pseudomonas sp. ATCC19151. Arch Biol Sci. 2009; 61: 159-164.
15. Kojic M, Strahinic I, Topisirovic L. Proteinase PI and lactococcin A genes are located on the largest plasmid in Lactococcus lactis subsp. lactis bv. diacetylactis S50. Can J Microbiol. 2005; 51: 305-314. PMID: 15980892
16. Turton FJ, Gabriel SN, Valderrey C, Kaufmann ME, Pitt TL. Use of sequence-based typing and multiplex PCR to identify clonal lineages of outbrake strains of Acinetobacter baumannii. Clin Microbiol Infect. 2007; 13: 807-815. PMID: 17610600
17. Beceiro A, Perez A, Fernandez-Cuenca F, Martinez-Martinez L, Pascual A, Vila J et al.Genetic variability among ampC genes from Acinetobacter genomic species 3. Antimicrob Agents Chemother. 2009; 53: 1177-1184. doi: 10.1128/AAC.00485-08 PMID: 19029333
18. Mussi MA, Limansky AS, Relling V, Ravasi P, Arakaki A, Actis LA et al. Horizontal gene transfer and assortative recombination within the Acinetobacter baumannii clinical population provide genetic diversity at the single carO gene, encoding a major outer membrane protein channel. J Bact. 2011; 193: 4736-4748. doi: 10.1128/JB.01533-10 PMID: 21764928
19. Teo J, Ngan G, Balm M, Jureen R, Krishnan P, Lin R. Molecular characterization of NDM-1 producing Enterobacteriaceae isolates in Singapore hospitals. Western Pac Surveill Response. 2012; J 3: 19-24. doi: 10.5365/WPSAR.2011.2.4.010 PMID: 23908903
20. Woodford N, Fagan EJ, Ellington MJ. Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum (beta)-lactamases. J Antimicrob Chemother. 2006; 57: 154-155. PMID: 16284100
21. Higgins P, Perez-Llarena PJ, Zander E, Fernandez A, Bou G, Sifert H. OXA-235 a novel class D β-lactamase involved in resistance to carbapenems in Acinetobacter baumannii. Antimicrob Agents Chemother. 2013; 57(5): 2121-2126. doi: 10.1128/AAC.02413-12 PMID: 23439638
22. Higgins P, Lehmann M, Seifert H. Inclusion of OXA-143 primers in multiplex polymerase chain reaction (PCR) for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. Int J Antimicrob Agents. 2010; 35(3): 305. doi: 10.1016/j.ijantimicag.2009.10.018 PMID: 20031376
23. Ellington M J, Kistler J, Livermore DM, Woodford M. Multiplex PCR for rapid detection of genes encoding acquired metallo-β-lactamases. J Antimicrob Chemother. 2007; 59:321-322. PMID: 17185300
24. Wolter DJ, Khalaf N, Robledo IE, Vazguez GJ, Sante MI, Aquino EE et al. Surveillance of carbapenem-resistant Pseudomonas aeruginosa isolates from Puerto Rico medical center hospitals: dissemination of KPC and IMP-18 β-lactamases. 2009; Antimicrob Agents Chemother 53(4): 1660-1664. doi: 10.1128/AAC.01172-08 PMID: 19188398
25. Marck C. 'DNA Strider': a 'C' program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers. Nucleic Acids Res. 1988; 16: 1829-1836. PMID: 2832831
26. Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994; 22: 4673-4680. PMID: 7984417
27. Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, MillerWet al. Gapped BLAST and PSIBLAST: a new generation of protein database search programs. Nucleic Acids Res. 1997; 25: 3389-3402. PMID: 9254694
28. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S. MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol. 2013; 30: 2725-2729. doi: 10.1093/molbev/mst197 PMID: 24132122
29. Bagos PG, Liakopoulos TD, Spyropoulos IC, Hamodrakas SJ. A Hidden Markov Model method, capable of predicting and discriminating beta-barrel outer membrane proteins. BMC Bioinformatics. 2004; 5: 29. PMID: 15070403
