Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles

Journal of Clinical Investigation

Volumn 125, Issue 4, 2015, Pages 1471-1484

  Rothmeier, Andrea S ^a   Marchese, Patrizia ^a   Petrich, Brian G ^b   Furlan Freguia, Christian ^a   Ginsberg, Mark H ^c   Ruggeri, Zaverio M ^a   Ruf, Wolfram ^a,d  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATE; CELL SURFACE RECEPTOR; CYSTEINE PROTEINASE; FILAMIN; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; LACTADHERIN; PROCOAGULANT; PURINERGIC P2X7 RECEPTOR; THIOREDOXIN; THIOREDOXIN REDUCTASE;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; EXTRACELLULAR SPACE; FIBRIN DEPOSITION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIPID RAFT; MEMBRANE MICROPARTICLE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OXIDATION REDUCTION POTENTIAL; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TISSUE INJURY; ANIMAL; C57BL MOUSE; CELL MEMBRANE; EXTRACELLULAR FLUID; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; PATHOPHYSIOLOGY; PHYSIOLOGY; PSEUDOPODIUM; SIGNAL TRANSDUCTION; THROMBOSIS;

ACTINS; ADENOSINE TRIPHOSPHATE; ANIMALS; CASPASE 1; CELL-DERIVED MICROPARTICLES; EXTRACELLULAR FLUID; IMMUNITY, INNATE; INFLAMMASOMES; INFLAMMATION; MACROPHAGES; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED C57BL; PSEUDOPODIA; RECEPTORS, PURINERGIC P2X7; SIGNAL TRANSDUCTION; THIOREDOXIN-DISULFIDE REDUCTASE; THIOREDOXINS; THROMBOSIS;

EID: 84926333598     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI79329     Document Type: Article

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