Adult onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) and Nasu–Hakola disease: lesion staging and dynamic changes of axons and microglial subsets

Brain Pathology

Volumn 27, Issue 6, 2017, Pages 748-769

  Oyanagi, Kiyomitsu ^a,b   Kinoshita, Michiaki ^c   Suzuki Kouyama, Emi ^a   Inoue, Teruhiko ^d   Nakahara, Asa ^a,e   Tokiwai, Mika ^a,s   Arai, Nobutaka ^f   Satoh, Jun Ichi ^g   Aoki, Naoya ^f,h   Jinnai, Kenji ⁱ   Yazawa, Ikuru ^j   Arai, Kimihito ^k   Ishihara, Kenji ^l,m   Kawamura, Mitsuru ^l   Ishizawa, Keisuke ⁿ   Hasegawa, Kazuko ^o   Yagisita, Saburo ^p   Amano, Naoji ^a,t   Yoshida, Kunihiro ^a   Terada, Seishi ^q   Yoshida, Mari ^r   Akiyama, Haruhiko ^f   Mitsuyama, Yoshio ^d   Ikeda, Shu Ichi ^a   more..

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Hatsuishi Hospital   (Japan)

^c Suwa Red Cross Hospital   (Japan)

^d Daigo Hospital   (Japan)

^e NIIGATA UNIVERSITY   (Japan)

^f TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^g MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^h YOKOHAMA CITY UNIVERSITY MEDICAL CENTER   (Japan)

ⁱ Japan   (Japan)

^j NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^k SAKURA NATIONAL HOSPITAL   (Japan)

^l SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^m Ushioda General Hospital   (Japan)

ⁿ SAITAMA MEDICAL UNIVERSITY   (Japan)

^o SAGAMIHARA NATIONAL HOSPITAL   (Japan)

^p KANAGAWA REHABILITATION CENTER   (Japan)

^q OKAYAMA UNIVERSITY   (Japan)

^r AICHI MEDICAL UNIVERSITY   (Japan)

^s SHINSHU UNIVERSITY HOSPITAL   (Japan)

^t Present address of Naoji Amano: Okaya Municipal Hospital   (Japan)

more..

Author keywords

ALSP; Hakola; HDLS; lesion staging; microglia; Nasu

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN; CALCIUM BINDING PROTEIN; CD163 ANTIGEN; CD20 ANTIGEN; CD204 ANTIGEN; CD3 ANTIGEN; CD68 ANTIGEN; COLONY STIMULATING FACTOR 1; COLONY STIMULATING FACTOR RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; IBA1 PROTEIN; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; LYMPHOCYTE ANTIGEN; MYELIN BASIC PROTEIN; SCAVENGER RECEPTOR; SYNAPTOPHYSIN; SYNUCLEIN; TAR DNA BINDING PROTEIN; TAU PROTEIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; UNCLASSIFIED DRUG;

ADULT; ADULT DISEASE; ADULT ONSET LEUKOENCEPHALOPATHY WITH AXONAL SPHEROIDS AND PIGMENTED GLIA; ARTICLE; AUTOPSY; AXON; BRAIN ATROPHY; BRAIN STEM; BRAIN THIRD VENTRICLE; BRAIN VENTRICLE DILATATION; CAPSULA INTERNA; CELL DENSITY; CELL SHAPE; CELL SUBPOPULATION; CEREBELLUM; CLINICAL FEATURE; CONTROLLED STUDY; EPILEPSY; FEMALE; FRONTAL CORTEX; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LATERAL BRAIN VENTRICLE; LEUKODYSTROPHY; LEUKOENCEPHALOPATHY; LYMPHOCYTIC INFILTRATION; MALE; MICROGLIA; MIDDLE AGED; NASU HAKOLA DISEASE; NERVE DEGENERATION; NEUROLOGIC EXAMINATION; NEUROPATHOLOGY; PIGMENTARY ORTHOCHROMATIC LEUKODYSTROPHY; PONS; STAGING; WHITE MATTER; WHITE MATTER LESION; ATROPHY; BRAIN; CHONDRODYSPLASIA; GLIA; JAPAN; LIPODYSTROPHY; PATHOLOGY; SUBACUTE SCLEROSING PANENCEPHALITIS;

ADULT; ATROPHY; AUTOPSY; AXONS; BRAIN; FEMALE; HUMANS; JAPAN; LEUKOENCEPHALOPATHIES; LIPODYSTROPHY; MALE; MICROGLIA; MIDDLE AGED; NEUROGLIA; OSTEOCHONDRODYSPLASIAS; SUBACUTE SCLEROSING PANENCEPHALITIS; WHITE MATTER;

EID: 85014249759     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/bpa.12443     Document Type: Article

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