30. Shannon CE. A mathematical theory of communication. Bell Syst Tech J. 1948; 27: 379-423, 623-656.
31. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995; 33: 2233-2239. PMID: 7494007
32. Turton JF, Shah J, Ozongwu C, Pike R. Incidence of Acinetobacter species other than A. baumannii among clinical isolates of Acinetobacter: evidence for emerging species. J Clin Microbiol. 2010; 48: 1445-1449. doi: 10.1128/JCM.02467-09 PMID: 20181894
33. Mussi MA, Limansky AS, Viale AM. Acquisition of resistance to carbapenems in multidrug-resistant clinical strains of Acinetobacter baumannii: natural insertional inactivation of a gene encoding a member of a novel family of beta-barrel outer membrane proteins. Antimicrob Agents Chemother. 2005; 49: 1432-1440. PMID: 15793123
34. Zarrilli R, Casillo R, Di Popolo A, Tripodi MF, Bagattini M, Cuccurullo S et al. Molecular epidemiology of a clonal outbreak of multidrug-resistant Acinetobacter baumannii in a university hospital in Italy. Clin Microbiol Infect. 2007; 13: 481-489. PMID: 17430339
35. Mezzatesta ML, D'Andrea MM, Migliavacca R, Giani T, Gona F, Nucleo E et al. Epidemiological characterization and distribution of carbapenem-resistant Acinetobacter baumannii clinical isolates in Italy. Clin Microbiol Infect. 2012; 18: 160-166. doi: 10.1111/j.1469-0691.2011.03527.x PMID: 21722261
36. Pfeifer Y, Wilharm G, Zander E, Wichelhaus TA, Göttig S, Hunfeld KP et al. Molecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007. J Antimicrob Chemother. 2011; 66: 1998-2001. doi: 10.1093/jac/dkr256 PMID: 21693460
37. Bou G, Oliver A, Martinez-Beltran J. OXA-24, a novel class D β-lactamase with carbapenemase activity in Acinetobacter baumannii clinical strain. Antimicrob Agents Chemother. 2000; 44(6): 1556-1561. PMID: 10817708
38. Perez F, Hujer AM, Hujer KM, Decker BK, Rather PN, Bonomo RA. Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother. 2007; 51: 3471-3484. PMID: 17646423
39. Roca I, Espinal P, Vila-Farres X, Vila J. The Acinetobacter baumannii oxymoron: commensal hospital dweller turned pan-drug-resistant menace. Front Microbiol. 2012; 3: 148. doi: 10.3389/fmicb.2012.00148 PMID: 22536199
40. Jovcic B, Lepsanovic Z, Suljagic V, Rackov G, Begovic J, Topisirovic L et al. Emergence of NDM-1 metallo-beta-lactamase in Pseudomonas aeruginosa clinical isolates from Serbia. Antimicrob Agents Chemother. 2011; 55: 3929-3931. doi: 10.1128/AAC.00226-11 PMID: 21646490
41. Mirovic V, Tomanovic B, Lepsanovic Z, Jovcic B, Kojic M. Isolation of Klebsiella pneumoniae producing NDM-1 metallo-beta-lactamase from the urine of an outpatient baby boy receiving antibiotic prophylaxis. Antimicrob Agents Chemother. 2012; 56: 6062-6063. doi: 10.1128/AAC.00838-12 PMID: 22908159
42. Lee Y, Kim CK, Lee H, Jeong SH, Yong D, Lee K. A novel insertion sequence, ISAba10, inserted into ISAba1 adjacent to the bla(OXA-23) gene and disrupting the outer membrane protein gene carO in Acinetobacter baumannii. Antimicrob Agents Chemother. 2011; 55: 361-363. doi: 10.1128/AAC.01672-09 PMID: 20937784
43. Lu P-L, Doumith M, Livermore DM, Chen T-P, Woodford N. Diversity of carbapenem resistance mechanisms in Acinetobacter baumannii from a Taiwan hospital: spread of plasmid-borne OXA-72 carbapenemase. J Antimicrob Chemother. 2009; 63: 641-647. doi: 10.1093/jac/dkn553 PMID: 19182237
44. Fonseca EL, Scheidegger E, Freitas FS, Cipriano R, Vicente AC. Carbapenem-resistant Acinetobacter baumannii from Brazil: role of carO alleles expression and blaOXA-23 gene. BMC Microbiol. 2013; 13: 245. doi: 10.1186/1471-2180-13-245 PMID: 24195496