Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts

Blood

Volumn 128, Issue 17, 2016, Pages 2153-2164

  Kohli, Shrey ^a   Ranjan, Satish ^a   Hoffmann, Juliane ^a   Kashif, Muhammed ^b   Daniel, Evelyn A ^a   Al Dabet, Moh'D Mohanad ^a   Bock, Fabian ^a   Nazir, Sumra ^a   Huebner, Hanna ^c   Mertens, Peter R ^d   Fischer, Klaus Dieter ^e   Zenclussen, Ana C ^f   Offermanns, Stefan ^g   Aharon, Anat ^h   Brenner, Benjamin ^h   Shahzad, Khurrum ^a,i   Ruebner, Matthias ^c   Isermann, Berend ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^d Diabetes and Endocrinology   (Germany)

^e Institute of Biochemistry and Cell Biology   (Germany)

^f UNIVERSITY HOSPITAL MAGDEBURG   (Germany)

^g MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^h RAMBAM MEDICAL CENTER   (Israel)

ⁱ UNIVERSITY OF HEALTH SCIENCES   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CRYOPYRIN; FMS LIKE TYROSINE KINASE 1; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PADGEM PROTEIN; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR NF E2 P45 SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; ELEVATED BLOOD PRESSURE; EXOSOME; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATION; INTRAUTERINE GROWTH RETARDATION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PLACENTA; PLACENTA DISORDER; PREECLAMPSIA; PREGNANCY DISORDER; PRIORITY JOURNAL; PROTEINURIA; THROMBOCYTE ACTIVATION; TROPHOBLAST; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; THROMBOCYTE; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; BLOOD PLATELETS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR VESICLES; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INFLAMMASOMES; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; PLATELET ACTIVATION; PRE-ECLAMPSIA; PREGNANCY; TROPHOBLASTS;

EID: 85014152809     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2016-03-705434     Document Type: Article

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