Autonomous Generation and Loading of DNA Guides by Bacterial Argonaute

Molecular Cell

Volumn 65, Issue 6, 2017, Pages 985-998.e6

  Swarts, Daan C ^a   Szczepaniak, Malwina ^b   Sheng, Gang ^c   Chandradoss, Stanley D ^b   Zhu, Yifan ^a   Timmers, Elizabeth M ^a   Zhang, Yong ^c   Zhao, Hongtu ^c   Lou, Jizhong ^c   Wang, Yanli ^c,d   Joo, Chirlmin ^b   van der Oost, John ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c INSTITUTE OF BIOPHYSICS   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

ago; DNA chopping; guide generation; guide loading; pAgo; prokaryotic argonaute; RNA interference; siDNA; small interfering DNA; TtAgo

Indexed keywords

ARGONAUTE PROTEIN; DEOXYCYTIDINE; DEOXYGUANOSINE; DNA; DOUBLE STRANDED DNA; BACTERIAL DNA; BACTERIAL PROTEIN; COMPLEMENTARY DNA; PROTEIN BINDING;

ARTICLE; FLUORESCENCE; NONHUMAN; THERMUS THERMOPHILUS; BINDING SITE; CHEMISTRY; CONFORMATION; ENZYMOLOGY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETICS; METABOLISM; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; SINGLE MOLECULE IMAGING; STRUCTURE ACTIVITY RELATION;

ARGONAUTE PROTEINS; BACTERIAL PROTEINS; BINDING SITES; DEOXYCYTIDINE; DEOXYGUANOSINE; DNA, ANTISENSE; DNA, BACTERIAL; FLUORESCENCE RESONANCE ENERGY TRANSFER; MOLECULAR DYNAMICS SIMULATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; SINGLE MOLECULE IMAGING; STRUCTURE-ACTIVITY RELATIONSHIP; THERMUS THERMOPHILUS;

EID: 85014129509     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2017.01.033     Document Type: Article

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